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71302 publication(s) trouvée(s)
Article scientifique
Antiproliferation, 3D-multicellular spheroid and VEGFR-2 inhibitory properties of spiroindolin-2-ones with phosphonate function
Abstract Spiroindolin-2-ones with phosphonate function 17a‒t (20 analogs, 96‒72% yield) were generated by microwave synthetic methodology using azomethine cycloaddition of …
Article scientifique
The rising burden of female cancer in Ethiopia (2000–2021) and projections to 2040: Insights from the global burden of disease study
BACKGROUND: Female cancers-breast, cervical, ovarian, and uterine-pose significant public health and socio-economic challenges, particularly in low- and middle-income countries like …
Article scientifique
Lupus nephritis in Africa: a systematic review of case reports and case series
BACKGROUND: Lupus nephritis remains a severe manifestation of systemic lupus erythematosus across African populations, where diagnostic and therapeutic challenges significantly …
Article scientifique
Article antidiabetic potential of peanut oil: inhibiting α-amylase and α-glucosidase using identified phytochemicals through in vitro and in silico studies
Background Peanut oil is recognized for its mild flavor, high phytochemical content, medicinal potential, and other health advantages. Objective This …
Article scientifique
Efficacy of Vector Guard®, a mosaic alpha-cypermethrin and piperonyl butoxide-treated net, for the control of pyrethroid-resistant malaria vectors: a non-inferiority experimental hut evaluation in Benin
BACKGROUND: Insecticide-treated nets (ITNs) incorporating pyrethroids with piperonyl butoxide (PBO) have demonstrated enhanced effectiveness against malaria transmitted by pyrethroid-resistant vectors …
Article scientifique
Prevalence and impact of thyroid dysfunction in patients with rheumatoid arthritis
Thyroid disorders are common in patients with autoimmune diseases such as rheumatoid arthritis (RA). Both conditions present significant public health …
Article scientifique
Targeted liposomal nano-therapy combining anthocyanin and cisplatin reduces Ehrlich ascites carcinoma burden
Background: Ehrlich ascites carcinoma (EAC), a rapidly growing tumor model, poses challenges in chemotherapy due to toxicity and resistance. Liposomal …
Article scientifique
Case Report: Dual molecular diagnosis of gain-of-function STAT1 mutation and regulatory STAT3 variant in a patient with a hyper-IgE-like phenotype
Background The transcription factors signal transducer and activator of transcription 1 and 3 (STAT1 and STAT3) play essential roles in …
Article scientifique
“I wish someone else could notify the partner”: barriers to STI partner notification identified and experienced by young women and health care workers in Cape Town, South Africa
Background: South African clinical guidelines for sexually transmitted infections (STI) treatment and management recommend that all individuals who test positive …
Article scientifique
Complete genome sequencing, molecular and antigenic characterization of duck hepatitis A virus type 1 isolated in Benha, Egypt
BACKGROUND: Duck virus hepatitis (DVH) is highly fatal disease that predominantly affects young ducklings, causing substantial losses due to its …
Article scientifique
Current knowledge and attitudes toward antibiotic use among community pharmacy personnel in a rural province in South Africa and the implications
Background Antimicrobial resistance (AMR) is an appreciable threat to public health, especially among low- and middle-income countries (LMICs), exacerbated by …
Article scientifique
Advancing institutionalization and sustainability of field epidemiology training programs in the Eastern Mediterranean region
Introduction: Sustaining Field Epidemiology Training Programs (FETPs) is critical for long-term public health capacity. Institutionalization-embedding programs within national health systems-is …
Article scientifique
Predicting treatment adherence in patients with drug-resistant tuberculosis: insights from socioeconomic, demographic, and clinical factors of patients in the rural Eastern Cape
Background: Drug-resistant tuberculosis (DR-TB) poses a serious challenge to global health. Patients must follow complex medication regimens over long periods, …
Article scientifique
Nationwide surveillance detects yellow fever and chikungunya viruses in multiple Aedes mosquito species in Nigeria
BACKGROUND: Since the reemergence of yellow fever in 2017, the Nigeria Centre for Disease Control (NCDC) has been coordinating responses …
Article scientifique
Unraveling the relationship between nutritional status, cognitive function, and school performance among school-aged children in Taabo, Côte d'Ivoire: a school-based observational study
Background Nutritional deficiencies are one of the main factors that affect cognitive development. In Côte d'Ivoire, although nutritional deficiencies have …
Article scientifique
Dysmenorrhea among working women and its effect on their work productivity and activity impairment
BACKGROUND: Dysmenorrhea, or painful menstruation, is a common condition among women of reproductive age, significantly hindering their ability to work …
Article scientifique
Assessment of MgO, ZnO, chitosan hydroxyapatite and silver hydroxyapatite nanoparticles against carbapenem-resistant Gram-negative Egyptian clinical isolates: a combined in-silico and in-vitro study
BACKGROUND: Currently, antimicrobial resistance (AMR) is one of the major global threats to public health; therefore, treating infectious diseases becamemore …
Article scientifique
Enhanced myco-synthesis of selenium and zinc oxide nanoparticles and evaluating their anticancer activities and role against antibiotic resistance genes in certain bacterial strains
BACKGROUND: In an array to check microbial resistance against generally used antibiotics, it is essential to create innovative and efficient …
Article scientifique
Traditional medicine, environmental exposures, and cultural practices in cancer risk: insights from low- and middle-income countries
Cancer is a growing public health concern in low- and middle-income countries (LMICs), influenced by cultural practices, environmental exposures, and …
Article scientifique
Harnessing traditional healers role in strengthening Africa’s public health response: A case study of Mpox outbreak
Mpox, a zoonotic viral disease endemic in Central and West Africa, has posed major public health challenges, particularly following the …