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7371 publication(s) trouvée(s)
Article scientifique
Long non-coding RNAs PCAT-1 and FENDRR: diagnostic and prognostic potential in papillary thyroid carcinoma
BACKGROUND: Thyroid cancer is the most prevalent endocrine cancer worldwide. Certain histological subtypes of papillary thyroid carcinoma (PTC) exhibit aggressive …
Article scientifique
ADAT3-related neurodevelopmental disorder in 24 new patients with a high frequency of the p.Val144Met and a new founder variant
Biallelic variants in the adenosine deaminase tRNA specific 3 (ADAT3) gene are associated with a distinct neurodevelopmental disorder characterized by …
Article scientifique
Behavioral and physiological insights into cross-stage interactions in the desert locust
Gregarious desert locusts produce stage-specific pheromones that facilitate cohesive behavior in juveniles and synchronize maturation and mating in sexually mature …
Article scientifique
Characterization and virulence of yeasts associated with neonatal thrush
BACKGROUND: Species of Candida are the main cause of aggressive fungal infections in preterm newborns. These infections are linked to …
Article scientifique
Analysis and simulation of a novel stochastic RNA silencing model
The current work aims to investigate how random environmental fluctuations affect the dynamics of the RNA Silencing model. To capture …
Article scientifique
Genetic diversity and population structure of the indigenous goat population in Tunisia's northwest
Elucidating genetic diversity is critical for improving breeding strategies. To this end, the present study investigated the genetic diversity and …
Article scientifique
A Novel Adaptive Sparse Deep Feature Selection Method for Enhanced Gene-based Cancer Classification
The Adaptive Sparse Deep Feature Selection (ASDFS) method introduces a novel deep learning-based approach to enhance gene-based cancer classification. Designed …
Article scientifique
Novel insights into SNORD-78 and miR-122-5P the predicted diagnostic indexes of lung cancer: drug-loaded liposome formulations competing methylcholanthrene-induced lung cancer
Abstract Micro-RNAs (mi-RNAs) can regulate various tumor suppressor genes or oncogenes thus they were monitored in various types of cell …
Article scientifique
The landscape of pediatric genetic white matter disorders at a tertiary referral hospital in Upper Egypt and the report of 31 novel variants
BACKGROUND: Leukodystrophies (LDs) and genetic leukoencephalopathies (GLEs) encompass the spectrum of genetic white matter disorders (GWMDs). Despite their clinical significance, …
Article scientifique
NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans
Introduction Genetic variation in genes coding for enzymes metabolising antihypertensive drugs, may affect the efficacy of angiotensin converting enzyme (ACE) …
Article scientifique
Navigating the cholera elimination roadmap in Zambia – A scoping review (2013–2024)
BACKGROUND: Cholera outbreaks are increasing in frequency and severity, particularly in Sub-Saharan Africa. Zambia, committed to ending cholera by 2025, …
Article scientifique
Production and optimization of polyglutamic acid from Bacillus licheniformis: effect of low levels of gamma radiation
Polyglutamic acid (PGA), has several beneficial characteristics and advantageous uses. The microbial biopolymer is released from a variety of organisms, …
Article scientifique
Ecological and environmental conditions correlate with flea population within human habitations in a plague focus, Mbulu district, Tanzania
Plague persistence remains a major health concern in some African countries. Although the role of some flea vectors in their …
Article scientifique
Antimicrobial resistance and molecular detection of extended-spectrum ß-lactamase (ESBL)-producing Escherichia coli in municipal wastewater in Marrakech
Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) poses a major threat to public health. However, its environmental dissemination, especially through wastewater, remains …
Article scientifique
Extended-spectrum β-lactamase-producing Enterobacterales among people living with human immunodeficiency virus across the globe: A systematic review and meta-analysis
BACKGROUND: People living with HIV are vulnerable to antibiotic-resistant bacterial infections because of frequent healthcare visits, the consumption of many …
Article scientifique
Biofilm and surface-motility profiles under polymyxin B stress in multidrug-resistant KAPE pathogens isolated from Ghanaian hospital ICUs
species) from the hospital environment. As opportunistic pathogens, KAPE leverage the formation of biofilms and swarms to survive stringent environmental …
Article scientifique
Gut microbiota composition differences are associated with geographic location and age in malaria-endemic regions of Rwanda
Evidence suggests that a significant interplay exists between the host gut microbiota and both the transmission and severity of malaria. …
Article scientifique
Studying the electronic properties of SiO2/GO/Pb3O4/Bi2O3 composite structure
Abstract This study investigates the electronic properties of a proposed composite structure consisting of SiO2, Pb3O4, Bi2O3, and graphene oxide …
Article scientifique
The role of pioneering transcription factors, chromatin accessibility and epigenetic reprogramming in oncogenic viruses
Oncogenic viruses typically manipulate host cellular mechanisms to drive tumorigenesis. They exploit pioneering transcription factors to modify gene expression, enabling …
Article scientifique
Unmasking and tackling the underestimation of the cholera burden in Africa: A viewpoint
Cholera remains a significant public health challenge in Africa, with the continent recording the highest Case Fatality Ratio of 1.9% …