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817 publication(s) trouvée(s)
Article scientifique
Risk factors associated with Shigella diarrhea in 6-35-month-olds: A Cross-Sectional Study, Malawi, 2022-2024
Abstract Diarrhea due to Shigella causes 60,000 deaths annually among children under five in low- and middle-income countries. This Enterics …
Article scientifique
Depression and its associated factors among people who use drugs attending the Methadone Treatment Clinic at Tumbi Hospital in Pwani, Tanzania: A cross-sectional study
Opioid use disorder is a major global health concern. While methadone treatment is effective in treating opioid use disorder, individuals …
Article scientifique
Safety, tolerability, and immunogenicity of INO-4500, a synthetic DNA-based vaccine against Lassa virus, in a phase 1b clinical trial in healthy Ghanaian adults
Background: Lassa fever (LF) is an acute viral hemorrhagic illness endemic to West Africa, with no licensed vaccines or targeted …
Article scientifique
ABO blood groups and cardiovascular disease and its risk in continental Africans and people of African ancestry: A systematic review
BACKGROUND: Cardiovascular disease (CVD) remains a global health challenge and contributes substantially to mortality burden in sub-Saharan Africa (SSA) in …
Article scientifique
Multilingual voice-enabled informatics tools: Catalyst for equitable AI in HIV and HIV-comorbidity healthcare management
Human Immunodeficiency Virus (henceforth HIV) is a global health problem, presently with no known cure. Africa has one of the …
Article scientifique
Exploring behavioral determinants of antimicrobial dispensing in drug retail outlets of Addis Ababa, Ethiopia: a mixed methods study
Antimicrobial resistance (AMR) is a critical global health threat, exacerbated by inappropriate dispensing practices. Despite efforts to improve antimicrobial stewardship, …
Article scientifique
Advancing cervical cancer treatment: integrating cannabinoids, combination therapies and nanotechnology
BACKGROUND: Cervical cancer remains a major global health challenge, with the highest incidence and mortality rates observed in sub-Saharan Africa. …
Article scientifique
Predicting treatment adherence in patients with drug-resistant tuberculosis: insights from socioeconomic, demographic, and clinical factors of patients in the rural Eastern Cape
Background: Drug-resistant tuberculosis (DR-TB) poses a serious challenge to global health. Patients must follow complex medication regimens over long periods, …
Article scientifique
Mentorship—A critical metric for career development and advancing global health
Mentorship plays a critical role in promoting career development and generating impactful research and programs, yet it is typically considered …
Article scientifique
Knowledge, attitude, and quality of life among newly diagnosed type 2 diabetic patients attending diabetic clinics at Bugando Medical Centre, Mwanza, Tanzania
Background: Diabetes mellitus, particularly type 2 diabetes, is a rapidly escalating global health issue. The World Health Organization projects a …
Article scientifique
Prevalence, types, and determinants of intimate-partner violence among pregnant women in Northern Uganda: a hospital-based cross-sectional study
BACKGROUND: Intimate partner violence (IPV) against women is a global health issue, affecting one in three women worldwide. Exposure to …
Article scientifique
Navigating socio-ecological and institutional barriers to antiretroviral therapy adherence: qualitative insights among young men and women from Nairobi’s informal settlements
Background The Human Immunodeficiency Virus (HIV) and acquired immunodeficiency syndrome (AIDS) pandemic remains a major global health issue, with 40.8 …
Article scientifique
Global Health Education in Ugandan Medical Schools: Student and Faculty Insights on Integrating a Decolonization-Focused Curriculum
Article scientifique
A shared frailty model for assessing time to seizure remission in adults with epilepsy
Epilepsy remains a significant global health concern with increasing prevalence and incidence. This study aimed to model the time to …
Article scientifique
Why do we need a shift to the transformative paradigm if we are to decolonise global health?
There is growing recognition of the need for global health and associated research to decolonise. Yet discourse so far has …
Article scientifique
Psychosocial interventions for people with comorbid substance use disorders in people with severe mental health conditions in low- and middle-income countries: scoping review
BACKGROUND: The high comorbidity of substance use disorders (SUDs) among people with severe mental health conditions (MHCs) poses major challenges …
Article scientifique
Prophylactic role of artemisinin in modulating FGFR3, HRAS, and TP53 to prevent early-stage urothelial carcinoma in BBN-induced mouse models
PURPOSE: Urinary bladder cancer remains a significant global health challenge, with effective early preventive strategies urgently needed to reduce incidence …
Article scientifique
Routine antenatal ultrasound by nurse-midwives in rural Kenya: a pragmatic trial assessing feasibility and effects of the Mimba Yangu (My Pregnancy) project
Introduction: Task-sharing of obstetric ultrasound between nurse-midwives and doctors has the potential to operationalize the World Health Organization's recommendation of …
Article scientifique
Association between CYP17A1 and HSD3B1 gene polymorphisms and testosterone levels in Nigerian prostate cancer patients
Prostate cancer (PCa) is a primary global health concern and the leading cause of cancer-related deaths in men. Genetic variation …
Article scientifique
Population structure and emergence of resistance to new and repurposed drugs in XDR-TB: insights from a 10-year genomic study in the Western Cape, South Africa review
Background: Extensively drug-resistant tuberculosis (XDR-TB) is a global health threat, being expensive and difficult to treat, with high mortality rates. …