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Publications
7397 publication(s) trouvée(s)
Article scientifique
Public Health Pharmacology: a framework for population-level immunologic monitoring (PLIM) to optimize vaccine performance in Africa
Despite high administrative immunization coverage across Sub-Saharan Africa, unexpected infectious disease outbreaks pose significant public health challenges. Traditional tracking relies …
Article scientifique
From predictive AI to autonomous food bioprocessing: a critical review of real-time quality monitoring, energy optimization, digital twins, and intelligent process control
Food bioprocessing is transitioning from conventional automation towards intelligent, data-driven, and increasingly autonomous manufacturing. A substantial gap nevertheless remains between …
Article scientifique
Phenotypic and molecular characterization of INPP5K-related congenital muscular dystrophy in four Egyptian patients
Abstract INPP5K -related congenital muscular dystrophy is an ultra-rare autosomal recessive disorder characterized by variable combinations of early-onset cataracts, proximal …
Article scientifique
Different seeds, same pest? Exploring smallholder farmers’ lived experiences of fall armyworm impacts on hybrid and local maize in Kenya
Fall Armyworm (FAW) is a persistent threat to maize-based food systems in sub-Saharan Africa, but less is known about how …
Article scientifique
Production, Purification and Characterization of Thermostable Amylase from Thermophilic Bacteria Isolated from Water and Sediments of Wanzaye Hot Spring, Ethiopia
Article scientifique
Characterisation of 16S rRNA gene, phylogenetic analysis, and multidrug resistance profiling of hospital-associated Myroides and Bacillus strains from Anambra State, Nigeria
Article scientifique
Impact of the Adoption of Digital Technologies on the Technical and Economic Performance of Pineapple Producers in Southern Benin
Article scientifique
Osteogenesis imperfecta and Rheumatoid arthritis: A coincidental association or a genetic overlap? A case report with literature review
Article scientifique
Recombinant thermotolerant alkaline lipase from Lysinibacillus fusiformis for detergent and hard (Ras) cheese applications: cloning, expression, molecular docking, and characterization
BACKGROUND: Thermostable and alkaline lipases are of significant interest for industrial applications, particularly in detergents and food processing. This study …
Article scientifique
Diagnostic and Prognostic Values of Microfibrillar-Associated Protein 5 and Heat Shock Protein 90 Alpha in Patients with HCV-Induced Hepatocellular Carcinoma Undergoing Locoregional Therapy
OBJECTIVES: This study aimed to assess the role of HSP90 alpha and MFAP5 as potential diagnostic and prognostic markers for …
Article scientifique
A Multi-Model Comparison of Supervised Machine Learning for Predicting Antimicrobial Resistance in ESKAPE Pathogens
Antimicrobial resistance (AMR) causes about 1.3 million deaths annually, yet culture-based susceptibility testing delays treatment by 24–72 hours. Whole genome …
Article scientifique
Pharmacological characterization and nephroprotective potential of venoms from three egyptian scorpion species
Introduction: Scorpion venoms are complex natural mixtures rich in bioactive molecules with emerging pharmacological relevance. Drug-induced kidney injury, particularly from …
Article scientifique
Mapping the Prevalence of BRCA1 and BRCA2 Mutations in Hereditary Breast and Ovarian Cancer Across Africa: A Systematic Review and Meta-Analysis
BACKGROUND: BRCA1 and BRCA2 gene mutations are major contributors to hereditary breast and ovarian cancer syndrome (HBOC). While mutation prevalence …
Article scientifique
Host Ontogeny Structures Gut Microbiome Composition and Pathogen-Associated Bacterial Communities in the Endangered Ethiopian Wolf (Canis simensis)
Article scientifique
Influence of Exosomes on Tumorigenic Behavior in Triple-Negative Breast Cancer Cells through STAT3 Inhibition in Autophagy
OBJECTIVES: The prime aim of this research was to evaluate the effect of exosomes on the tumorigenic behavior of TNBC …
Article scientifique
Metabolomic and biochemometric profiling of Tecoma stans with mechanistic insights of its in vitro cytotoxic activity
Tecoma stans is an ornamental plant recognized for its diverse biological activities, including notable cytotoxic effects. This study integrates LC-MS/MS-guided …
Article scientifique
Prevalence, and Antimicrobial Resistance Profile of Escherichia coli O157:H7 Isolated from Human, Animal, and Environmental Samples in Ethiopia: A Systematic Review and Meta-Analysis
Article scientifique
Prognostication of Breast Cancer Patients Using the Nottingham Prognostic Index in Kenyatta National Hospital
Article scientifique
Impact of combined acidic and oxidative stress on guanine DNA damage
Abstract This research investigates guanine reactivity through quantum-chemical methods which study its behaviour during simultaneous oxidative and acidic stress using …
Article scientifique
LC-MS/MS-based phytochemical profiling of Erythrina caffra leaves, isolation of a novel sterol glycoside, and evaluation of antioxidant, cytotoxic, and anti-sars-cov-2 activities
From the crude ethanol extract of Erythrina caffra leaves, a new compound, stigmasta-5,22-diene 3-O-(6’-tridecanoate)-β-D-glucopyranoside (1), along with stigmasta-5,22-diene (2), lutein …
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