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817 publication(s) trouvée(s)
Article scientifique
A one health perspective on multidrug-resistant bacterial infections: integrated approaches for surveillance, policy and innovation
Multidrug-resistant (MDR) bacterial infections represent a growing global health emergency, driven by interconnected human, animal, and environmental factors. This review …
Article scientifique
Digital Infrastructure for Antimicrobial Susceptibility Testing and Surveillance: A CLSI and EUCAST-Based Model for Resource-Limited Settings (Preprint)
BACKGROUND Antimicrobial resistance (AMR) poses a significant global health threat, requiring effective antimicrobial susceptibility testing (AST) and surveillance systems. At …
Article scientifique
Antibacterial potential of selected extracts and silver nanoparticles from bacterial endophyte harboured by Cola acuminata and Cola nitida (Sterculiaceae) roots
Abstract Introduction Antimicrobial resistance (AMR) is currently a global health issue in most countries. Harnessing endophytic at present. Antibiotic resistance …
Article scientifique
Optimizing syphilis screening in South Africa: efficacy of the iStatis antibody test in point-of-care settings amid reinfection challenges
BACKGROUND: Syphilis poses a significant threat to global health, particularly in high-risk populations and resource-limited settings. Despite progress in HIV …
Article scientifique
Current trends and identified gaps in dysphagia research in Africa: A scoping review
BACKGROUND: In the context of Africa and other resource-limited settings, there is a necessity to address the unique challenges faced …
Article scientifique
How do social norms influence the sexual and reproductive health of very young adolescents in sub-Saharan Africa? A scoping review
Abstract In sub-Saharan Africa (SSA), very young adolescents (VYAs, aged 10–14 years) have the worst sexual and reproductive health (SRH) …
Article scientifique
Chronic kidney disease prevalence and associated risk factors in hypertensive adults at Burao general hospital, Burao City, Somaliland: a cross-sectional study
Background: Chronic kidney disease (CKD) is a significant global health challenge, particularly in low- and middle-income countries where hypertension is …
Article scientifique
The Impact of Lifestyle and Dietary Antioxidants on Diabetes: A Comprehensive Review of Prevention and Management Strategies
Diabetes mellitus is a pervasive global health crisis characterised by chronic hyperglycemia, leading to severe microvascular and macrovascular complications. Oxidative …
Article scientifique
The role of aryl hydrocarbon receptor signalling in COVID-19 pathology and its therapeutic potential
SARS-CoV-2, emerged in Wuhan, China, and rapidly evolved into a global health crisis. Recent evidence highlights the activation of the …
Article scientifique
Determinants of preterm birth among newborns delivered at public referral hospitals in Bahir Dar City, Northwest Ethiopia, 2024
BACKGROUND: Preterm birth, defined as any birth occurring before 37 completed weeks of gestation, remains a significant global health concern …
Article scientifique
Ameliorative effects of Brassica oleracea var. viridis ethanol extract and fractions on cimetidine-induced reproductive toxicity in male Wistar rats
Background Male infertility is a global health issue, with pharmaceutical agents such as cimetidine contributing significantly to gonadotoxicity through antiandrogenic …
Article scientifique
Age-structured malaria model with temperature-dependent dynamics and optimal control analysis within a partial differential equation framework
Malaria remains a significant global health challenge, particularly in sub-Saharan Africa, despite advances in control measures. In 2023, there were …
Article scientifique
Estimated extent of purchasing of antibiotics without a prescription from community pharmacies in a rural province in South Africa and the implications
Background Antimicrobial resistance is a considerable global health threat especially among low- and middle-income countries, exacerbated by considerable inappropriate dispensing …
Article scientifique
Bayesian spatio-temporal modeling and prediction of malaria cases in Tanzania mainland (2016-2023): unveiling associations with climate and intervention factors
Abstract Background Malaria continues to pose a significant global health challenge, affecting approximately 200 million individuals annually and resulting in …
Article scientifique
Varying Malaria Rapid Diagnostic Test Accuracy by Regional Transmission Level and Demographics in Tanzania
Malaria remains a significant global health burden, with approximately 263 million cases across 83 countries. It's essential for malarial infection …
Article scientifique
Defining severe shigellosis in the Enterics for Global Health study: A comparison of leading diarrhea severity definitions among children with Shigella diarrhea
Abstract Background Shigella has high global burden and serious long-term outcomes among young children. Increasing antibiotic resistance makes Shigella vaccine …
Article scientifique
Bacterial Contamination of Inanimate Surfaces and Equipment, Distribution and Susceptibility Patterns in Pediatric Wards at a Northern Tanzania Zonal Referral Hospital
Abstract Background Hospital-acquired infections (HAIs) represent a significant global health concern, contributing to high rates of morbidity and mortality. Globally, …
Article scientifique
Assessing a partnership-based model of surgical education in the Global South: a mixed methods study of the University of Global Health Equity, Rwanda
BACKGROUND: Workforce shortages, resource limitations, and inadequate capacity in African higher education institutions are significant challenges that hinder their global …
Article scientifique
Dyslipidemia as the Predictive Factor for the Severity of Diabetic Retinopathy Among Type 2 Diabetic Patients at KCMC Hospital from 2023 to 2024
Abstract Background Diabetes mellitus (DM) is a global health concern, leading to complications like diabetic retinopathy (DR), a leading cause …
Éditorial
Editorial: Natural remedies repositioned: advancing drug discovery for infectious diseases
Historically, medicinal practices relied on natural remedies as therapeutic agents. Several drugs and drug scaffolds in use today can be …