846 publication(s) trouvée(s)
Article scientifique
Development of Eudragit/gelatin-based microparticles for oral insulin delivery for diabetes treatment
Purpose: To prepare Eudragit® S100/gelatin-based insulin-loaded microparticles for improved oral delivery of insulin in diabetes management. Methods: Eudragit® S100 and …
Article scientifique
Use of technology in undergraduate pharmacy education in selected universities in southern Nigeria
Purpose: To explore the technologies used in pharmacy education for teaching by lecturers and learning by students in selected universities …
Article scientifique
Terminalia avicennioides root bark extract: A promising phytotherapeutic agent against methicillin-resistant Staphylococcus aureus hospital strains
Purpose: To investigate the antibacterial activity of a partially purified ethyl acetate fraction obtained from methanol extract of the root …
Article scientifique
Keratin/alginate microspheres as a novel pH-dependent polymer for colon-targeted delivery of dexamethasone for the management of inflammatory bowel disease
Purpose: To develop keratin/alginate microspheres loaded with dexamethasone for managing inflammatory bowel disease (IBD), enabling targeted delivery to the colon …
Article scientifique
Histopathological evaluation of D’General Bitters on renal health in adult male Wistar rats
Purpose: To evaluate the potential nephrotoxic effects of D’General Bitters through histopathological analysis.Methods: A total of 32 male Wistar rats …
Article scientifique
Analysis of chitosan nanoparticles synthesized from cowry and oyster shell byproducts using Cymbopogon citratus and silver nitrate
Purpose: To determine the properties of chitosan nanoparticles synthesized from Cymbopogon citratus and silver nitrate (AgNO3).Methods: Chitosan nanoparticles (CNPs) were …
Article scientifique
Encapsulation of aceclofenac hydrogel-based solid dispersion for sustained delivery
Purpose: To develop aceclofenac hydrogel-based solid dispersions (AC-HSDs) encapsulated in two modified gelatin capsules (MGCs as MGX1 and MGX2) for …
Article scientifique
Behavioural alterations and cerebellar toxicity induced by Datura metel exposure in mice
Purpose: To investigate the neurotoxic effects of methanolic crude extract of leaves of Datura metel L. Solanaceae on the cerebellum …
Article scientifique
Predicting cosolvents, surfactants and electrolytes as potential transdermal delivery enhancers of pantoprazole
Purpose: To predict cosolvents, surfactants, and electrolytes as potential enhancers of pantoprazole transdermal delivery by examining their effects on the …
Article scientifique
Development and characterization of Soluplus-based solid dispersion to improve solubility
Purpose: To improve the solubility of lumefantrine (lum), using developed solid dispersions (SDs) with Soluplus and Kollidon VA 64, at …
Article scientifique
Histopathological effects of D’General Bitters on the pancreas of male adult Wistar rats
Purpose: To investigate the histopathological effect of D’General Bitters (a herbal drink) on the pancreas of adult male Wistar rats. …
Article scientifique
Evaluation of ssDNA aptamer binding to Aurora Kinase A and its cytotoxic effects on HeLa and MCF-7 cancer cell lines
Purpose: To investigate the binding potential of ssDNA aptamer to Aurora kinase A (AURKA) and assess its inhibitory effect on …
Article scientifique
Phytolipid delivery of Pentaclethra macrophylla (Fabaceae) extract: In vitro and in vivo activities
Purpose: To investigate the physicochemical properties and in vivo anti-inflammatory activity of phytosome complexes prepared from Pentaclethra macrophylla seeds. Method: …
Article scientifique
Study of two lactases for the manufacture of lactose-free yogurt by K-Lolac enzymatic method
Purpose: To investigate the efficiency of two lactase enzymes in producing lactose-free yogurt. Methods: Two lactase enzymes (NOLA™5500 fit and …
Article scientifique
Environmental impact of crude oil on the phytochemical constituents of some selected medicinal plants in Nigeria
Purpose: To investigate the effect of crude oil exploration on secondary metabolites of Magnifera indica, Ficus exasperata, Mallotus oppositifolius, Millettia …
Article scientifique
Combination of melatonin and chondroitin sulphate provides better chondroprotection in osteoarthritis in male Wistar rats
Purpose: To investigate the effect of melatonin (MEL) and chondroitin sulphate (CHS) in osteoarthritis (OA) in male Wistar rats. Methods: …
Article scientifique
Antiplasmodial and antitrypanosomal effects of some plant extracts utilized within Nigerian traditional healing practices
Purpose: To investigate the antiplasmodial and antitrypanosomal properties of extracts from Anthocleista djalonensis A. Chev. (Gentianaceae), Vernonia cinerea Less (Asteraceae), …
Article scientifique
Isolation and evaluation of the antibacterial constituents of Synsepalum brevipes
Purpose: To isolate and evaluate the antibacterial constituents of Synsepalum brevipes.Methods: The compounds were isolated using varying chromatographic separation methods. …
Article scientifique
Monitoring the quality of quinine injection in retail outlets in south-east Nigeria
Purpose: To determine the pharmaceutical quality of quinine injections sold in retail outlets in SouthEast Nigeria.Methods: Eleven brands of 2 …
Article scientifique
Inhibitory effect of Siphonochilus aethiopicus (Schweinf.) B.L. Burtt on prostaglandin/leukotrienes synthesis, and in silico analysis of HPLC-identified compounds
Purpose: To investigate the lipoxygenase (LOX) and cyclooxygenase (COX) inhibitory effects of Siphonochilus aethiopicus (Schweinf) B.L. Burtt (Zingiberaceae) rhizome, and …