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7366 publication(s) trouvée(s)
Article scientifique
HOXA9 and CD163 potentiate pancreatic ductal adenocarcinoma progression
BACKGROUND: The role of HOXA9 requires investigations in pancreatic ductal adenocarcinoma (PDAC) as HOXA9 inhibitors are being developed. HOXA9 might …
Article scientifique
Compounding impacts of COVID-19, cyclone and price crash on vanilla farmers’ food security and natural resource use
The intersection of the COVID-19 pandemic with other crises can amplify vulnerabilities and push communities further into poverty. In low-income …
Article scientifique
LncRNA LYPLAL1, miR-204-5p, and SIRT1: novel signatures for risk assessment of diabetic macrovascular complications
Long-term, uncontrolled diabetes mellitus can lead to micro- and macrovascular problems. The protective function of lncRNA LYPLAL1 is to reduce …
Article scientifique
Enhancing the biotransformation of progesterone to the anticancer compound testololactone by Penicillium chrysogenum Ras3009: kinetic modelling and efficiency maximization
Abstract Background Biotransformation of steroid compounds into therapeutic products using microorganisms offers an eco-friendly and economically sustainable approach to the …
Article scientifique
Fusarium verticillioides pigment: production, response surface optimization, gamma irradiation and encapsulation studies
BACKGROUND: Natural pigments are becoming more significant because of the rising cost of raw materials, pollution, and the complexity of …
Article scientifique
Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with bacterial diarrhea susceptibility in Barki lambs
BACKGROUND: Despite the fact that diarrhea is more accurately described as a clinical symptom than a disease. Diarrhea is one …
Article scientifique
Non-metabolic enzyme function of pyruvate kinase M2 in breast cancer
Breast cancer (BC) is a prevalent malignant tumor in women, and its incidence has been steadily increasing in recent years. …
Article scientifique
A combination of joint linkage and genome-wide association study reveals putative candidate genes associated with resistance to northern corn leaf blight in tropical maize
Northern corn leaf blight (NCLB), caused by Setosphaeria turcica, is a major fungal disease affecting maize production in sub-Saharan Africa. …
Article scientifique
An investigative study on Yersinia enterocolitica in animals, humans and dried milk in New Valley Governorate, Egypt
BACKGROUND: Yersiniosis is one of the most significant intestinal disorders caused by Yersinia enterocolitica and affects both humans and animals. …
Article scientifique
Predictive immunoinformatics reveal promising safety and anti-onchocerciasis protective immune response profiles to vaccine candidates (Ov-RAL-2 and Ov-103) in anticipation of phase I clinical trials
Onchocerciasis (river blindness) is a debilitating tropical disease that causes significant eye and skin damage, afflicting millions worldwide. As global …
Article scientifique
Three-dimensional assessment of the skeletal characteristics accompanying unilateral maxillary canine impaction: a retrospective cone-beam computed tomography study
BACKGROUND: Environmental and genetic factors associated with canine impaction have been extensively researched, whereas the bone characteristics in the impaction …
Article scientifique
Evaluation of anti-biofilm and anti-virulence effect of zinc sulfate on Staphylococcus aureus isolates
Staphylococcus aureus produces a plethora of virulence factors to invade and establish infections in the host system, and biofilms are …
Article scientifique
Suppression of virulence factors of uropathogenic Escherichia coli by Trans-resveratrol and design of nanoemulgel
BACKGROUND: Development of multidrug resistance in Uropathogenic Escherichia coli (UPEC) makes treatment of Urinary Tract Infections (UTIs) a major challenge. …
Article scientifique
Pathotype determination of sorghum anthracnose (Colletotrichum sublineola) isolates from Ethiopia using sorghum differentials
Introduction Sorghum anthracnose, caused by Colletotrichum sublineola , is the most destructive disease of sorghum, which causes up to 80% …
Article scientifique
Uncovering the therapeutic potential of green pea waste in breast cancer: a multi-target approach utilizing LC-MS/MS metabolomics, molecular networking, and network pharmacology
Abstract Background Pisum sativum (PS) is a universal legume plant utilized for both human and animal consumption, particularly its seeds, …
Article scientifique
Analysis of current and future bioclimatic suitability for C. arabica production in Ethiopia
The coffee sector in Ethiopia is the livelihood of more than 20% of the population and accounts more than 25% …
Article scientifique
Predominance of enterotoxigenic Escherichia coli among ESBL/plasmid-mediated AmpC-producing strains isolated from diarrheic foals: a public health concern
BACKGROUND: The upsurge of diarrheagenic E. coli pathotypes carrying extended-spectrum beta-lactamases (ESBLs)/plasmid-mediated AmpC β-lactamase (pAmpC) among animals constitutes an emerging …
Article scientifique
Genomic dynamics of high-risk carbapenem-resistant Klebsiella pneumoniae clones carrying hypervirulence determinants in Egyptian clinical settings
BACKGROUND: Ongoing studies have revealed the global prevalence of severe infections caused by the hypervirulent strains of Klebsiella pneumoniae (K. …
Article scientifique
Resistance patterns, virulence determinants, and biofilm genes of multidrug-resistant Pseudomonas aeruginosa isolated from fish and fish handlers
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic bacterium that is widely distributed in aquatic environments and causes major economic losses …
Article scientifique
Antibacterial and wound healing potential of biosynthesized zinc oxide nanoparticles against carbapenem-resistant Acinetobacter baumannii: an in vitro and in vivo study
Abstract Carbapenem-resistant Acinetobacter baumannii denotes a significant menace to public health, and it mandates an urgent development of new effective …