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7375 publication(s) trouvée(s)
Article scientifique
Acute and sub-acute toxicity assessment of methanolic stem bark extract of Khaya anthotheca (Meliaceae) in Wistar rats
Abstract Background Khaya anthotheca (Meliaceae) is a medicinal plant with a wide range of therapeutic properties attributable mainly to the …
Article scientifique
An efficient machine-learning framework for predicting protein post-translational modification sites
Post-Translational Modifications (PTMs), particularly lysine 2-hydroxyisobutyrylation (Khib), represent critical regulatory mechanisms governing protein structure and function, with mounting evidence underscoring …
Article scientifique
Genomic epidemiology of enteropathogenic Escherichia coli in southwestern Nigeria
BACKGROUND: Enteropathogenic Escherichia coli (EPEC) are etiological agents of diarrhea. We studied the genetic diversity and virulence factors of EPEC …
Article scientifique
Modulatory role of Spirulina platensis in oxidative stress, apoptosis, and gene expression in a rat model of dexamethasone-induced hepatotoxicity
The rising prevalence of hyperlipidemia and hepatic disorders has intensified interest in the therapeutic use of functional foods and botanical …
Article scientifique
PEGylated liposomal metformin overcomes pharmacokinetic barriers to trigger potent mitochondrial disruption and cell cycle arrest in hepatocellular carcinoma
This study presents a comprehensive experimental and computational evaluation of PEGylated liposomal metformin as a nanocarrier-based therapeutic strategy for hepatocellular …
Article scientifique
Influence of the magnetic field on the characteristics of sandy soil, groundwater, fruit quality, and peach water productivity at different irrigation distances in a desert environment
Abstract Enhancing Florida Prince peach cultivars' quality, yield, and fruiting in the face of water scarcity was the aim of …
Article scientifique
Epidemiology of paediatric snakebites in Northeastern Nigeria: a retrospective single-center study
BACKGROUND: Nigeria remains one of the highest burden bearers of snakebite envenoming in sub-Saharan Africa. In Northeastern Nigeria, where agricultural …
Article scientifique
Comprehensive evaluation of Lagenaria siceraria and Cucurbita species seeds: proximate composition, antioxidant potential, lipid profiling, and oil properties
A b s t r a c t. Seeds from the Cucurbitaceae family are generally considered waste.This study focuses on …
Article scientifique
Assessment of the antifungal activity of Actinidia deliciosa derived exosome like nanoparticles
The Exosome-like nanoparticles (ELNs) are essential for both intra- and inter-kingdom communication. The presence and function of plant ELNs discharged …
Article scientifique
Insights into the tripartite relationship between cervical cancer, human papillomavirus, and the vaginal microbiome: a mega-analysis
BACKGROUND: Cervical cancer (CC) is the fourth most prevalent malignancy among women worldwide, where 99.7% of the cases are linked …
Article scientifique
Impact of Micro-RNAs as biomarkers for end-stage renal disease related to hypertension and diabetes
End-stage renal disease (ESRD) is a rapidly increasing global health and healthcare challenge. MicroRNAs (miRNAs) have been implicated in kidney …
Article scientifique
The genomic configurations driving antimicrobial resistance and virulence in colistin resistant Pseudomonas aeruginosa from an Egyptian Tertiary Oncology Hospital
Pseudomonas aeruginosa, recognized by the World Health Organization as a critical priority pathogen, exhibits significant genomic plasticity and a high …
Article scientifique
Long intergenic non-coding RNA 00511 (LINC00511) genetic variations and haplotype implication for colorectal cancer susceptibility and prognosis
Abstract Long intergenic non-coding RNA 00,511 (LINC00511) is considered an oncogene for various cancers. However, the association between LINC00511 single …
Article scientifique
Unravelling Artemisia species genetic variation via DNA barcoding, ISSR and RAPD with the development of eco-specific SCAR markers
BACKGROUND: Genus Artemisia is one of the largest and most globally spread genera, comprising more than 500 species known for …
Article scientifique
Phenotypic plasticity in trait performance of common dairy goat breeds under diverse environments: a systematic review
Introduction Dairy goat genotypes thrive across a range of ecological systems, making phenotypic plasticity highly relevant under constant environmental fluctuations. …
Article scientifique
Multidrug-resistant E. Coli in wastewater sources: a comparative study and identification of resistance hotspots
Abstract Background This work aims to study the patterns of resistance to antibiotics in wastewater samples collected from hospitals, the …
Article scientifique
In-cell NMR reveals the first direct observation of endogenous interaction between HIV Tat protein and Tat RNA aptamer in human cells
RNA-protein interactions lie at the basis of numerous regulatory and functional cellular biological processes, including transcriptional control, RNA processing, nuclear …
Article scientifique
Novel dual gland GAN architecture improves human protein localization classification using salivary and pituitary gland inspired loss functions
Cellular classification is essential for understanding biological processes and disease mechanisms. This paper introduces a novel approach that employs two …
Article scientifique
Combined Hyaluronic Acid Nanobioconjugates Impair CD44-Signaling for Effective Treatment Against Obesity: A Review of Comparison with Other Actors
CD44, a key hyaluronic acid (HA) receptor, has emerged as a central mediator of adipose tissue inflammation, remodeling, and insulin …
Article scientifique
Mastering the art of sectioning: a comprehensive guide to slide-microtome technology and histological applications
The well-known technique of microtomy, which is an essential cutting tool, was first developed for light and transmission electron microscope …