41 publication(s) trouvée(s)
Article scientifique
Harnessing data science to control non-communicable diseases in Africa: a systematic review and gap analysis
BACKGROUND: Data science methods can provide novel and pragmatic approaches for preventing and controlling non-communicable diseases (NCDs) in Africa. This …
Article scientifique
Multimorbidity in adolescents in sub-Saharan Africa: a systematic review
BACKGROUND: Individuals living with two or more long-term health conditions, known as multimorbidity, experience poorer physical and mental well-being due …
Article scientifique
Geospatial analysis reveals similar HIV-1 drug resistance patterns among antiretroviral therapy-experienced children and adolescents (0-17 years) of South Africa
BACKGROUND: HIV-1 drug resistance (HIVDR) complicates antiretroviral therapy (ART) in children and adolescents living with HIV (CALWH), particularly in high-prevalence …
Article scientifique
Development and validation of the lifetime sense of safety scale in Kenyan adults
BACKGROUND: Safety supports psychological wellbeing and potentially shapes brain aging yet existing scales overlook cumulative lifespan safety experiences. METHODS: To …
Article scientifique
Inequalities and determinants of unmet need for SARS-CoV-2 testing in Ghana, Burkina Faso and Madagascar (2020 – 2021)
BACKGROUND: Many sub-Saharan African countries faced considerable challenges in containing SARS-COV-2 transmission due to limited capacity to test and treat …
Article scientifique
Modelling the impact of increasing tuberculosis treatment coverage and addressing determinants of risk in men
BACKGROUND: Globally, the burden of tuberculosis falls more on men than women and children, and there are large gaps between …
Article scientifique
Early-life immunological and microbial differences between East African and North European children
BACKGROUND: The urbanization of African populations adopting Westernized lifestyles might be connected to changes in microbial exposure and immune system …
Article scientifique
Modelling of onchocerciasis-associated skin and ocular disease and the impact of ivermectin treatment
BACKGROUND: Despite decades of control interventions in sub-Saharan Africa, morbidity associated with Onchocerca volvulus infection still exerts a substantial burden …
Article scientifique
Antigen heterogeneity in the development and clinical validation of a multiplexed urine test for tuberculosis
BACKGROUND: Tuberculosis (TB) is one of the leading causes of death worldwide, even though it is curable using antibiotics. Most …
Article scientifique
Towards a nomenclature of health services for implementing universal health coverage in low- and middle-income countries
BACKGROUND: Achieving Universal Health Coverage (UHC) in low- and middle-income countries (LMICs) requires a robust digital infrastructure capable of monitoring …
Article scientifique
Host proteins associated with strong neutralizing SARS-CoV-2 antibody responses in a South African cohort
BACKGROUND: Severe Covid-19 leads to higher neutralizing antibody levels, a key correlate of protection. However, the host proteins associated with …
Article scientifique
Host response biomarkers of tuberculosis recurrence and treatment failure
BACKGROUND: Accurate detection of tuberculosis (TB) treatment failure and recurrence can improve disease control, but current sputum-based monitoring tools pose …
Article scientifique
A multivariate decomposition analysis of drivers of overweight and obesity among Ghanaian women
BACKGROUND: Overweight and obesity are rising globally, with Ghana experiencing significant increases among women over the past two decades, raising …
Article scientifique
Decomposing wealth-based inequalities in ideal cardiovascular health in Kenya
BACKGROUND: This study examined wealth-related inequalities in ideal cardiovascular health (iCVH), as defined by the 2010 American Heart Association guideline, …
Article scientifique
Development and validation of a multivariable model to identify candidates for oral cancer screening in Nigeria
BACKGROUND: Oral cancer screening can potentially improve the prevention and early detection of tumors if targeted toward at-risk individuals in …
Article scientifique
Addressing infectious diseases in Africa by accelerating drug discovery through data science
Despite being rich in natural resources and scientific talent, Africa continues to bear a staggering infectious disease burden. Historically, health …
Article scientifique
First imported cases of MPXV Clade Ib from Goma, Democratic Republic of the Congo
BACKGROUND: The ongoing mpox outbreaks in the Democratic Republic of the Congo (DRC) resulted in >71,000 suspected cases from 01 …
Article scientifique
Metagenomic complexity of high, seasonal transmission of Plasmodium spp. in asymptomatic carriers in Northern Sahelian Ghana
BACKGROUND: Mixed-species, mixed-strain plasmodia infections are known to occur in humans in malaria endemic areas. It may be surprising that …
Article scientifique
Long-term trends in obesity and overweight in women in Ghana from 2003–2023
BACKGROUND: In Ghana, overweight and obesity prevalence among women (20-49 years) reached 50% in 2022, increasing from 40% in 2014. …
Article scientifique
AI and digital health for childhood cancer care in Ghana
Childhood cancers, though relatively rare compared to adult cancers, present a major global health challenge 1 . Each year, about …
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