9011 publication(s) trouvée(s)
Article scientifique
Steatosis in South African women: How much and why?
BACKGROUND: Globally, steatosis is the commonest type of liver pathology and is closely associated with obesity and the metabolic syndrome. …
Article scientifique
Difficult decisions: Evaluating individual and couple-level fertility intentions and HIV acquisition among HIV serodiscordant couples in Zambia
INTRODUCTION: Attempts to conceive and pregnancy may increase HIV transmission to sex partners and infants. Our study evaluated the association …
Article scientifique
Association of maternal KIR gene content polymorphisms with reduction in perinatal transmission of HIV-1
The role of killer cell immunoglobulin-like receptors (KIRs) in the transmission of HIV-1 has not been extensively studied. Here, we …
Article scientifique
Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner
Dendritic cell (DC)-to-T cell transmission is an example of infection in trans, in which the cell transmitting the virus is …
Article scientifique
Using community-based reporting of vital events to monitor child mortality: Lessons from rural Ghana
BACKGROUND: Reducing neonatal and child mortality is a key component of the health-related sustainable development goal (SDG), but most low …
Article scientifique
Developmental and reproductive performance of a specialist herbivore depend on seasonality of, and light conditions experienced by, the host plant
Host plant phenology (as influenced by seasonality) and light-mediated changes in the phenotypic and phytochemical properties of leaves have been …
Article scientifique
Burden of invasive pneumococcal disease among children in rural Mozambique: 2001-2012
BACKGROUND: Invasive pneumococcal disease (IPD) is a major cause of illness and death among children worldwide. 10-valent pneumococcal conjugate vaccine …
Article scientifique
First report of occult hepatitis B infection among ART naïve HIV seropositive individuals in Maputo, Mozambique
BACKGROUND: The prevalence of hepatitis B virus (HBV) infection and human immunodeficiency virus (HIV) infection in Mozambique is one of …
Article scientifique
Empiric tuberculosis treatment in South African primary health care facilities - for whom, where, when and why: Implications for the development of tuberculosis diagnostic tests
BACKGROUND: The extent and circumstances under which empiric tuberculosis (TB) treatment (treatment without microbiological confirmation at treatment initiation) is administered …
Article scientifique
Incremental cost-effectiveness of screening and laser treatment for diabetic retinopathy and macular edema in Malawi
OBJECTIVE: To investigate the economic impact of introducing targeted screening and laser photocoagulation treatment for sight-threatening diabetic retinopathy and macular …
Article scientifique
A parsimonious characterization of change in global age-specific and total fertility rates
This study aims to understand trends in global fertility from 1950-2010 though the analysis of age-specific fertility rates. This approach …
Article scientifique
Evaluation of a point-of-care immunoassay test kit ‘StrongStep’ for cryptococcal antigen detection
BACKGROUND: HIV-associated cryptococcal meningitis is the leading cause of adult meningitis in Sub-Saharan Africa, accounting for 15%-20% of AIDS-attributable mortality. …
Article scientifique
Inhaled nitric oxide and cognition in pediatric severe malaria: A randomized double-blind placebo controlled trial
BACKGROUND: Severe malaria is a leading cause of acquired neurodisability in Africa and is associated with reduced nitric oxide (NO) …
Article scientifique
Prevalence of relative systemic hypertension in adults with sickle cell disease in Ghana
Individuals with sickle cell disease particularly with the homozygous (SS) genotype historically have relatively low blood pressure. Nonetheless, they develop …
Article scientifique
Impact of mode of delivery on pregnancy outcomes in women with premature rupture of membranes after 28 weeks of gestation in a low-resource setting: A prospective cohort study
BACKGROUND: Despite the high prevalence of premature rupture of membranes (PROM) in low-resource settings, the preferred mode of delivery remains …
Article scientifique
Improving mapping for Ebola response through mobilising a local community with self-owned smartphones: Tonkolili District, Sierra Leone, January 2015
BACKGROUND: During the 2014-16 Ebola virus disease (EVD) outbreak, the Magburaka Ebola Management Centre (EMC) operated by Médecins Sans Frontières …
Article scientifique
Knowledge, attitudes and beliefs about the health hazards of biomass smoke exposure amongst commercial food vendors in Nigeria
BACKGROUND: Exposure to biomass smoke is a major cause of morbidity and mortality in Africa. Commercial food vendors in Nigeria …
Article scientifique
Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence
In Gabon, a central African country, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) are endemic. In a recent …
Article scientifique
“Every day they keep adding new tools but they don’t take any away”: Producing indicators for intermittent preventive treatment for malaria in pregnancy (IPTp) from routine data in Kenya
BACKGROUND: Intermittent preventive treatment for malaria in pregnancy (IPTp) is part of a multi-pronged strategy aimed at preventing malaria in …
Article scientifique
Sero-prevalence and risk factors for hepatitis E virus infection among pregnant women in the Cape Coast Metropolis, Ghana
BACKGROUND: Hepatitis E virus is an emerging infection in Africa with poor maternal and foetal outcomes. There is scanty data …