219 publication(s) trouvée(s)
Article scientifique
Comparative effectiveness of lipid-nutrient spread supplementation regimens for moderate acute malnutrition in Ethiopia: The MODAM-MAM individually randomized controlled trial
BACKGROUND: Moderate acute malnutrition (MAM), affecting over 30 million children globally, substantially increases the risk of morbidity and mortality. In …
Article scientifique
Adherence to medications, lifestyle advice, and self-monitoring for type 2 diabetes and hypertension in sub-Saharan Africa: A systematic review, meta-analysis, and interactive network analysis
BACKGROUND: Type 2 diabetes and hypertension are major public health challenges in sub-Saharan Africa, yet treatment control remains poor. Patient …
Article scientifique
Estimates of global burden of snakebite: A literature review and geostatistical modelling study
BACKGROUND: Snake envenoming (SE) remains an important public health problem, disproportionately affecting impoverished rural communities in tropical and subtropical regions. …
Article scientifique
Hypertension and diabetes prevalence, associated factors, care cascade, and quality of life in older adults: A cross-sectional population-based study in The Gambia, South Africa, and Zimbabwe
BACKGROUND: Hypertension and diabetes prevalence are increasing across Africa. We investigated the prevalence, associated factors, achievement of stages within the …
Article scientifique
Multilevel onsite training and mentorship model to accelerate early childhood cancer diagnosis in Northwest Ethiopia: A quasi-experimental mixed method study
BACKGROUND: Childhood cancer survival in low-income countries remains below 20%, with late recognition and delayed referral commonly reported. In Northwest …
Article scientifique
Prediction of hospitalisation in young children with pneumonia in Malawi: A machine learning-based approach
BACKGROUND: Globally, pneumonia remains the single biggest cause of mortality in children under 5 years of age. This study sought …
Article scientifique
Pathways of emergency care for severely ill children in Nigerian and Ugandan hospitals: A process mapping study
BACKGROUND: Child mortality remains high in countries with weak emergency care systems. Facility organisation for paediatric emergency care is heterogeneous …
Article scientifique
Health system use and experience among people with poor mental health: A cross-sectional analysis of the People’s Voice Survey in 18 countries
BACKGROUND: Across the globe, rates of depression and anxiety have risen substantially since the COVID pandemic. Consequently, poor mental health …
Article scientifique
Point-of-care early infant HIV diagnosis at birth in a pragmatic cluster-randomized trial in Mozambique and Tanzania: A comparative cost and cost-effectiveness study
BACKGROUND: Timely access to early infant diagnosis (EID) is crucial for newborns with HIV, as late diagnosis can delay lifesaving …
Article scientifique
HIV self-testing and the global diagnostic gap: Addressing a decade of missed opportunity
In 2015, a survey-based analysis across 16 sub-Saharan African countries estimated that nearly half of people living with HIV were …
Article scientifique
The longitudinal care cascade for hypertension in people with and without HIV in South Africa: A clinic-based observational study
BACKGROUND: Hypertension (HTN) constitutes a major and growing public health challenge in South Africa, a setting where HIV prevalence also …
Article scientifique
HIV diagnosis and treatment status in individuals dying from HIV in Zimbabwe, Malawi, and South Africa: A model comparison analysis
BACKGROUND: Antiretroviral therapy (ART) has greatly reduced HIV-related mortality and improved life expectancy in sub-Saharan Africa since the early 2000s. …
Article scientifique
Multimodal protective and susceptibility clusters in paediatric atopic dermatitis: A machine learning-based, data-driven observational study
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease that typically develops in early childhood. Differences in AD prevalence …
Article scientifique
Effect of a person-centered care intervention on return and sustained reengagement after treatment interruptions from HIV care in Zambia: A post-hoc analysis of a stepped-wedged cluster randomized trial
BACKGROUND: Poor client-provider interactions lead to reinforcing cycles of treatment interruptions (TIs) from HIV care and fear of return, undermining …
Article scientifique
Changes in child mortality and population health following 10 years of health systems strengthening in rural Madagascar: A longitudinal cohort study
BACKGROUND: Reducing child mortality rates is a unifying goal of the global health and international development communities. In Africa, unambiguous …
Article scientifique
Effectiveness of a brief intervention and text-based booster in the emergency department to reduce harmful and hazardous alcohol use: A pragmatic randomized adaptive clinical trial in Moshi, Tanzania
BACKGROUND: Alcohol use contributes to over 3 million deaths annually. In Tanzania, there are no evidence-based culturally adapted interventions to …
Article scientifique
Vaccination strategies to achieve outbreak control for MPXV Clade I with a one-time mass campaign in sub-Saharan Africa: A scenario-based modelling study
BACKGROUND: Limited mpox vaccination coverage, declining cross-protection from historical smallpox vaccination campaigns, and persistent zoonotic reservoirs leave many sub-Saharan countries …
Article scientifique
Re-evaluating malarial retinopathy to improve its diagnostic accuracy in paediatric cerebral malaria: A retrospective study
BACKGROUND: Previous work has identified that malarial retinopathy has diagnostic value in paediatric cerebral malaria (CM). To improve our understanding …
Article scientifique
Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia
BACKGROUND: Timely response to treatment failure is critical for improved outcomes and viral re-suppression among people living with HIV, but …
Article scientifique
Adherence thresholds for emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis against HIV acquisition in cisgender women: A randomized directly observed dosing study
BACKGROUND: Oral emtricitabine/tenofovir disoproxil fumarate (F/TDF) preexposure prophylaxis (PrEP) effectiveness against HIV acquisition highly depends on adherence. For men who …
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