471 publication(s) trouvée(s)
Article scientifique
The association of systemic inflammation and cognitive functions of pre-school aged children residing in a Schistosoma haematobium endemic area in Zimbabwe
Background: Cognitive function is negatively impacted by schistosomiasis and might be caused by systemic inflammation which has been hypothesized to …
Éditorial
Editorial: The role of vitamin D as an immunomodulator
The role of vitamin D as an immunomodulatorThe metabolism and immunomodulatory role of vitamin D: An abbreviated overview Considered as …
Article scientifique
Autosomal recessive IL12RB1 mutation: A case report of a Sudanese child and his father
Introduction Mendelian susceptibility to mycobacterial disease (MSMD) is a rare inherited condition characterized by selective susceptibility to weakly virulent mycobacteria, …
Article scientifique
Development of a dual vaccine against East Coast fever and lumpy skin disease
East Coast fever is an acute bovine disease caused by the apicomplexan parasite Theileria parva and is regarded as one …
Article scientifique
Pre-existing immunity to SARS-CoV-2 before the COVID-19 pandemic era in Cameroon: A comparative analysis according to HIV-status
Background: The lower burden of COVID-19 in tropical settings may be due to preexisting cross-immunity, which might vary according to …
Article scientifique
Persistent immune activation and altered gut integrity over time in a longitudinal study of Ugandan youth with perinatally acquired HIV
Introduction: Perinatally acquired HIV infection (PHIV) occurs during a critical window of immune development. We investigated changes in systemic inflammation …
Article scientifique
Rapid, early, and potent Spike-directed IgG, IgM, and IgA distinguish asymptomatic from mildly symptomatic COVID-19 in Uganda, with IgG persisting for 28 months
Introduction: Understanding how spike (S)-, nucleoprotein (N)-, and RBD-directed antibody responses evolved in mild and asymptomatic COVID-19 in Africa and …
Article scientifique
Optimisation and Validation of a conventional ELISA and cut-offs for detecting and quantifying anti-SARS-CoV-2 Spike, RBD, and Nucleoprotein IgG, IgM, and IgA antibodies in Uganda
There is an urgent need for better immunoassays to measure antibody responses as part of immune-surveillance activities and to profile …
Article scientifique
The role of Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target
Metastatic breast cancer is one of the most common and well-known causes of death for women worldwide. The inflammatory tumor …
Éditorial
Editorial: Immuno-diagnosis of active tuberculosis; are we making progress?
Editorial on the Research Topic Immuno-diagnosis of active tuberculosisActive tuberculosis (ATB) diagnosis suffers from several knowledge gaps and challenges, including …
Article scientifique
Rs205764 and rs547311 in linc00513 may influence treatment responses in multiple sclerosis patients: A pharmacogenomics Egyptian study
Background: Multiple sclerosis (MS) is characterized by a complex etiology that is reflected in the lack of consistently predictable treatment …
Éditorial
Editorial: T cell exhaustion; mechanisms of induction, modulation, and recovery
EDITORIAL article Front. Immunol., 05 January 2023Sec. Immunological Memory Volume 13 - 2022 | https://doi.org/10.3389/fimmu.2022.1122530
Article scientifique
Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever
Nanoparticle vaccines usually prime stronger immune responses than soluble antigens. Within this class of subunit vaccines, the recent development of …
Article scientifique
Diagnostic challenge in a series of eleven patients with hyper IgE syndromes
Hyper IgE syndromes (HIES) is a heterogeneous group of Inborn Errors of Immunity characterized by eczema, recurrent skin and lung …
Article scientifique
The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID- 19) caused by severe acute respiratory syndrome coronavirus 2 …
Article scientifique
Immunologic, metabolic and genetic impact of diabetes on tuberculosis susceptibility
Due to the increasing prevalence of diabetes mellitus (DM) globally, the interaction between DM and major global diseases like tuberculosis …
Article scientifique
Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease
Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global mortality, with three million deaths reported annually. This impact is …
Article scientifique
Protective roles and protective mechanisms of neutralizing antibodies against SARS-CoV-2 infection and their potential clinical implications
Neutralizing antibodies (NAbs) are central players in the humoral immunity that defends the body from SARS-CoV-2 infection by blocking viral …
Article scientifique
IgY antibodies: The promising potential to overcome antibiotic resistance
Antibiotic resistant bacteria are a growing threat to global health security. Whilst the emergence of antimicrobial resistance (AMR) is a …
Éditorial
Editorial: Host immune evasion by Mycobacterium tuberculosis: Current updates
Host immune evasion by Mycobacterium tuberculosis: Current updatesMycobacterium tuberculosis (M.tb) can become a long-term infection by evading the host's immune …