7380
Publications
38641
Auteurs uniques
0
Pays représentés
Sous-domaines
Biologie synthétique
0 publication(s)
Biotechnologies agricoles
0 publication(s)
Biotechnologies environnementales
0 publication(s)
Biotechnologies industrielles
0 publication(s)
Biotechnologies médicales
0 publication(s)
Publications
7380 publication(s) trouvée(s)
Article scientifique
Structure-guided optimization of N-sulfonylpiperidines toward potent multi-target anticancer agents
Cancer poses a significant therapeutic challenge due to its multifactorial origin and resistance to conventional remedies. Our previous efforts identified …
Article scientifique
GCKR genetic variants and circulating FGF21 identify a metabolic risk signature in metabolic dysfunction-associated steatotic liver disease
BACKGROUND & AIMS: Interindividual variability in metabolic dysfunction–associated steatotic liver disease (MASLD) onset and its progressive inflammatory stage, metabolic dysfunction–associated …
Article scientifique
Modulation of oxidative stress and P53/PCNA signaling by glucosodiene-loaded nanoferrites (GLONF) in ehrlich solid tumor–induced hepatotoxicity
Ehrlich solid tumors are commonly used as a model to study tumor growth and evaluate potential anticancer therapies. Current study …
Article scientifique
Yttrium oxide nanoparticles induce potent selective cytotoxicity in HeLa cervical cance cells through ROS-mediated genomic instability and mitochondrial apoptosis
Cervical cancer remains a leading cause of cancer-related mortality, emphasizing the need for safer, more selective therapies. Yttrium oxide nanoparticles …
Article scientifique
Snake repellent safety and efficacy in Sub-Saharan Africa. What is the evidence?
Sales of snake repellents are booming in Sub-Saharan Africa (SSA). A recently published study of commercial snake repellents available across …
Article scientifique
Limits of rapid diagnostics: genomic and structural insights into OXA-48–like mediated carbapenem resistance in Escherichia coli
Carbapenem-resistant Escherichia coli (CREC) represent a major clinical threat because of limited treatment options and frequent multidrug resistance. While rapid …
Article scientifique
Combined antioxidant therapy with quercetin and curcumin protects against radiation-induced nephrotoxicity
This study aimed to explore the protective effects of quercetin and curcumin against kidney damage caused by gamma radiation in …
Article scientifique
Anticarcinogenic effects of miR-199a-loaded gold nanoparticles on hepatocellular carcinoma: in vitro study
Hepatocellular carcinoma (HCC) represents a critical oncological challenge demanding innovative therapeutic interventions. miRNA has been known to play an important …
Article scientifique
Biochemical and molecular responses of Spodoptera frugiperda to insecticide exposure: detoxification enzymes, gene expression, and genotoxic effects
Spodoptera frugiperda (fall armyworm) is a highly destructive agricultural pest with a remarkable ability to develop resistance to insecticides, posing …
Article scientifique
Prime editing: a new frontier in precision genome engineering for rice improvement
Rice ( Oryza sativa ) is a primary cereal crop that provides food for more than half of the global …
Article scientifique
Whole-genome sequencing-based characterization of resistome and virulome in Klebsiella pneumoniae isolated from ready-to-eat foods
Klebsiella ( K. ) pneumoniae is a major antimicrobial-resistant pathogen of global concern. It has increasingly been reported outside clinical …
Article scientifique
Bioactive compounds as therapeutic modulators of metabolic syndrome: targeting inflammation and gut microbiota regulation
Food bioactives, including polyphenols, flavonoids, omega-3 fatty acids, and glucosinolates, play a crucial role in preventing metabolic syndrome by modulating …
Article scientifique
The role of the microbiome in gynecological cancers: implications for diagnosis and treatment
Gynecological malignancies such as cancer of the cervix, ovary, endometrium, vulva, and vagina pose a severe global health burden. Although …
Article scientifique
Climatic and socio-environmental drivers of Cholera epidemics: Cascading effects and spatial variability in developing regions
Cholera remains a persistent public health challenge in developing countries, driven by poor Water, Sanitation and Hygiene (WASH) infrastructure and …
Article scientifique
Silent spreaders: optimal control of asymptomatic cholera transmission through adaptive stochastic modeling
Cholera transmission dynamics are complicated by asymptomatic carriers and environmental stochasticity often overlooked in standard models. We develop a novel …
Article scientifique
Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review
Introduction: Messenger RNA (mRNA) therapeutics have advanced from experimental platforms to clinical application, driven largely by the success of lipid …
Article scientifique
Variable progressive behavior of Klebsiella pneumoniae at different sites of infection
Klebsiella pneumoniae has persisted for decades as a major global health threat. Although vaccination is widely recognized as the most …
Article scientifique
Building Bridges of Understanding: Enhancing Communication Strategy on Genome Editing in Nigeria
Genome editing (GEd) has been mired in confusion and low public understanding. The inadequacy of information and the society's comprehension …
Article scientifique
Cholera in Kenya: A scoping review of current research, evidence gaps and future directions
Cholera remains a major public health challenge in Kenya, driven by environmental pollution, poor water, sanitation, and hygiene (WASH) facilities, …
Article scientifique
Chloroplast genome assembly, annotation, comparative genomics, and genetic diversity analysis of a vulnerable endemic species Lavandula maroccana Murb
Lavandula maroccana Murb., an endemic species of the western Mediterranean, is classified as vulnerable and was added to the International …