349 publication(s) trouvée(s)
Article scientifique
Isolation, characterization, and genomic analysis of a novel lytic bacteriophage with potent antibiofilm activity against multidrug-resistant Acinetobacter baumannii
The rapid rise of multidrug-resistant Acinetobacter baumannii (MDR A. baumannii) poses a serious threat in healthcare settings, as these bacteria …
Article scientifique
Malaria exposure history shapes PD-1 expression across human B-cell subsets during acute Plasmodium falciparum infection
BACKGROUND: Repeated malaria exposure shapes humoral immunity in endemic regions. Programmed cell death protein 1 (PD-1) is an inhibitory immune …
Article scientifique
Modular integration of nanopore sequencing, alphafold modeling, and statistical design boosts 1-hydroxyphenazine yield in Pseudomonas aeruginosa strain KAEH25
Abstract This study establishes an integrated genome-to-structure-to-process framework that significantly enhances 1-hydroxyphenazine (1-OH-PHZ) biosynthesis in Pseudomonas aeruginosa KAEH25. Nanopore long-read …
Article scientifique
Correction: Functional and genomic insights into probiotic lactic acid bacteria isolated from the gastrointestinal microbiota of domestic rabbits (Oryctolagus cuniculus)
Article scientifique
Synergistic anti-Helicobacter pylori efficacy of a molecularly identified Limosilactobacillus fermentum isolate in combination with multiple antibiotics
BACKGROUND: Helicobacter pylori (H. pylori) is a Gram-negative gastric pathogen resistant to the acidic stomach environment through urease-mediated neutralization, enabling …
Article scientifique
Molecular and phenotypic profiles of carbapenem- and third-generation cephalosporin-resistant Klebsiella pneumoniae isolates from the fecal microbiota of pediatric patients with COVID-19
Abstract Background Gut colonization with multidrug-resistant (MDR) Klebsiella pneumoniae is commonly associated with an increased risk of extraintestinal infections among …
Article scientifique
Emergence of blaNDM−1 in Pseudomonas aeruginosa ST308 and ST773 from bloodstream infections in Egypt
Abstract Carbapenem-resistant Pseudomonas aeruginosa (CRPA) remains a significant challenge to clinical management, particularly in critically ill hospitalized patients. The present …
Article scientifique
WGS reveals high-risk clones of Pseudomonas aeruginosa harbouring extensive antimicrobial and predicted anti-phage defense systems recovered from diabetic foot ulcer patients in Egypt
Abstract Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus and a leading cause of morbidity, amputation, and …
Article scientifique
Heavy metal tolerance and biosorption efficiency of Lysinibacillus fusiformis SKT23 novel strain for Zn and Cu removal
Bioremediation offers a sustainable strategy for removing heavy metals from water by transforming toxic pollutants into less hazardous forms. In …
Article scientifique
Colonization with Carbapenemase producing Enterobacterales (CPE) and associated alteration in microbiota composition in a tertiary care hospital in Egypt
BACKGROUND: The rising incidence of carbapenemase producing Enterobacterales (CPE)s, represents an urgent health threat due to their raised morbidity and …
Article scientifique
Detection of carbapenem resistance mechanisms in difficult-to-treat Pseudomonas aeruginosa clinical isolates from a tertiary care hospital in Egypt
Abstract Background The increasing incidence of carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a significant global health concern, particularly with the emergence …
Article scientifique
Talaromyces marinus (Eurotiales, Trichocomaceae): a new marine fungus from the Red Sea, Egypt, with distinguished enzymatic capabilities
BACKGROUND: Talaromyces C. R. Benj., is a large and taxonomically important genus within Ascomycota, established to accommodate the teleomorphs of …
Article scientifique
Deciphering the efficacy of staphyloxanthin-encapsulated niosomal nanovesicles to attenuate biofilm formation, quorum sensing, and meropenem persistence in Acinetobacter baumannii
BACKGROUND: Acinetobacter baumannii is the primary cause of persistent opportunistic infections in healthcare settings, recognized as a global priority due …
Article scientifique
Revealing the therapeutic potential of bioactive exopolysaccharide (EPSS10) derived from Streptomyces sp. MAE
Currently, there is an increasing interest in microbial exopolysaccharides (EPSs) due to their diverse functionalities, diversity in chemical structure and …
Article scientifique
Optimizing neutralization strategies for microbial testing of non-sterile pharmaceutical finished products with challenging method suitability
BACKGROUND: Method suitability for microbial limit tests during microbiological quality control (QC) can be a complicated process that requires multiple …
Article scientifique
Bioremediation and optimization of selenate reduction by a novel Bacillus cabrialesii strain (Se1) producing red selenium nanoparticles with potential antibacterial activity
Abstract Background This study aimed to isolate and identify selenate-reducing bacteria from polluted Egyptian soil. The isolated bacteria could be …
Article scientifique
The dual antifungal and antibiofilm activities of β-carotene against multidrug-resistant Candida albicans induce wound healing in a diabetic rat model: an in vitro and in vivo study
BACKGROUND: Diabetes mellitus renders patients susceptible to chronic wounds and fungal infections, such as Candida albicans infections. The treatment of …
Article scientifique
Antimicrobial and antibiofilm activities of culture filtrates from Lactiplantibacillus plantarum isolated from traditional dairy products in Menoufia, Egypt
BACKGROUND: The global rise in multidrug-resistant (MDR) bacterial infections poses a serious threat to public health, largely driven by the …
Article scientifique
Frequency and antimicrobial resistance pattern of non lactose fermenting gram negative rods in neurosurgical patients outlining aminoglycoside resistance genes
BACKGROUND: Non-Fermenting Gram-Negative Rods (NFGNRs) are one of the major causes of hospital-acquired infections (HAIs) with high levels of antibiotic …
Article scientifique
Performance of the low-cost phenotypic thin-layer agar MDR/XDR-TB Colour Test (first generation, 1G, Color Plate Test) for identifying drug-resistant Mycobacterium tuberculosis isolates in a resource-limited setting
BACKGROUND: The accessible, easy to use and timely, diagnosis of tuberculosis (TB) drug-susceptibility, is often challenging, particularly in resource-constrained settings. …
1 / 18
Suivant →