486 publication(s) trouvée(s)
Article scientifique
Practice Guidelines for Clinical Pharmacists in Middle to Low Income Countries
The profession of pharmacy is maturing as a clinical profession in South Africa and has experienced significant development over the …
Article scientifique
Mining Sudanese Medicinal Plants for Antiprotozoal Agents
Neglected tropical diseases are major health hazards in developing countries. Annually, up to thirty million people are affected by either …
Article scientifique
Accumulation of TB-Active Compounds in Murine Organs Relevant to Infection by Mycobacterium tuberculosis
Tuberculosis (TB), the leading cause of death due to an infectious agent, requires prolonged and costly drug treatments. With the …
Article scientifique
Supplement With Calcium or Alendronate Suppresses Osteopenia Due to Long Term Rabeprazole Treatment in Female Mice: Influence on Bone TRAP and Osteopontin Levels
BACKGROUND AND PURPOSE: Rabeprazole, a proton pump inhibitor (PPIs) is much endorsed to patients with increased gastric acidity. PPIs were …
Article scientifique
Available Evidence and Ongoing Clinical Trials of Remdesivir: Could It Be a Promising Therapeutic Option for COVID-19?
The novel coronavirus strain, SARS-CoV-2, the causative agent of COVID-19 emerged in Wuhan, China, in December 2019 and has rapidly …
Article scientifique
Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus
Leishmaniasis is a neglected tropical disease caused by the parasitic protozoa, Leishmania. Approximately, 350 million people are at risk of …
Article scientifique
Evaluation of Medication Use Pattern Among Patients Presenting to the Emergency Department of Hiwot Fana Specialized University Hospital, Using WHO Prescribing Indicators
BACKGROUND: Ensuring rational drug use requires ongoing evaluation of drug prescribing, dispensing, and use by patients. Health care providers working …
Article scientifique
Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients
Cyclophosphamide (CPA) containing chemotherapy regimen is the standard of care for breast cancer treatment in sub-Saharan Africa. Wide inter-individual variations …
Article scientifique
In Vitro Assessment of the Interaction Potential of Ocimum basilicum (L.) Extracts on CYP2B6, 3A4, and Rifampicin Metabolism
Ocimum basilicum L. or basilicum is a common culinary herb, used as a traditional medicine for various medical conditions including …
Article scientifique
Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics
The harmful impact of xenobiotics on the environment and human health is being more widely recognized; yet, inter- and intraindividual …
Article scientifique
Modulation of the Endothelin System in Colorectal Cancer Liver Metastasis: Influence of Epigenetic Mechanisms?
Targeting of endothelin system genes is a promising strategy in cancer therapy. The modulation of these genes was explored in …
Article scientifique
1H-NMR Metabolomics and LC-MS Analysis to Determine Seasonal Variation in a Cosmeceutical Plant Leucosidea sericea
Leucosidea sericea is an evergreen shrub belonging to the Rosaceae family with previous studies that indicated that L. sericea extracts …
Article scientifique
Hepatoprotective Effect of Cranberry Nutraceutical Extract in Non-alcoholic Fatty Liver Model in Rats: Impact on Insulin Resistance and Nrf-2 Expression
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a pathological accumulation of triglycerides (TGs) in the hepatocyte in the absence of …
Article scientifique
Review of Ongoing Activities and Challenges to Improve the Care of Patients With Type 2 Diabetes Across Africa and the Implications for the Future
BACKGROUND: There has been an appreciable increase in the number of people in Africa with metabolic syndrome and Type 2 …
Article scientifique
Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations
Efavirenz-based combination antiretroviral-therapy (cART) is the recommended regimen during tuberculosis (TB) therapy. In a multi-national parallel prospective-cohort study, we investigated …
Article scientifique
Implementation of Health Technology Assessment in the Middle East and North Africa: Comparison Between the Current and Preferred Status
INTRODUCTION: Implementation of health technology assessment (HTA) is still in an early stage with some heterogeneity in the Middle East …
Compte rendu de lecture
Book Review: Herbal Principles in Cosmetics: Properties and Mechanisms of Action
BOOK REVIEW article Front. Pharmacol., 09 January 2020Sec. Ethnopharmacology Volume 10 - 2019 | https://doi.org/10.3389/fphar.2019.01513
Article scientifique
Endothelin-1/Nitric Oxide Ratio as a Predictive Factor of Response to Therapy With Terlipressin and Albumin in Patients With Type-1 Hepatorenal Syndrome
Background and Purpose: Predictors of response to type-1 hepatorenal syndrome (HRS) therapy are urgently needed. This study’s purpose is to …
Article scientifique
Validation and Reliability of Healthcare Workers’ Knowledge, Attitude, and Practice Instrument for Uncomplicated Malaria by Rasch Measurement Model
Background: This study assessed the validity and reliability of healthcare workers’ knowledge, attitudes and practices instrument for uncomplicated malaria (HKAPIUM) …
Article scientifique
Molecular Mechanisms of Action of Genistein in Cancer: Recent Advances
Background: Genistein is one among the several other known isoflavones that can be found in different soybeans and soy products. …