22 publication(s) trouvée(s)
Article scientifique
Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression
Rationale: Despite growing evidence for mitochondria's involvement in cancer, the roles of specific metabolic components outside the respiratory complex have …
Article scientifique
Targeting Epstein-Barr virus oncoprotein LMP1-mediated high oxidative stress suppresses EBV lytic reactivation and sensitizes tumors to radiation therapy: Erratum
[This corrects the article DOI: 10.7150/thno.46006.].
Article scientifique
Paradigm shift in future biophotonics for imaging and therapy: Miniature living lasers to cellular scale optoelectronics
Advancements in light technology, devices and its applications have tremendously changed the facets of biomedical science and engineering to provide …
Article scientifique
Plasma lipids signify the progression of precancerous gastric lesions to gastric cancer: a prospective targeted lipidomics study
Rationale: Gastric cancer (GC) is preceded by a stepwise progression of precancerous gastric lesions. Distinguishing individuals with precancerous gastric lesions …
Article scientifique
P2X2 receptors in pyramidal neurons are critical for regulating vulnerability to chronic stress
Rationale: Stress is a major risk factor for the development of depression. However, the underlying molecular mechanisms of stress vulnerability …
Article scientifique
Emerging nanozyme-based multimodal synergistic therapies in combating bacterial infections
Pathogenic infections have emerged as major threats to global public health. Multidrug resistance induced by the abuse of antibiotics makes …
Article scientifique
A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma (GB) remains a challenge. The current survival rate of …
Article scientifique
Versatile and Finely Tuned Albumin Nanoplatform based on Click Chemistry
Albumin is one of the most attractive nanoplatforms for targeted imaging and drug delivery due to its biocompatibility and long …
Article scientifique
Cardiac-mimetic cell-culture system for direct cardiac reprogramming
Rationale: Cardiovascular diseases often cause substantial heart damage and even heart failure due to the limited regenerative capacity of adult …
Article scientifique
Dual-Channel Fluorescence Imaging of Hydrogel Degradation and Tissue Regeneration in the Brain
The ability of brain tissue to regenerate is limited; therefore, brain diseases (i.e., trauma, stroke, tumors) often lead to irreversible …
Article scientifique
Au Hollow Nanorods-Chimeric Peptide Nanocarrier for NIR-II Photothermal Therapy and Real-time Apoptosis Imaging for Tumor Theranostics
The strategy that combines photodynamic therapy (PDT) and photothermal therapy (PTT) is widely used to achieve strong antitumor efficiency.Since light …
Article scientifique
New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments
: Our study highlights the relevance of new CXCR1/2 inhibitors for the treatment of RCC or HNSCC as first-line treatment …
Article scientifique
Distinct PD-L1/PD1 Profiles and Clinical Implications in Intrahepatic Cholangiocarcinoma Patients with Different Risk Factors
Rationale: PD1/PD-L1 immune checkpoint inhibitors have shown promising results for several malignancies. However, PD1/PD-L1 signaling and its therapeutic significance remains …
Article scientifique
Secreted protein acidic and rich in cysteine mediates active targeting of human serum albumin in U87MG xenograft mouse models
Human serum albumin (HSA) is the most abundant plasma protein. The main reason for using HSA as a versatile tool …
Article scientifique
Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer
Purpose: Colitis-associated colorectal cancer (CAC) poses substantial challenges for effective treatment. Currently, there is a considerable need for the development …
Article scientifique
GRP78-targeted ferritin nanocaged ultra-high dose of doxorubicin for hepatocellular carcinoma therapy
Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer deaths, primarily due to its high incidence of recurrence …
Article scientifique
CD28null pro-atherogenic CD4 T-cells explain the link between CMV infection and an increased risk of cardiovascular death
An increased risk of cardiovascular death in Cytomegalovirus (CMV)-infected individuals remains unexplained, although it might partly result from the fact …
Article scientifique
Integrative analysis of imaging and transcriptomic data of the immune landscape associated with tumor metabolism in lung adenocarcinoma: Clinical and prognostic implications
Although metabolic modulation in the tumor microenvironment (TME) is one of the key mechanisms of cancer immune escape, there is …
Article scientifique
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance
High rates of lethal outcome in tumour metastasis are associated with the acquisition of invasiveness and chemoresistance. Several clinical studies …
Article scientifique
Noninvasive Imaging of Myocardial Inflammation in Myocarditis using 68Ga-tagged Mannosylated Human Serum Albumin Positron Emission Tomography
The diagnosis of myocarditis traditionally relies on invasive endomyocardial biopsy but none of the imaging studies so far are specific …
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