471 publication(s) trouvée(s)
Article scientifique
Immunological response and implications of Ad26.COV2. S (Janssen COVID-19 vaccine) vaccine in diabetic patients: a prospective cohort study in Ethiopia
Introduction: Patients with Diabetes are at increased risk of severe COVID-19 and death, thus, it is imperative to provide them …
Article scientifique
Retrospective analysis of sex-disaggregated immune responses to ALVAC-HIV and bivalent subtype C gp120/MF59 HIV vaccines
Introduction Generally, individuals assigned female at birth (AFAB) develop greater immunogenicity to various vaccines than individuals assigned male at birth …
Article scientifique
Metabolic and immune consequences of antibiotic related microbiome alterations during first-line tuberculosis treatment in Bamako, Mali
Background: Individuals with a history of tuberculosis (TB) treatment are at a higher risk of experiencing a recurrent episode of …
Article scientifique
Expression of salivary hepcidin and its inducer, interleukin 6 as well as type I interferons are significantly elevated in infants with poor oral rotavirus vaccine take in South Africa
Background: The metabolism of nutritional iron, required by viruses to replicate and proliferate, is regulated by hepcidin, a peptide hormone …
Article scientifique
Anti-HMGCR myopathy: a first case report from North Africa and literature insights
Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is a rare idiopathic inflammatory myopathy characterized by severe muscle damage and minimal extra-muscular involvement. …
Article scientifique
The promise of PD1/PDL1 targeted immunotherapy in locally advanced cervical cancer: a game-changer for patients outcome?
Locally advanced cervical cancer remains a significant therapeutic challenge, with high rates of recurrence and metastasis despite advances in chemoradiation. …
Article scientifique
Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19
Introduction: Little is known about the acute and long-term sequelae of COVID-19 and its pathophysiology in African patients, who are …
Article scientifique
Medicinal plants: bioactive compounds, biological activities, combating multidrug-resistant microorganisms, and human health benefits - a comprehensive review
In recent years, medicinal plants have gained significant attention in modern medicine due to their accessibility, affordability, widespread acceptance, and …
Éditorial
Editorial: Immunesenescence in innate immune cells and disease development
Population ageing is accelerating worldwide. As per the WHO, the world's population over 60 years will double by 2050 with …
Article scientifique
Cytokine profiles and CD4 counts in HIV-positive individuals with cysticercosis: implications for sex-specific immune responses in co-endemic regions of Tanzania
Introduction: T-cell counts, and cysticercosis infection status in HIV-positive individuals in Tanzania's southern highlands. Methods: We conducted a cross-sectional study …
Article scientifique
Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages
Introduction Macrophages play a crucial immunological role in maintaining pregnancy. Placental malaria infection may cause dysfunction in decidual macrophages which …
Erratum
Corrigendum: Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients
• please read through all the templates before choosing • pick the most relevant text template(s) from the following page …
Éditorial
Editorial: Novel reliable approaches for prediction and clinical decision-making in cancer
Although significant progress has been made in recent decades in understanding the development and progression of cancer, cancer remains one …
Article scientifique
Assessing the effects of diabetes mellitus on the monocyte-to-lymphocyte ratio and the QuantiFERON-TB gold plus assays for tuberculosis treatment monitoring: a prospective cohort study
Diabetes mellitus (DM) is an important risk factor for the development of active tuberculosis (TB). QuantiFERON-TB Gold Plus (QFT-P), white …
Article scientifique
Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function
One of the major consequences of schistosomiasis is its impact on brain function, and despite its severity, the underlying mechanism(s) …
Article scientifique
Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1–infected women is associated with lower viral loads
Sex differences play a role in the pathogenesis of a number of viral diseases. In HIV-1, several studies have reported …
Article scientifique
Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma
Introduction: New biomarkers are urgently needed to detect pancreatic ductal adenocarcinoma (PDAC) at an earlier stage for individualized treatment strategies …
Article scientifique
Biochemical profiles of patients with COVID-19 during the first and second waves in Ethiopia
Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2. Nasopharyngeal swabs (NP …
Article scientifique
Gene expression of tight junctions in foreskin is not affected by HIV pre-exposure prophylaxis
Introduction Tight junctions (TJs) serve as permeability filters between the internal and external cellular environment. A large number of proteins …
Article scientifique
Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients
The impact of human pulmonary tuberculosis (TB) on the bioenergetic metabolism of circulating immune cells remains elusive, as does the …