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46 publication(s) trouvée(s)
Article scientifique
A sustainable HPLC method coupled with diode array detection for versatile quantification of telmisartan, chlorthalidone and amlodipine in a fixed-dose antihypertensive formulation and dissolution studies
Abstract Cardiovascular diseases, especially hypertension, stand as prominent contributors to global mortality. Hypertension, often referred to as a silent killer …
Article scientifique
Highlighting multicomponent reactions as an efficient and facile alternative route in the chemical synthesis of organic-based molecules: a tremendous growth in the past 5 years
Since Strecker's discovery of multicomponent reactions (MCRs) in 1850, the strategy of applying an MCR approach has been in use …
Article scientifique
Independent concentration extraction as a novel green approach resolving overlapped UV–Vis binary spectra and HPTLC-densitometric methods for concurrent determination of levocloperastine and chlorpheniramine
Abstract Background The proposed research study introduces independent concentration extraction (ICE) as a novel UV–Vis spectrophotometric approach. The approach can …
Article scientifique
Sequential Separation of Anti-Diabetic Drugs in the Presence of Toxic Impurity Using Chromatographic Methods Integrating Green Analytical Chemistry Concept (Impurity Profiling)
Article scientifique
Green chromatographic methods for determination of co-formulated lidocaine hydrochloride and miconazole nitrate along with an endocrine disruptor preservative and potential impurity
Recently, green analytical chemistry (GAC) is a key issue towards the idea of sustainability, the analytical community is focused on …
Article scientifique
Higher sensitive selective spectrofluorometric determination of ritonavir in the presence of nirmatrelvir: application to new FDA approved co-packaged COVID-19 pharmaceutical dosage and spiked human plasma
BACKGROUND: Ritonavir was recently combined with nirmatrelvir in a new approved co-packaged medication form for the treatment of COVID-19. Quantitative …
Article scientifique
Development of a sustainable multianalyte MEKC method for quantitation of the antihyperlipidemic drugs ezetimibe together with three statins. Greenness and whiteness appraisal studies
Implementing powerful and sustainable research that complies with green analytical chemistry (GAC) and white analytical chemistry (WAC) fundamentals can downsize …
Article scientifique
Spectrum subtraction as a complementary method for six resolution techniques resolving overlapping spectra; application to multicomponent veterinary formulation with greenness and whiteness assessment
Abstract Mathematical filtration is an efficient tool to resolve the overlapping spectra of binary mixtures in zero or first order …
Article scientifique
Acriflavine: an efficient green fluorescent probe for sensitive analysis of aceclofenac in pharmaceutical formulations
Acriflavine is a multipurpose drug that shows antibacterial, antiviral, antimalarial, and antifungal activities. The remarkable native fluorescence of acriflavine is …
Article scientifique
Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC–MS/MS profiling of potential impurities: greenness and whiteness evaluation
Abstract Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug …
Article scientifique
Solvent and solvation effects on reactivities and mechanisms of phospho group transfers from phosphate and phosphinate esters to nucleophiles
Organophosphorus esters fulfil many industrial, agricultural, and household roles. Nature has deployed phosphates and their related anhydrides as energy carriers …
Article scientifique
Simultaneous green TLC determination of nirmatrelvir and ritonavir in the pharmaceutical dosage form and spiked human plasma
Quantitative analysis of pharmaceutical compounds up to Nano gram levels is highly recommended to introduce feasible and sensitive tool for …
Article scientifique
Green analytical chemistry and experimental design: a combined approach for the analysis of zonisamide
Abstract Green analytical chemistry principles, as well as experimental design, are a combined approach adopted to develop sensitive reproducible stability …
Article scientifique
Three developed spectrophotometric methods for determination of a mixture of ofloxacin and ornidazole; application of greenness assessment tools
This work is dedicated to the greenness estimation of three proposed spectrophotometric techniques [e.g., ratio difference (RD), mean centering of …
Article scientifique
QSRR modeling of the chromatographic retention behavior of some quinolone and sulfonamide antibacterial agents using firefly algorithm coupled to support vector machine
Quinolone and sulfonamide are two classes of antibacterial agents with an opulent history of medicinal chemistry features that contribute to …
Article scientifique
QSRR modeling of the chromatographic retention behavior for some quinolone and sulfonamide antibacterial agents using firefly algorithm coupled to support vector machine
Abstract Quinolone and sulfonamide are two classes of antibacterial agents that have an opulent history of medicinal chemistry features responsible …
Article scientifique
Lilial (butylphényl méthylpropional): Synthèse et Problématique Sanitaire
La parfumerie moderne naît à la fin du 19me siècle. À cette époque, les parfumeurs commencent à incorporer dans leursformules …
Article scientifique
Design, Characterization, X-ray Single-crystal, Potentiometric Measurements, Molecular Modeling and Biomedical Applications of Thiosemicarbazones
Abstract Series of thiosemicarbazone compounds ((E)-2-((E)-1-(2-(p-tolyl)hydrazono)propan-2-ylidene)hydrazine-1-carbothioamide (TSC1), (E)-N-ethyl-2-((E)-1-(2-(p-tolyl)hydrazono)propan-2-ylidene)hydrazine-1-carbothioamide (TSC2) and (E)-N-phenyl-2-((E)-1-(2-(p-tolyl)hydrazono)propan-2-ylidene)hydrazine-1-carbothioamide)(TSC3) were synthesized and fully characterized by assistance of diverse …
Article scientifique
Eco-friendly analytical methods for the determination of compounds with disparate spectral overlapping: application to antiviral formulation of sofosbuvir and velpatasvir
Abstract Green analytical chemistry is one of the newest trends in analytical chemistry nowadays targeting the concept of green laboratory …
Article scientifique
Simultaneous chromatographic analysis of Sofosbuvir/Ledipasvir in their combined dosage form: an application to green analytical chemistry
Application of green solvents for developing green analytical methodologies has grown dramatically in the past few years. The “more hazardous …