71302
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71302 publication(s) trouvée(s)
Article scientifique
Role of vitamin D as adjuvant therapy on multiple sclerosis: an updated systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Multiple sclerosis (MS) is the most common demyelinating disorder affecting the central nervous system, with multiple risk factors suggested …
Article scientifique
One-hour extraction-free loop-mediated isothermal amplification HPV DNA assay for point-of-care testing in Maputo, Mozambique
Human papillomavirus (HPV) is responsible for nearly all cases of cervical cancer. Affordable point-of-care DNA testing is needed for cervical …
Article scientifique
Opioid-sparing multimodal analgesia for post-craniotomy pain: a randomized, double-blind, placebo-controlled trial
BACKGROUND: Postoperative pain control in neurosurgical patients particularly after elective craniotomy remains clinically challenging due to the need for early …
Article scientifique
Optimizing antithrombotic therapy following mitral valve repair: a comprehensive network meta-analysis
BACKGROUND: Mitral regurgitation (MR) presents either as primary or secondary, with options for surgical or transcatheter repair. Thromboembolic risks following …
Article scientifique
HOMA-IR, an independent predictor of advanced liver fibrosis in metabolic-dysfunction associated fatty liver disease: a cross-sectional study in Egyptian patients
While metabolic dysfunction-associated fatty liver disease (MAFLD) includes the homeostatic model assessment for insulin resistance (HOMA-IR) as one of the …
Article scientifique
Practices and challenges of supervision and delegation in nursing in Africa: a scoping review
BACKGROUND: Nursing supervision and delegation are essential components of healthcare delivery, significantly impacting patients' care and outcomes. In low-resource settings, …
Article scientifique
Synbiotic yogurt with nanoparticle entrapped rice straw hemicellulose for immediate probiotic support and prebiotic delivery
This study presents a novel synbiotic yogurt fortified with free and PLGA-entrapped rice straw hemicellulose hydrolyzate (RSHH) to offer immediate …
Article scientifique
Bayesian spatio-temporal modeling and prediction of malaria cases in Tanzania mainland (2016-2023): unveiling associations with climate and intervention factors
Abstract Background Malaria continues to pose a significant global health challenge, affecting approximately 200 million individuals annually and resulting in …
Article scientifique
Predicting cancer risk using machine learning on lifestyle and genetic data
Cancer remains one of the leading causes of mortality worldwide, where early detection significantly improves patient outcomes and reduces treatment …
Article scientifique
Tenecteplase versus alteplase in patients with acute ischemic stroke: an updated systematic review and meta-analysis
BACKGROUND: Stroke was the second leading cause of death and the third leading cause of disability worldwide in 2019. Alteplase …
Article scientifique
Psychosocial and quality of life assessment in kidney transplant recipients: a focus on anxiety, depression, and clinical correlates
BACKGROUND: Kidney transplantation (KT) significantly improves survival and quality of life compared to dialysis, yet psychological disorders like anxiety and …
Article scientifique
Bacterial cellulose doped with ZnO as a multifunctional bioactive platform for curcumin and propolis immobilization: synthesis, characterization, and wound healing potential
Bacterial cellulose (BC)-based dressings exhibit favorable hydrogel characteristics, including high biocompatibility, moisture regulation, and mechanical adaptability, making them suitable candidates …
Article scientifique
Improved pulmonary embolism detection in CT pulmonary angiogram scans with hybrid vision transformers and deep learning techniques
Pulmonary embolism (PE) represents a severe, life-threatening cardiovascular condition and is notably the third leading cause of cardiovascular mortality, after …
Article scientifique
Exosome mediated delivery of Epigallocatechin 3 gallate as a novel approach to alleviate psoriasis symptoms through cytokine and apoptotic pathway modulation
Psoriasis is a chronic skin disorder with significant individual and societal impacts. Current therapies often lack efficacy, are costly, or …
Article scientifique
Selenium nanoparticle loaded on PVA/chitosan biofilm synthesized from orange peels: antimicrobial and antioxidant properties for plum preservation
This study investigates the eco-friendly synthesis, characterization, and biological activity of selenium nanoparticles (SeNPs) incorporated into a polyvinyl alcohol/chitosan (PVA/CH) …
Article scientifique
GLP-1 receptor agonists in Parkinson’s disease: an updated comprehensive systematic review with meta-analysis
Abstract Previous studies have demonstrated an increased risk of developing Parkinson’s disease (PD) in patients with type 2 diabetes mellitus …
Article scientifique
Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019–2024
Abstract The treatment and control of malaria in Africa is challenged by drug resistance. We characterized ex vivo susceptibilities to …
Article scientifique
Revamping Parkinson’s disease therapy using PLGA-based drug delivery systems
Parkinson's Disease (PD) involves degeneration of dopamine-producing neurons, mitochondrial dysfunction, alpha-synuclein aggregation, neuroinflammation, and gut-brain axis disturbances. Despite the availability …
Article scientifique
Community Health Worker-led versus facility-based hypertension care for people with uncontrolled blood pressure in rural Lesotho: a cluster-randomized trial within the ComBaCaL cohort study
Article scientifique
The Fate of Participants Excluded from Clinical Trials, Case of the New Antiretroviral and Monitoring Strategies in HIV-infected Adults in Low-income Countries (NAMSAL) Study: A Retrospective Cohort Study in Yaoundé (Cameroon)