1722 publication(s) trouvée(s)
Article scientifique
Modelling the effects of precipitation and temperature on malaria incidence in coastal and western Kenya
BACKGROUND: Malaria continues to plague sub-Saharan Africa despite great efforts geared towards its mitigation. In Kenya alone, 70% of the …
Article scientifique
Rethinking malaria elimination: a perspective on challenges and solutions in Angola
BACKGROUND: Multiple challenges hinder malaria control in Angola, including climatic variability, ineffective vector control, population displacement, socioeconomic inequalities, and increasing …
Article scientifique
Hidden reservoirs of infection: prevalence and risk factors of asymptomatic malaria in a high-endemic region of Zambia
BACKGROUND: Malaria remains a significant global health challenge, particularly in sub-Saharan Africa (SSA), where asymptomatic cases contribute to ongoing transmission …
Article scientifique
Subnational introduction of the RTS,S/AS01E malaria vaccine into routine immunization: experience and lessons from the three pilot countries
BACKGROUND: (RTS,S) malaria vaccine for the prevention of Plasmodium falciparum malaria in children living in endemic areas informed by evidence …
Article scientifique
Assessing the accuracy of the recording and reporting of malaria rapid diagnostic test results in four African countries: methods and key results
BACKGROUND: Rapid diagnostic test (RDT) results are the foundation of both case management and malaria surveillance across sub-Saharan Africa. However, …
Article scientifique
A survey of indoor and outdoor Anopheles density, species composition and circumsporozoite rate of malaria vectors on the Bijagós Archipelago, Guinea-Bissau
BACKGROUND: The malaria-endemic Bijagós Archipelago is situated 50 km off the coast of mainland Guinea-Bissau. It is a seasonal malaria …
Article scientifique
Performance of molecular inversion probe DR23K and Paragon MAD4HatTeR Amplicon sequencing panels for detection of Plasmodium falciparum mutations associated with antimalarial drug resistance
Abstract Background Molecular surveillance of drug-resistant Plasmodium falciparum is crucial for malaria control in endemic regions. Two targeted-resequencing tools, the …
Article scientifique
Bringing malaria diagnosis and treatment closer to the people: economic rationale for expanding malaria community case management to all ages in a rural district in Madagascar
BACKGROUND: Expanding malaria community case management (mCCM) to all ages could shift the point-of-care to the community leading to improved …
Article scientifique
Adherence to anti-malarials among patients diagnosed with malaria in East Africa: a systematic review and meta-analysis
BACKGROUND: East Africa continues to bear a significant share of the global malaria burden, despite its commitment to the malaria …
Article scientifique
Field evaluation of the Bioline Malaria Ag P.f/Pan rapid diagnostic test: causes of microscopy discordance and performance in Uganda
BACKGROUND: Histidine Rich Protein 2 (HRP2)/pan-Lactate Dehydrogenase (pLDH) combination rapid diagnostic tests (RDTs) may address the shortcomings of RDTs that …
Article scientifique
Spatiotemporal analysis of Anopheles gambiae larval sites and malaria transmission in Djilakh, Central Senegal
BACKGROUND: The progress made against malaria has resulted in a nationwide reduction of the disease burden in Senegal. The observed …
Article scientifique
Multiplex LC–MS/MS assay for simultaneous quantification of artesunate and its active metabolite dihydroartemisinin with pyronaridine, proguanil, cycloguanil, and clindamycin in pharmacokinetic studies
BACKGROUND: Malaria, especially caused by Plasmodium falciparum, remains a major global health concern, particularly in sub-Saharan Africa. To combat rising …
Article scientifique
Spatial and temporal variation of malaria incidence in children under 10 years in a pyrethroid-resistant vector area in southern Benin
BACKGROUND: Spatial and temporal identification of malaria-endemic areas is a key component of vector-borne disease control. Strategies to target the …
Article scientifique
Seasonal malaria chemoprevention in northern Mozambique: a cost-effectiveness analysis
BACKGROUND: Malaria is endemic in Mozambique and one of the leading causes of death in children under 5 years old. …
Article scientifique
Socio-economic inequalities in malaria prevalence among under-five children in Ghana between 2016 and 2019: a decomposition analysis
BACKGROUND: In a country with limited and unequally distributed resources, and plagued with malaria annually, under-five children are severely affected …
Article scientifique
Stable Plasmodium falciparum merozoite surface protein-1 allelic diversity despite decreasing parasitaemia in children with multiple malaria infections
Abstract Background Individuals experiencing recurrent malaria infections encounter a variety of alleles with each new infection. This ongoing allelic diversity …
Article scientifique
Correction: Understanding malaria treatment patronage from informal healthcare providers in Nigerian urban settlements: insights from community members and providers
Article scientifique
Estimating the potential impact of surveillance test-and-treat posts to reduce malaria in border regions in sub-Saharan Africa: a modelling study
Abstract Background The last malaria cases in near-elimination settings are often found in international border regions due to the presence …
Article scientifique
Preferential transmission of minority and drug-resistant clones in polyclonal infections in Mali
BACKGROUND: In polyclonal human malaria infections, the roles of individual clones in human-to-mosquito transmission and their relative transmissibility remain poorly …
Article scientifique
Daytime and public space exposure to Anopheles funestus bites in Western Province, Zambia: implications for malaria surveillance and control
BACKGROUND: Western Province, Zambia experiences persistent and residual malaria transmission despite high household coverage of core vector control interventions. Standard …