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71477 publication(s) trouvée(s)
Article scientifique
Variation in neutrophil levels and artemisinin-based combination therapy efficacy in West-Africa
INTRODUCTION: Polymorphonuclear neutrophils (PMN) are involved in pathogen clearance by phagocytosis. However, the role of PMNs in the efficacy of …
Article scientifique
Cultural barriers to male partners’ involvement in antenatal care in Limpopo province
Background: Participation of male partners in antenatal care (ANC) is a complicated process that involves social and behavioural transformation. It …
Article scientifique
Assessing HLA imputation accuracy in a West African population
The Human Leukocyte Antigen (HLA) region plays an important role in autoimmune and infectious diseases. HLA is a highly polymorphic …
Article scientifique
Therapeutic efficacy of β-sitosterol treatment on Trypanosoma congolense infection, anemia development, and trans-sialidase (TconTS1) gene expression
Background African animal trypanosomiasis hinders sustainable livestock productivity in sub-Saharan Africa. About 17 million infected cattle are treated with trypanocides …
Article scientifique
Molecular Characterization of Erythrocyte Glucose-6-Phosphate Dehydrogenase Deficiency in Different Ethnic Groups of Blood Donors in Mauritania
Background: Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is the most frequent enzymopathy worldwide; it is a genetic disorder that affects red blood cells …
Article scientifique
Genetic variation in environmental enteropathy and stunting in Zambian children: A pilot genome wide association study using the H3Africa chip
PURPOSE: Stunting is known to be heavily influenced by environmental factors, so the genetic contribution has received little attention. Here …
Article scientifique
Examining comorbidities in children with diarrhea across four provinces of Mozambique: A cross-sectional study (2015 to 2019)
Comorbidities are defined as the simultaneous occurrence of two or more diseases within the same individual. Comorbidities can delay a …
Article scientifique
The cardioprotective effect of S. africana caerulea/Blue Sage in ischaemia and reperfusion induced oxidative stress
Background: Since antiquity, alternative herbal remedies, such as S. africana caerulea/Blue Sage (BLS) water infusion extract (WIE) has been used …
Article scientifique
Evaluation of the Emergency Obstetric and Newborn Care training in Gondar, Ethiopia; a mixed methods study
In Ethiopia maternal and perinatal morbidity and mortality remains high. Timely access to quality emergency obstetric and neonatal care is …
Article scientifique
Learning from implementation of a COVID case management desk guide and training: a pilot study in Sierra Leone
BACKGROUND: When the COVID pandemic hit the world, there was need for applied guides and training materials to support frontline …
Article scientifique
Effect of intravenous dexamethasone on the duration of hyperbaric bupivacaine spinal anesthesia in lower abdominal surgery, Randomized controlled trial
BACKGROUND: The purpose of this study was to investigate the effect of intravenous (IV) dexamethasone on the duration of hyperbaric …
Article scientifique
Incident Kaposi sarcoma during the expansion of antiretroviral therapy eligibility in Nigeria: a retrospective cohort study
INTRODUCTION: The expansion of antiretroviral therapy (ART) eligibility could lead to earlier initiation of Human Immunodeficiency Virus (HIV) treatment and …
Article scientifique
Risk factors associated with acute kidney injury in a pediatric intensive care unit in Addis Ababa Ethiopia: case-control study
BACKGROUND: Acute kidney injury (AKI) is a serious health problem in critically ill children. It is associated with poor treatment …
Article scientifique
Predictors of underweight among adult patients receiving antiretroviral therapy in Bishoftu general hospital, central Ethiopia: Case-control study
BACKGROUND: Underweight affects the overall clinical outcome and quality of life and increases the risk of mortalities in Human immunodeficiency …
Article scientifique
Mapping global evidence on injuries/trauma due to sexual and gender-based violence for research prioritisation and development of guidelines to mitigate their impact: a scoping review protocol
BACKGROUND: The World Health Organization recognises injuries as a growing global public health problem. While there are several causes of …
Article scientifique
Understanding sexual behaviors of youth from the lens of caregivers, teachers, local leaders and youth in Homabay County, Kenya
In Kenya similar to other countries in Eastern and Southern Africa There is a disproportionately high burden of the global …
Article scientifique
Malaria rapid diagnostic tests in community pharmacies in Rwanda: availability, knowledge of community pharmacists, advantages, and disadvantages of licensing their use
Abstract Background Presumptive treatment of malaria is often practiced in community pharmacies across sub-Saharan Africa (SSA).To address this issue, the …
Article scientifique
Alcohol intake, smoking, self-medication practices and burden of anaemia among traders in Tamale metropolis of Ghana
Abstract Objective Lifestyle choices including physical inactivity, smoking, abuse of alcohol and drugs, unhealthy diet are common among traders and …
Article scientifique
Do pregnant African women exercise? A meta-analysis
INTRODUCTION: Antenatal exercise can reduce gestational weight gain, backache; pregnancy induced medical disorders, caesarean section rates, and improves pregnancy outcomes. …
Article scientifique
Healthcare provider and drug dispenser knowledge and adherence to guidelines for the case management of malaria in pregnancy in the context of multiple first-line artemisinin-based combination therapy in western Kenya
BACKGROUND: Concerns about emerging resistance to artemether-lumefantrine (AL) in Africa prompted the pilot introduction of multiple first-line therapies (MFT) in …