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Publications
7389 publication(s) trouvée(s)
Article scientifique
Tying malaria and microRNAs: from the biology to future diagnostic perspectives
Symptoms caused by bacterial, viral and malarial infections usually overlap and aetiologic diagnosis is difficult. Patient management in low-resource countries …
Article scientifique
An assessment of rehabilitation success in an African grassland using ants as bioindicators
Many studies that evaluate rehabilitation make use of invertebrate bioindicators. Invertebrates, especially ants, make useful indicators as they are sensitive …
Article scientifique
A Quantitative Approach to Analyzing Genome Reductive Evolution Using Protein–Protein Interaction Networks: A Case Study of Mycobacterium leprae
The advance in high-throughput sequencing technologies has yielded complete genome sequences of several organisms, including complete bacterial genomes. The growing …
Article scientifique
Feline panleukopaenia virus in captive non-domestic felids in South Africa
An outbreak of feline panleukopaenia virus (FPLV) infection was diagnosed by pathology, electron microscopy and polymerase chain reaction (PCR) in …
Article scientifique
Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli
S-adenosylmethionine decarboxylase (PfAdoMetDC) from Plasmodium falciparum is a prospective antimalarial drug target. The production of recombinant PfAdoMetDC for biochemical validation …
Article scientifique
Phylogenetic evidence for intratypic recombinant events in a novel human adenovirus C that causes severe acute respiratory infection in children
Human adenoviruses (HAdVs) are prevalent in hospitalized children with severe acute respiratory infection (SARI). Here, we report a unique recombinant …
Article scientifique
Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African ixodid tick species
BACKGROUND: The tick population of Africa includes several important genera belonging to the family Ixodidae. Many of these ticks are …
Article scientifique
COLORFUL-Circuit: A Platform for Rapid Multigene Assembly, Delivery, and Expression in Plants
Advancing basic and applied plant research requires the continuous innovative development of the available technology toolbox. Essential components of this …
Article scientifique
The T-box transcription factor TBX3 drives proliferation by direct repression of the p21WAF1 cyclin-dependent kinase inhibitor
BACKGROUND: TBX3, a member of the T-box family of transcription factors, is essential in development and has emerged as an …
Article scientifique
Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
It is well recognized that the immune system and metabolism are highly integrated. In this context, multilevel interactions between metabolic …
Article scientifique
Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration
BACKGROUND: Breast cancer incidence and mortality vary significantly among different nations and racial groups. African nations have the highest breast …
Article scientifique
De Novo Occurrence of a Variant in ARL3 and Apparent Autosomal Dominant Transmission of Retinitis Pigmentosa
BACKGROUND: Retinitis pigmentosa is a phenotype with diverse genetic causes. Due to this genetic heterogeneity, genome-wide identification and analysis of …
Article scientifique
Development of Microsatellite Markers and Analysis of Genetic Diversity and Population Structure of Colletotrichum gloeosporioides from Ethiopia
Twenty three polymorphic microsatellite markers were developed for citrus plant pathogenic fungus, Colletotrichum gloeosporioides, and were used to analyze genetic …
Article scientifique
Additive opportunistic capture explains group hunting benefits in African wild dogs
African wild dogs (Lycaon pictus) are described as highly collaborative endurance pursuit hunters based on observations derived primarily from the …
Article scientifique
Towards Improving Point-of-Care Diagnosis of Non-malaria Febrile Illness: A Metabolomics Approach
INTRODUCTION: Non-malaria febrile illnesses such as bacterial bloodstream infections (BSI) are a leading cause of disease and mortality in the …
Article scientifique
MicroRNA from Moringa oleifera: Identification by High Throughput Sequencing and Their Potential Contribution to Plant Medicinal Value
Moringa oleifera is a widespread plant with substantial nutritional and medicinal value. We postulated that microRNAs (miRNAs), which are endogenous, …
Article scientifique
Parent-of-origin effects on genome-wide DNA methylation in the Cape honey bee (Apis mellifera capensis) may be confounded by allele-specific methylation
BACKGROUND: Intersexual genomic conflict sometimes leads to unequal expression of paternal and maternal alleles in offspring, resulting in parent-of-origin effects. …
Article scientifique
Cost-Effectiveness of Antivenoms for Snakebite Envenoming in 16 Countries in West Africa
BACKGROUND: Snakebite poisoning is a significant medical problem in agricultural societies in Sub Saharan Africa. Antivenom (AV) is the standard …
Article scientifique
miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma
Bromodomain containing 7 (BRD7) was identified as a nuclear transcriptional regulatory factor. BRD7 functions as a tumor suppressor in multiple …
Article scientifique
Naringin Reduces Hyperglycemia-Induced Cardiac Fibrosis by Relieving Oxidative Stress
INTRODUCTION: Hyperglycemia promotes myocardial fibrotic lesions through upregulation of PKC and p38 in response to redox changes. The effects of …