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Publications
7367 publication(s) trouvée(s)
Article scientifique
Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of Tuberculosis
Despite a slight decline since 2014, tuberculosis (TB) remains the major most deadly infectious disease worldwide with about 1.5 million …
Article scientifique
Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry
To characterize the extent and impact of ancestry-related biases in precision genomic medicine, we use 642 whole-genome sequences from the …
Article scientifique
Antimicrobial susceptibility testing in predicting the presence of carbapenemase genes in Enterobacteriaceae in South Africa
Carbapenem-resistant Enterobacteriaceae (CRE) is a concern in South Africa and worldwide. It is therefore important that these organisms be accurately …
Article scientifique
A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
The African Diaspora in the Western Hemisphere represents one of the largest forced migrations in history and had a profound …
Article scientifique
First Report of Outbreaks of the Fall Armyworm Spodoptera frugiperda (J E Smith) (Lepidoptera, Noctuidae), a New Alien Invasive Pest in West and Central Africa
The fall armyworm Spodoptera frugiperda is a prime noctuid pest of maize on the American continents where it has remained …
Article scientifique
Draft genome sequence of Thermoactinomyces sp. strain AS95 isolated from a Sebkha in Thamelaht, Algeria
The members of the genus Thermoactinomyces are known for their protein degradative capacities. Thermoactinomyces sp. strain AS95 is a Gram-positive …
Article scientifique
Genetic Diversity and Phenotypic Variation in an Introgression Line Population Derived from an Interspecific Cross between Oryza glaberrima and Oryza sativa
The introduction of closely related species genomic fragments is an effective way to enrich genetic diversity and creates new germplasms …
Article scientifique
Overexpression of synuclein-γ predicts lack of benefit from radiotherapy for breast cancer patients
BACKGROUND: Although radiotherapy following mastectomy was demonstrated to reduce the recurring risk and improve the prognosis of patients with breast …
Article scientifique
Identification of β Clamp-DNA Interaction Regions That Impair the Ability of E. coli to Tolerate Specific Classes of DNA Damage
The E. coli dnaN-encoded β sliding clamp protein plays a pivotal role in managing the actions on DNA of the …
Article scientifique
RNAseq analysis of heart tissue from mice treated with atenolol and isoproterenol reveals a reciprocal transcriptional response
BACKGROUND: The transcriptional response to many widely used drugs and its modulation by genetic variability is poorly understood. Here we …
Article scientifique
Occurence of ArmA and RmtB Aminoglycoside Resistance 16S rRNA Methylases in Extended-Spectrum β-Lactamases Producing Escherichia coli in Algerian Hospitals
The aim of this study, was to characterize the extended-spectrum-β-lactamases (ESBLs) producing clinical strains of Escherichia coli isolated between January …
Article scientifique
Multiparametric Magnetic Resonance Investigation of Brain Adaptations to 6 Days at 4350 m
OBJECTIVE: Hypoxic exposure in healthy subjects can induce acute mountain sickness including headache, lethargy, cerebral dysfunction, and substantial cerebral structural …
Article scientifique
Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola
Abstract The selectivity filter is an essential functional element of K+ channels that is highly conserved both in terms of …
Article scientifique
Anti-tumor effect of polysaccharides from rhizome of Curculigo orchioides Gaertn on cervical cancer
Purpose: To investigate the anti-tumor effects of polysaccharides from Curculigo orchioides (PDC) on cervical cancer and the possible mechanisms involved.Methods: …
Article scientifique
From Human Geography to Biological Invasions: The Black Rat Distribution in the Changing Southeastern of Senegal
In the contemporary context of zoonosis emergence and spread, invasive species are a major issue since they represent potential pathogen …
Article scientifique
Genome-wide In Silico Analysis, Characterization and Identification of Microsatellites in Spodoptera littoralis Multiple nucleopolyhedrovirus (SpliMNPV)
In this study, we undertook a survey to analyze the distribution and frequency of microsatellites or Simple Sequence Repeats (SSRs) …
Article scientifique
Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study
Sorafenib is the only chemotherapeutic agent currently approved for unresectable hepatocellular carcinoma (HCC). However, poor response rates have been widely …
Article scientifique
Lebetin 2, a Snake Venom-Derived Natriuretic Peptide, Attenuates Acute Myocardial Ischemic Injury through the Modulation of Mitochondrial Permeability Transition Pore at the Time of Reperfusion
Cardiac ischemia is one of the leading causes of death worldwide. It is now well established that natriuretic peptides can …
Article scientifique
Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti
The NF-κB pathway has critical roles in cancer, immunity and inflammatory responses. Understanding the mechanism(s) by which mutations in genes …
Article scientifique
Low genetic diversity and recent demographic expansion in the red starfish Echinaster sepositus (Retzius 1816)
Understanding the phylogeography and genetic structure of populations and the processes responsible of patterns therein is crucial for evaluating the …