1320 publication(s) trouvée(s)
Article scientifique
Preclinical animal models for onchocerciasis and loiasis: A systematic review of applications in drug screening
BACKGROUND: Onchocerciasis and loiasis are co-endemic filarial neglected tropical diseases in Central and West Africa. While ivermectin-based mass drug administration …
Article scientifique
Epidemiological insights and genetic diversity of the Duffy binding protein of Plasmodium vivax in Duffy-negative Cameroonians
BACKGROUND: Malaria remains a major public health concern in sub-Saharan Africa. Plasmodium vivax (P. vivax), historically considered rare due to …
Article scientifique
Prevalence of multiple human intestinal parasites across diverse environments in Madagascar
BACKGROUND: Intestinal parasitic infections affect more than 1·5 billion people globally, leading to severe health consequences such as malnutrition, anemia, …
Article scientifique
Geographical disparities and programmatic determinants of hydrocele surgery and lymphoedema management coverage for lymphatic filariasis in the Democratic Republic of the Congo, 2018–2024: A national analysis of routine programme data
BACKGROUND: Lymphatic filariasis (LF) is a significant neglected tropical disease in the Democratic Republic of the Congo (DRC). Although progress …
Article scientifique
Factors affecting detection and quantification of Schistosoma haematobium eggs in pooled urine samples
BACKGROUND: Building on our previous work showing that pooled urine testing can rapidly detect Schistosoma haematobium infections but has limited …
Article scientifique
Plant-based therapeutics for leishmaniasis: A systematic review emphasizing human studies and clinical trial evidence
BACKGROUND: Leishmaniasis is a parasitic disease caused by Leishmania species and transmitted through sand fly bites, affecting some of the …
Article scientifique
Performance of fecal inflammatory biomarkers to identify watery shigellosis: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study
BACKGROUND: Current syndromic guidelines for diarrhea treatment miss watery Shigella cases, leading to undertreatment of children who may benefit. Incorporating …
Article scientifique
Diagnostic competence and health worker knowledge of female genital schistosomiasis management in a rural Ghanaian district
Abstract Background Schistosomiasis is a neglected tropical disease with a greater burden in Africa, including Ghana. Female Genital Schistosomiasis (FGS), …
Article scientifique
High-resolution automated mapping of potential Aedes larval container habitats using drone imagery and supervised machine learning in Dar es Salaam, Tanzania
Larval source management is a key strategy to control the spread of Aedes-borne viral diseases including dengue, Zika, chikungunya, and …
Article scientifique
Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis
BACKGROUND: Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral …
Article scientifique
Systematic review of health risk assessment in Africa’s bushmeat trade: Are there any risks assessed?
BACKGROUND: The bushmeat trade in tropical Africa represents a major route for zoonotic disease emergence. Yet, the extent to which …
Article scientifique
Characterization of the first complete genome sequence of yellow fever virus (YFV) in Sierra Leone: Implications for public health
Yellow fever virus (YFV), a mosquito-borne orthoflavivirus that causes severe hemorrhagic disease, is endemic in parts of South America and …
Article scientifique
Three Leishmania species identified in domestic dogs in Tunisia: New insights into canine leishmaniosis
BACKGROUND: Tunisia represents the perfect example of a Mediterranean Country where different Leishmania species may express their infectivity causing Visceral …
Article scientifique
Mass drug administration for soil-transmitted helminthiasis and schistosomiasis in selected districts of Rwanda: Coverage, implementation factors, and household water, sanitation, and hygiene conditions
BACKGROUND: In Rwanda, about 1 in 3 people are affected by soil-transmitted helminthiases (38.7%) and 1 in 4 by schistosomiasis …
Article scientifique
Mycetoma as a major cause of limb amputation in Northeastern Ethiopia: A facility-based retrospective study
Background Mycetoma is a chronic, progressively destructive infection that can result in severe disability and limb loss. In Ethiopia, diagnostic …
Article scientifique
Field deployment of a mobile suitcase laboratory for Buruli ulcer diagnosis in Ghana
Molecular diagnostics are the gold standard laboratory confirmation test for Buruli ulcer (BU), a severe necrotising skin disease caused by …
Article scientifique
Cholera in Africa: Current trends, challenges, and control towards elimination strategies
Cholera remains a substantial public health challenge in Africa, despite the availability of effective vaccines, treatment, and preventive measures. Systemic …
Article scientifique
Local heterogeneity in Lassa fever serology in rural Nigeria: Implications for vaccine trial site selection
INTRODUCTION: Lassa virus (LASV) causes significant morbidity in West Africa, yet vaccine trial planning is hampered by a lack of …
Article scientifique
Outbreak of dengue fever in Ghana: The emergence of DENV-1 serotype
BACKGROUND: Dengue, a mosquito-borne virus continues to be a public health concern in the tropics and subtropical parts of Africa. …
Article scientifique
Accuracy of AI-assisted diagnostic tools for Schistosoma haematobium: A systematic review and meta-analysis
BACKGROUND: Urogenital schistosomiasis caused by Schistosoma haematobium remains endemic in sub-Saharan Africa. Diagnosis traditionally relies on urine microscopy to detect …