471 publication(s) trouvée(s)
Article scientifique
ProC6C, a novel multi-stage malaria vaccine, elicits functional antibodies against the minor and central repeats of the Circumsporozoite Protein in human adults
Introduction ProC6C is a multi-stage malaria vaccine which includes Plasmodium falciparum Circumsporozoite Protein (PfCSP), Pfs48/45 and Pfs230 sequences, designed to …
Article scientifique
Defective proviruses significantly impact viral transcription and immune activation in men and women with HIV-1 subtype C in rural South Africa
Introduction: T cell count, and immune activation before and during 96 weeks of successful antiretroviral therapy (ART). Methods: Eighty-two participants …
Article scientifique
Extracellular vesicles: immunomodulation, diagnosis, and promising therapeutic roles for rheumatoid arthritis
Extracellular vesicles (EV) can be produced as part of pathology and physiology with increased amounts in pathological conditions. EVs can …
Article scientifique
Immunoregulatory protein B7-H3 upregulated in bacterial and viral infection and its diagnostic potential in clinical settings
Bacterial and viral infections cause a huge burden to healthcare settings worldwide, and mortality rates associated with infectious microorganisms have …
Article scientifique
Circulatory microRNAs and proinflammatory cytokines as predictors of lupus nephritis
Introduction: Lupus nephritis (LN) is one of the most prevalent severe organ manifestations of systemic lupus erythematosus (SLE), impacting 70% …
Article scientifique
Investigating tumor immunogenicity in breast cancer: deciphering the tumor immune response to enhance therapeutic approaches
The interplay between immune cells and malignant cells represents an essential chapter in the eradication of breast cancer. This widely …
Article scientifique
Plasma adenosine deaminase-1 and -2 activities are lower at birth in Papua New Guinea than in The Gambia but converge over the first weeks of life
Introduction: Dynamic cellular and molecular adaptations in early life significantly impact health and disease. Upon birth, newborns are immediately challenged …
Article scientifique
Peripheral NK cell phenotypic alteration and dysfunctional state post hepatitis B subviral particles stimulation in CHB patients: evading immune surveillance
Background: The relationship between chronic hepatitis B (CHB) infection and natural killer (NK) cell dysfunction is well-established, but the specific …
Article scientifique
Variation within the non-coding genome influences genetic and epigenetic regulation of the human leukocyte antigen genes
Variation within the non-coding genome may influence the regulation and expression of important genes involved in immune control such as …
Article scientifique
HBHA induces IL-10 from CD4+ T cells in patients with active tuberculosis but IFN-γ and IL-17 from individuals with Mycobacterium tuberculosis infection
Background To effectively control tuberculosis (TB), it is crucial to distinguish between active TB disease and latent TB infection (LTBI) …
Article scientifique
Pre-vaccination Schistosoma mansoni and hookworm infections are associated with altered vaccine immune responses: a longitudinal analysis among adolescents living in helminth-endemic islands of Lake Victoria, Uganda
Background Variations in vaccine responses have been observed between populations. A role for helminth infections has been proposed due to …
Article scientifique
Decoding the secret of extracellular vesicles in the immune tumor microenvironment of the glioblastoma: on the border of kingdoms
Over the last decades, extracellular vesicles (EVs) have become increasingly popular for their roles in various pathologies, including cancer and …
Article scientifique
Acquisition of anti-phosphatidylserine IgM and IgG antibodies by infants and their mothers over time in Uganda
Background Production of anti-phosphatidylserine (anti-PS) antibodies has been associated with malaria and can aggravate pathology. How these autoantibodies develop during …
Article scientifique
Flow cytometry-based diagnostic approach for inborn errors of immunity: experience from Algeria
Purpose: In this study, we retrospectively reviewed the use of flow cytometry (FCM) in the diagnosis of inborn errors of …
Article scientifique
Regulatory T cell homing and activation is a signature of neonatal sepsis
Regulatory T cells (Treg) play a prominent role in utero tolerating non-inherited maternal antigens and in regulating immune responses against …
Article scientifique
Development and validation of novel keloid-derived immortalized fibroblast cell lines
Keloids are a common connective tissue disorder with an ill-understood etiopathogenesis and no effective treatment. This is exacerbated because of …
Article scientifique
Bi-isotype immunoglobulins enhance antibody-mediated neutrophil activity against Plasmodium falciparum parasites
Background: Malaria remains a major global health priority, and monoclonal antibodies (mAbs) are emerging as potential new tools to support …
Article scientifique
Hesperidin - loaded PVA/alginate hydrogel: targeting NFκB/iNOS/COX-2/TNF-α inflammatory signaling pathway
Introduction: Skin injuries represent a prevalent form of physical trauma, necessitating effective therapeutic strategies to expedite the wound healing process. …
Erratum
Corrigendum: Microbiota dynamics, metabolic and immune interactions in the cervicovaginal environment and their role in spontaneous preterm birth
[This corrects the article DOI: 10.3389/fimmu.2023.1306473.].
Article scientifique
Identification of conserved cross-species B-cell linear epitopes in human malaria: a subtractive proteomics and immuno-informatics approach targeting merozoite stage proteins
Human malaria, caused by five Plasmodium species ( P. falciparum, P. vivax, P. malariae, P. ovale , and P. knowlesi …