846 publication(s) trouvée(s)
Article scientifique
Formulation of keratin/HPMC matrix tablets for sustained delivery of diclofenac potassium for the management of inflammation
Purpose: To investigate the excipient properties of keratin/HPMC in sustained-release diclofenac matrix tablets.Method: Tablets were prepared by wet granulation using …
Article scientifique
Comparative effect of chronic administration of artemether/lumefantrine and chloroquine on selected male reproductive indices
Purpose: To evaluate the effect of administration of artemether/lumefantrine and chloroquine on some male reproductive parameters. Methods: Sixty adult male …
Article scientifique
Effect of chitosan-silver nanoparticle composite-treated water on selected biochemical parameters of rats
Purpose: To investigate the impact of chitosan-silver nanoparticles (chitosan-AgNP) composite-treated water on some biochemical parameters in the albino rats. Methods: …
Article scientifique
Pharmacognostic, phytochemical, antioxidant and toxicological properties of aqueous extract of Telfairia occidentalis Hook. F. leaves
Purpose: To determine the phytochemical composition, toxicological profile, pharmacognostic and therapeutic potential of aqueous extract of Telfairia occidentalis (T. occidentalis) …
Article scientifique
Structural and functional response of the genital tract to paraquat (PQ) dichloride exposure in female Wistar rats
Purpose: To investigate the structural and functional response of genital tract to paraquat (PQ) exposure in female Wistar rats. Methods: …
Article scientifique
Phytochemical profiling and bioactive compound variation in Jatropha landraces from Nigeria: Implications for agricultural and medicinal applications
Purpose: To determine the phytochemical composition of various Jatropha landraces from different regions of Nigeria in order to identify key …
Article scientifique
Cytotoxicity of Diospyros dichrophylla extracts on breast and brain cancer cell lines
Purpose: To examine the cytotoxic properties of different parts of Diospyros dichrophylla on breast and brain cancer cell lines. Methods: …
Article scientifique
Post-market monitoring of efficacies and determination of acid-neutralizing capacity of some antacid formulations in Nigeria
available in Nigeria by evaluating the acid-neutralizing capacities (ANCs) of 28 antacid brands. Methods: The active pharmaceutical ingredients (APIs) were …
Article scientifique
Therapeutic potential of methanol extracts of Calocybe indica (mushroom) on cadmium chloride-induced hepato-renal toxicity in rats
Purpose: To investigate the efficacy of Calocybe indica extract (CIE) in alleviating liver and kidney toxicity caused by cadmium chloride …
Article scientifique
Isolation and characterization of terrestrial Streptomyces strains with antimicrobial and anti-ulcer activities
Purpose: To determine the antimicrobial, anti-ulcer and cytotoxic activities of secondary metabolites isolated from Streptomyces spp in soil samples obtained …
Article scientifique
Lumefantrine-neusilin® based amorphous multicomponent solid dispersion: In vivo and in vitro characterization
Purpose: To develop Neusilin-based amorphous multi-component solid dispersions (NAM-SDs) to improve poor aqueous solubility, low bioavailability and absorption of lumefantrine …
Article scientifique
Antiplasmodial and cytotoxic activities of Jussiaea linifolia G. Don extracts
Purpose: To evaluate the in vivo and in vitro antiplasmodial activity of Jussiaea linifolia extracts using validated models.Methods: Methanol extract …
Article scientifique
Multidisciplinary telehealth interventions for autistic children in sub-Saharan Africa: challenges and recommendations
History of autism is plagued by misconceptions and distortions and it is mostly attributed to spiritual causes. A comprehensive literature …
Article scientifique
Telemedicine promise for tomorrow: The role of video synchronous medical consultation in a primary health center (PHC) in a sub-Saharan Africa setting
Purpose: To demonstrate the use of telemedicine electronic communications to exchange medical information from one site to another to improve …
Article scientifique
Growth optimizatio n and metabolite yield of non pathogenic Escherichia coli isolated from the gut of African catfish: Clarias gariepinus
Purpose: To investigate the optimum growth and metabolite yield of non-pathogenic Escherichia coli in the gut of African catfish for …
Article scientifique
Serum levels of copper and zinc and their relationship with iron status in sickle cell anemia patients
Purpose: To determine the serum levels of copper and zinc and their relationship with iron status in patients with sickle …
Article scientifique
Toxicological evaluation of hydro-alcohol root extract of Rauwolfia vomitoria Afzel (Apocynaceae)
Purpose: To investigate the phytochemical content and toxicity profile of Rauwolfia vomitoria Afze (Apocynaceae). Method: Qualitative phytochemical screening of hydro-alcohol …
Article scientifique
Uterotrophic bioassay of Carica papaya and Garcinia kola (bi-herbal) aqueous extract
Purpose: To investigate the estrogenic effect of Carica papaya, Garcinia kola, bi-herbal (BH) using the uterotrophic assay. Methods: Twenty-five (25) …
Article scientifique
Memory-enhancing activity of verapamil in murine models of stress
Purpose: To evaluate the benefit of verapamil on stress-induced memory impairment in mice. Methods: Forty-eight (48) mice were used in …
Article scientifique
Assessment of organ weight changes in normal and streptozotocin-induced diabetic rats treated with Olea europaea L. leaf extract
Purpose: To evaluate the antidiabetic activity of crude extract of Olea europaea L. (CEOE) leaves in streptozotocin induced-diabetic rats and …