Sciences de la santé

Article scientifique

The vaccination paradox: how East Africa’s success in Ebola vaccine preparedness may be creating new public expectations for future outbreaks

This perspective synthesizes published evidence on Ebola vaccination and outbreak preparedness in Africa. Successful vaccination against Zaire ebolavirus has strengthened …

2026 Open Access

Article scientifique

Youth access and utilization of HIV services in Homa Bay, Kenya: protocol for a mixed-methods study

Background Youth aged 15–24 years continue to experience substantial HIV-related vulnerability, particularly in sub-Saharan Africa. Although HIV prevention, testing, treatment …

2026 Open Access

Article scientifique

Pushed, Pulled, and Moored: A Systematic Review and Meta-analysis of Migration Intentions Among Medical Trainees in the Arab Region

INTRODUCTION: The Arab region is experiencing substantial outward migration amid persistent healthcare workforce shortages. However, reported prevalence estimates and reasons …

2026 Open Access

Article scientifique

Impact of seven conservation methods on the nutritional value, phytochemical composition, and chemical antioxidant capacity of Terfezia boudieri and Tirmania nivea from Southeastern Tunisia

Introduction Desert truffles ( Terfezia boudieri and Tirmania nivea ) are edible fungi valued for their nutritional and nutraceutical properties. …

2026 Open Access

Article scientifique

Digital mobility assessment using wearable devices in people with Parkinson’s disease: a feasibility and implementation study in Ghana (TraPCAf) compared with a UK cohort

Introduction Life expectancy is rising in Africa, increasing Parkinson’s disease (PD) prevalence. PD in Africa is often underdiagnosed/undertreated due to …

2026 Open Access

Article scientifique

Regional and socioeconomic inequalities and factors associated with low birth weight in Ghana: a multilevel analysis of the 2022 Ghana Demographic and Health Survey

Introduction Low birth weight (LBW) remains a major public health challenge globally, particularly in low- and middle-income countries (LMICs). In …

2026 Open Access

Article scientifique

Evaluating smartphone-based cough frequency monitoring for tuberculosis screening and triage in Uganda: A mixed-methods evaluation

Symptom-based tuberculosis screening usually depends on self-reported cough, which is subjective. Passive smartphone cough monitoring offers a more objective alternative. …

2026 Open Access

Article scientifique

SARS-CoV-2 neutralising antibody profiles reveal variant specific antibody dynamics and regional differences in infection histories in Malawi

Serological data provide important insights into SARS-CoV-2 transmission and immunity, particularly in regions with limited routine surveillance such as sub-Saharan …

2026 Open Access

Article scientifique

Time to death and predictors of in-hospital mortality among adults underwent emergency abdominal surgery at a tertiary hospital in Ethiopia: a retrospective follow-up study

Abstract Emergency abdominal surgery is burdened by significant mortality and morbidity rates. There is a short window between the time …

2026 Open Access

Article scientifique

Life expectancy nexus mortality in 14 selected SADC countries with trend analysis

Abstract Background This study provides a dimensional analysis of the nexus between life expectancy and mortality-related indicators across 14 Southern …

2026 Open Access

Article scientifique

Fear of Ebola and willingness to work during an Ebola outbreak among healthcare workers in a non-affected city of the Democratic Republic of the Congo

2026 Open Access

Article scientifique

The influence of playing surface quality and centralized venue transitions on match performance and non-contact injury incidence in the ethiopian premier league

2026 Open Access

Article scientifique

From detection to response: a critical narrative review of infectious disease surveillance and outbreak preparedness in Somalia

Infectious disease surveillance and outbreak preparedness are essential to health security, yet maintaining these functions remains difficult in fragile and …

2026 Open Access

Article scientifique

Parasitological efficacy of sulfadoxine-pyrimethamine and amodiaquine for seasonal malaria chemoprevention in Africa

Abstract Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) protects millions of African children, yet the contribution of each …

2026 Open Access

Article scientifique

Stochastic dynamics of oxygen-hemoglobin binding: insight through facilitated exploration of an agent-based model

Background Understanding oxygen–hemoglobin binding is fundamental to physiology and clinical practice. However, most students have an exclusively deterministic view of …

2026 Open Access

Article scientifique

Rapid diagnosis of pulmonary tuberculosis on induced sputum in children in a high burden setting for HIV and malnutrition

Microbiological diagnosis of childhood pulmonary tuberculosis can be challenging. We investigated the accuracy of Xpert MTB/RIF Ultra on the induced …

2026 Open Access

Article scientifique

Stakeholder perspectives on adolescent sexual and reproductive health service utilization in Uganda’s Busoga region: A qualitative study

BACKGROUND: Adolescents in low- and middle-income countries face high rates of unintended pregnancy, sexually transmitted infections (STIs), and unmet sexual …

2026 Open Access

Article scientifique

Unveiling the role of circulating monocyte-macrophage polarization state and PD-L1/PD-L2 expression in newly diagnosed pediatric ITP

BACKGROUND: Immune thrombocytopenia (ITP) is an immune-mediated disorder characterized by decreased platelet count resulting from immune dysregulation and altered cellular …

2026 Open Access

Article scientifique

Microfilaremic loiasis is associated with T cell hyporesponsiveness against SARS-CoV-2

BACKGROUND: Loiasis is a chronic filarial infection endemic to Central and West Africa. Although long considered benign, increasing evidence links …

2026 Open Access

Article scientifique

Co-occurrence of anaemia and malaria among children under five in Uganda: A joint modeling analysis

Childhood illnesses such as anaemia and malaria continue to pose significant health risks for children under five in sub-Saharan Africa. …

2026 Open Access