659 publication(s) trouvée(s)
Article scientifique
How fast can PPRV spread? Analyzing the results of an experimental PPRV infection of goats equipped with Ultra-WideBand sensors
Abstract Peste des Petits Ruminants (PPR) is a highly contagious disease affecting goats and sheep. The speed and extent of …
Article scientifique
Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenyan Women Diagnosed with Breast Cancer
ABSTRACT Objective To characterize the mutational landscape and expression profiles of ZNF217, ZNF703, and ZNF750, and assess their clinical relevance …
Article scientifique
In silico design and computational characterization of novel chimeric multiepitope antigens for Mpox serosurveillance
Background The Monkeypox (Mpox) virus is a zoonotic Orthopoxvirus with a global outbreak that began in 2022 and spread to …
Article scientifique
PlantVarFilter: A Comprehensive Pipeline for Variant Filtering and Genome-Wide Association Analysis in Plant Genomics
Abstract Genomic variant analysis is fundamental to understanding the genetic basis of phenotypic traits in plants. However, the increasing volume …
Article scientifique
Synthetic Substitutes as a Conservation Tool: Evaluating Synthetic Leopard Fur for Demand Reduction and Species Recovery
Abstract Providing synthetic substitutes is a widely promoted strategy to shift consumer demand away from wildlife products derived from threatened …
Article scientifique
Uncovering the genetic diversity of the malaria parasite antigen MSP2 across Sub-Saharan Africa
Abstract Genetic diversity in Plasmodium falciparum poses a significant challenge to malaria control and elimination. This is particularly important for …
Article scientifique
Neurocognitive mechanisms of mathematics vocabulary processing in L1 and L2 in South African first graders: An fNIRS study
Abstract Significance To learn mathematics, young children require accurate interpretations of mathematics vocabulary. When school language differs from children’s home …
Article scientifique
Megafauna show pervasive yet distinct affinity to ocean fronts: the urgent need for adaptive conservation in a warming world
Abstract Fronts are ephemeral structures in the ocean that mark the boundaries between water masses of different properties, attracting a …
Article scientifique
Serotypes of Dengue Virus and Kdr Mutations ( F1534C, S989P, V410L, V1016I, and V1016G ) in Aedes aegypti and Aedes albopictus Mosquitoes from the commune of Abomey-Calavi, Southern Benin
Abstract Dengue is a viral infection transmitted by mosquitoes of the Aedes genus, responsible for millions of cases each year. …
Article scientifique
Digital PCR detection of Mycobacterium tuberculosis and HIV-1 co-localization in spinal tuberculosis biopsies
ABSTRACT Background Mycobacterium tuberculosis ( Mtb ) and HIV-1 co-infection in tissues is suggested to favour reciprocal replication, infection and …
Article scientifique
The complete mitochondrial genome of Tunga penetrans and insights into flea phylogeny
Summary Tungiasis, one of the oldest and most neglected tropical diseases endemic to sub-Saharan Africa and the Americas, is caused …
Article scientifique
Impact of Capsicum frutescens (L.) fruit ethanol extract on ibuprofen-induced gastric ulcers: A Wistar rat model
Abstract Gastric ulcers are due to an imbalance between the protective factors like mucus and bicarbonate and offensive factors like …
Article scientifique
Spatially-explicit genomics of An. gambiae s.l uncovers fine-scale population structure and mechanisms of insecticide resistance
Abstract Progress in malaria control in sub-Saharan Africa is stalling, partly due to the spread of insecticide resistance in Anopheles …
Article scientifique
Could malaria mosquitoes be controlled by periodic releases of transgenic mosquitocidal Metarhizium pingshaense fungus? A mathematical modeling approach
Abstract Insect pathogenic fungi offer a promising alternative to chemical insecticides for controlling insecticide resistant mosquitoes. One proposed method involves …
Article scientifique
Edible Bird’s Nest Enhances Memory and Learning in a Rat Model of Sporadic Alzheimer’s Disease
Abstract Alzheimer’s disease (AD) has emerged as a major global health concern, with the glutamate hyperexcitability hypothesis suggesting that synaptic …
Article scientifique
Characterisation of Ornithobacterium hominis colonisation dynamics and interaction with the nasopharyngeal microbiome in a South African birth cohort
Abstract Ornithobacterium hominis is a recently described Gram-negative bacterium that colonises the human nasopharynx and may be associated with poor …
Article scientifique
Protein Kinase C δ: a critical hub regulating macrophage immunomodulatory functions during Mycobacterium tuberculosis infection
Abstract A host-modulating candidate gene involved in putative pathogen-killing pathways, with potential novel therapeutic intervention, Protein Kinase C – δ …
Article scientifique
Transcriptomic Signatures of Neuroinflammation and Adaptive Immunity in the Human SCG During Cardiac Disease: A Bulk RNA-seq Reanalysis
Abstract The superior cervical ganglia (SCG) play an important role in sympathetic and autonomic regulation, yet their molecular adaptations in …
Article scientifique
Quantitative evaluation of dogs as sentinels for Rift Valley fever virus circulation in Madagascar
Abstract Sentinel animals may play a key role in surveillance of zoonotic arbovirus circulation, particularly in developing countries with low …
Article scientifique
Forskolin as a multi-target modulator of the oncogenic PI3K/Akt signaling pathway: An in silico integrative GO/KEGG enrichment analysis and network pharmacology
ABSTRACT Forskolin (FSK), a natural diterpene plant metabolite, exhibits promising anticancer properties, yet its molecular mechanisms remain to be fully …