486 publication(s) trouvée(s)
Article scientifique
Randomized, double-blind, placebo-controlled pilot study of metformin as an adjunctive therapy in Parkinson’s disease
Background Parkinson’s disease (PD) is caused by the progressive loss of dopaminergic neurons in the substantia nigra. Neuroinflammation is considered …
Article scientifique
Drug-therapy-related problems and pharmacist interventions in the medical ward in northeast Ethiopia: focus on types, acceptability, and impacts
Objective: This study aims to identify drug-therapy-related problems, possible interventions, acceptability, and impacts of the interventions among patients admitted to …
Article scientifique
Incidence and determinants of excessive weight gain in people living with HIV initiating tenofovir, lamivudine, and dolutegravir-based therapy: a multicenter retrospective study in northwest Ethiopia
Background: The incidence and nature of excessive weight gain associated with antiretroviral treatment using tenofovir, lamivudine, and dolutegravir based regimens …
Article scientifique
Exploring indigenous knowledge and practices of the Gurage community on the biosystematics and utilization of Enset landraces for bone fracture and regeneration: the case of Gurage Zone, central Ethiopia region
Background: ) is a crucial perennial crop in Ethiopia for both food and medicine. The indigenous knowledge and practices of …
Article scientifique
Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats
Introduction: Gentamicin (GM) is a frequently used aminoglycoside for managing serious illnesses; nonetheless, renal complications limit its use. Bee venom …
Article scientifique
Regulatory challenges of digital health: the case of mental health applications and personal data in South Africa
Introduction: This study explores the regulatory challenges posed by digital mental health applications in South Africa, particularly regarding the collection …
Article scientifique
Post-treatment of rat aflatoxicosis by camel milk and silymarin
Background: Aflatoxins are highly potent mycotoxins that can seriously harm the health of humans and a variety of animal species. …
Article scientifique
Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic pathways and BDNF expression
Ethnopharmacological studies revealed that the leaves and stems of Mimosa pudica L. (Fabaceae) are widely used for the treatment of …
Article scientifique
Time in the therapeutic range, bleeding event, and their determinants in older patients with atrial fibrillation on warfarin in Ethiopia: multicenter cross-sectional study
Background: Atrial fibrillation (AF) poses significant thromboembolism and bleeding risks, especially in older adults. Warfarin continues to be a primary …
Article scientifique
Leveraging AI to optimize vaccines supply chain and logistics in Africa: opportunities and challenges
Examining the current situation of the vaccine supply chain in Africa, the article highlights the importance of AI technologies while …
Article scientifique
Cost-effectiveness of tyrosine kinase inhibitor treatment strategies for chronic myeloid leukemia in South Africa
Background: The treatment of chronic myeloid leukemia through tyrosine kinase inhibitors (TKIs) has achieved promising efficacy and safety outcomes, however …
Article scientifique
Evaluation of the antidiarrheal activity of the 80% hydromethanolic crude extract and solvent fractions of Terminalia brownii Fresen (Combretaceae) leaves in Swiss Albino mice
Background Although diarrhea is a preventable disease, it continues to have a significant impact on global health, with the burden …
Article scientifique
Kleinia (Asteraceae): comprehensive review of ethnomedicinal uses, phytochemical profiles, ethnopharmacological applications, and toxicological insights
Kleinia is a genus of over 50 species that are commonly used in primary care in several countries. This study …
Article scientifique
Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives
Background: The World Health Organization (WHO) reports that a significant portion of the global population relies on traditional herbal medicine …
Article scientifique
Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways
Introduction Methotrexate (MTX) is a frequently utilized anti-inflammatory and anticancer agent. Its potential liver and lung toxicity often limits its …
Erratum
Corrigendum: Ethnobotanical survey and scientific validation of liver-healing plants in northeastern Morocco
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Éditorial
Editorial: Data governance in African health research: ELSI challenges and solutions
A clear legal and data management framework is crucial for protecting privacy and upholding ethical standards in health research. This …
Article scientifique
Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress
Objectives: Hepatotoxicity is a severe outcome of methotrexate (MTX) therapy, limiting its clinical use and contributing to its related morbidity …
Article scientifique
Sustainable integration of artificial intelligence and machine learning approaches within the African infectious disease vaccine research and development ecosystem
Artificial Intelligence and Machine Learning (AI/ML) techniques, including reverse vaccinology and predictive models, have already been applied for developing vaccine …
Article scientifique
In vitro anti-prostate cancer efficacy and phytochemical composition of the dichloromethane and ethyl acetate leaf extracts of Vitex doniana (sweet)
Background Prostate cancer is a significant global health concern, particularly among ageing male populations, with a disproportionately higher burden in …