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Publications
7378 publication(s) trouvée(s)
Article scientifique
Clinical and molecular characteristics of fructose 1, 6 bisphosphatase deficiency in 6 Egyptian patients and two common variants
BACKGROUND: Fructose 1, 6 bisphosphatase (FBPase) deficiency is a rare autosomal recessive disease caused by mutations in the FBP1 gene. …
Article scientifique
Diagnostic and therapeutic potential of microRNAs and long noncoding RNAs in the molecular mechanisms of Alzheimer disease
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by complex molecular mechanism, including amyloid-beta (Aβ) plaque accumulation, Tau …
Article scientifique
Low occurrence and clonal relatedness of multi-drug resistant Escherichia coli carrying transmissible colistin resistance mcr-1 genes in Ugandan poultry
Introduction Colistin resistance is an emerging global health concern that can lead to limited treatment options for life-threatening human infections. …
Article scientifique
Recyclable and eco-friendly xanthan gum-based hygroscopic hydrogel for atmospheric water harvesting
Water scarcity is a pressing issue in several regions of the world. Nevertheless, atmospheric water vapor offers an abundant freshwater …
Article scientifique
Antibacterial and antiviral potential of harmalacidine hydrochloride, a β-carboline alkaloid, against respiratory tract pathogens: Staphylococcus aureus and H1N1 influenza virus
Respiratory infections remain a leading cause of morbidity and mortality, necessitating new therapeutic strategies. This study evaluated the antiviral and …
Article scientifique
Plasma lipopolysaccharide levels predict mortality in acutely ill children in Low- and Middle-Income Countries
Childhood mortality remains high in low-resource settings, where environmental enteric dysfunction (EED) is prevalent. Peripheral blood bacterial lipopolysaccharides (LPS) are …
Article scientifique
Nationwide variation of snakebite incidence in Kenya: Community surveys as an integrated NTD approach
INTRODUCTION: Snakebite envenoming is a neglected tropical disease (NTD) of public health concern in Kenya. Its true burden remains elusive …
Article scientifique
Health professionals’ knowledge, attitudes, and practices in snakebite management: A study from high-burden areas in the Afar Region, Ethiopia
BACKGROUND: Snakebite envenoming remains a significant public health challenge, particularly in rural and resource-limited tropical regions such as sub-Saharan Africa. …
Article scientifique
Phenolic profile of different solvent extracts of Reseda alba L. and evaluation of anti-quorum sensing, antioxidant, and enzyme inhibition activities
Background Reseda alba (white mignonette) is a wild, edible, and medicinal plant native to the Mediterranean region, with limited studies …
Article scientifique
Diagnostic and therapeutic potential of exosomal circRNAs in cancer: decoding the circular code toward precision medicine
Circular RNAs (circRNAs), a unique class of non-coding RNAs, have gained attention due to their stable closed-loop structure and involvement …
Article scientifique
From pandemics to preparedness: harnessing AI, CRISPR, and synthetic biology to counter biosecurity threats
Biosecurity threats, which include natural outbreaks, laboratory accidents, and intentional bioterrorism, are a major issue for global health security. The …
Article scientifique
Bioinformatics analysis to explore the potential prognostic utility of hsa-miR-103a-3p in head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC), the seventh most common cancer globally, has not yet seen an exploration of …
Article scientifique
RareLink: scalable REDCap-based framework for rare disease interoperability linking international registries to FHIR and Phenopackets
While Research Electronic Data Capture (REDCap) is widely adopted in rare disease research, its unconstrained data format often lacks native …
Article scientifique
Comparison of Peganum harmala L. leaves extract nanoformulations against herpes simplex virus type 1 guided by network pharmacology analysis
Abstract Herpes simplex virus type 1 (HSV-1) is a highly prevalent viral infection with limited medications. Thus, search for safe …
Article scientifique
The implication of aberrant NRF2 activation in management of female cancers
The overactivation of NRF2 (Nuclear factor erythroid 2-related factor 2) in female malignancies is an emerging field of study with …
Article scientifique
Gut microbiome dysbiosis in hepatocellular carcinoma patients with persistent HCV viremia versus viral clearance: a cross-sectional study
BACKGROUND: Hepatocellular carcinoma (HCC) remains a lethal complication of chronic hepatitis C virus (HCV) infection, even after successful direct-acting antiviral …
Article scientifique
Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation
Prenylflavonoids are widespread in plants, which are considered valuable sources of natural polyphenolic compounds with isoprenyl groups, including flavones, flavanones, …
Article scientifique
Comparison of metabolic profiles, regulatory pathways, and quorum sensing inhibition activity of brown mustard seeds (Brassica juncea L.) post germination and roasting treatments
While mustard seeds offer an enormous wealth of biologically valuable compounds, the obtainable data unveiling the effect of germination and …
Article scientifique
Diphtheria outbreak in Somalia: a weekly sitrep on the recent health crisis-2025
The global diphtheria incidence has fallen following widespread use of the diphtheria-tetanus-pertussis (DTP) vaccine; pockets of low coverage and disrupted …
Article scientifique
A review on extraction, isolation, characterization of bioactive compounds obtained from agri-food waste and their potential for industrial application
The increased global food demand has resulted into extensive agricultural activities to offset the demand. The agri-activities generates large volumes …