17 publication(s) trouvée(s)
Article scientifique
Insight into antiphospholipid syndrome: the role and clinical utility of neutrophils extracellular traps formation
Antiphospholipid syndrome (APLS) is a systemic immune dysregulation distinguished by repetitive complications and pregnancy loss in the absence of definite …
Article scientifique
Association of inherited thrombophilia mutations and their combinations among palestinian women with unexplained recurrent miscarriage
BACKGROUND: Inherited thrombophilia (IT) has a complex pathophysiology and is associated with recurrent miscarriage (RM) by causing placental insufficiency and …
Article scientifique
The magnitude and associated factors of coagulation abnormalities among liver disease patients at the University of Gondar Comprehensive Specialized Hospital Northwest, Ethiopia, 2022
BACKGROUND: Liver disease is any condition that affects the liver cells and their function. It is directly linked to coagulation …
Article scientifique
Serum interleukin 1β and sP-selectin as biomarkers of inflammation and thrombosis, could they be predictors of disease severity in COVID 19 Egyptian patients? (a cross-sectional study)
BACKGROUND: Thromboembolism was a chief cause of mortality in 70% of patients with COVID-19. Our objective was to see if …
Article scientifique
Anticoagulation control, outcomes, and associated factors in long-term-care patients receiving warfarin in Africa: a systematic review
BACKGROUND: Oral anticoagulation therapy with warfarin requires frequent monitoring level of anticoagulation by the international normalized ratio (INR). In Africa, …
Article scientifique
Testing P2Y12 platelet inhibitors generics beyond bioequivalence: a parallel single-blinded randomized trial
Cardiovascular diseases are the leading cause of death worldwide. Ticagrelor is an oral antiplatelet drug used in acute coronary syndrome. …
Article scientifique
The evolution of clot strength in critically-ill COVID-19 patients: a prospective observational thromboelastography study
BACKGROUND: Few studies detail the evolution of COVID-19 associated coagulopathy. We performed serial thromboelastography (TEG) and laboratory coagulation studies in …
Article scientifique
Incidence of peripheral intravenous catheter phlebitis and its associated factors among patients admitted to University of Gondar hospital, Northwest Ethiopia: a prospective, observational study
BACKGROUND: Phlebitis, inflammation of tunica intima of venous wall, occurred in 13-56% of hospitalized patients. It is characterized by pain, …
Article scientifique
Coagulation abnormalities in childhood acute lymphoblastic leukemia: assessing the impact of L-asparaginase therapy in Ghana
BACKGROUND: Although the rate of childhood acute lymphoblastic leukemia (ALL) is increasing in Africa, there is a dearth of information …
Article scientifique
Coagulopathy and its associated factors among patients with a bleeding diathesis at the University of Gondar Specialized Referral Hospital, Northwest Ethiopia
BACKGROUND: Coagulopathy is the major cause of mortality and morbidity throughout the world. Globally, about 26-45% of healthy people have …
Article scientifique
The association of alcohol with circulating total fibrinogen and plasma clot density is mediated by fibrinogen and FXIII genotypes
BACKGROUND: Alcohol consumption is associated with haemostasis and so may influence cardiovascular conditions. It is unknown whether the association of …
Article scientifique
Thrombotic thrombocytopenic purpura (TTP)-like syndrome in the HIV era
BACKGROUND: The thrombotic microangiopathies (TMAs) is a heterogeneous group of relatively uncommon but serious disorders presenting with thrombocytopenia and microangiopathic …
Article scientifique
Combination of acquired von Willebrand syndrome (AVWS) and Glanzmann thrombasthenia in monoclonal gammopathy of uncertain significance (MGUS), a case report
BACKGROUND: Autoimmune paraphenomena, are associated with B-cell lymphoproliferative disorders, including monoclonal gammopathy of uncertain significance. These paraphenomena can rarely include …
Article scientifique
Sickle cell disease, sickle trait and the risk for venous thromboembolism: a systematic review and meta-analysis
Globally, sickle cell disease (SCD) is one of the most common haemoglobinopathy. Considered a public health problem, it leads to …
Article scientifique
Poor outcomes associated with antithrombotic undertreatment in patients with atrial fibrillation attending Gondar University Hospital: a retrospective cohort study
BACKGROUND: Atrial fibrillation (AF) is a major risk factor for stroke as it increases the incidence of stroke nearly fivefold. …
Article scientifique
Human blood platelets and viruses: defense mechanism and role in the removal of viral pathogens
Platelets are small non-nucleated cell fragments and the second most abundant cell that play crucial role in managing vascular integrity …
Article scientifique
Effects of Ramadan fasting on platelet reactivity in diabetic patients treated with clopidogrel
BACKGROUND: The effects of Ramadan fasting (RF) on clopidogrel antiplatelet inhibition were not previously investigated. The present study evaluated the …