1722 publication(s) trouvée(s)
Article scientifique
Strengthening local capacity for mathematical modelling in low- and middle-income countries: the process and lessons learnt in implementing the first cohort of Nigeria malaria modelling fellowships
BACKGROUND: Mathematical modelling plays a crucial role in understanding malaria epidemiology and evaluating anti-malarial interventions. In sub-Saharan Africa, National Malaria …
Article scientifique
MALDI-TOF mass spectrometry combined with machine learning algorithms to identify protein profiles related to malaria infection in human sera from Côte d’Ivoire
BACKGROUND: In sub-Saharan Africa, Plasmodium falciparum is the most prevalent species of malaria parasites. In endemic areas, malaria is mainly …
Article scientifique
Estimating malaria antigen dynamics and the time to negativity of next-generation malaria rapid diagnostic tests
BACKGROUND: Rapid diagnostic tests (RDTs) used to diagnose Plasmodium falciparum predominantly target the antigen Histidine Rich Protein 2 (HRP2) exclusively. …
Article scientifique
Maximizing horizontal transmission through mating: increased mating frequency and mating competitiveness associated with Microsporidia MB-infected Anopheles arabiensis males
Abstract Background Microsporidia MB is a naturally occurring symbiont in Anopheles arabiensis mosquitoes that inhibits the development of Plasmodium. It …
Article scientifique
Performance of rapid diagnostic tests, microscopy, and qPCR for detection of Plasmodium parasites among community members with or without symptoms of malaria in villages located in North-western Tanzania
BACKGROUND: Despite the implementation of different control interventions, Plasmodium parasite infections in the communities (among asymptomatic and symptomatic individuals) still …
Article scientifique
Urban malaria in sub-Saharan Africa: a scoping review of epidemiologic studies
BACKGROUND: Malaria control in African cities faces challenges mainly due to unplanned urbanization and the spread of Anopheles stephensi. Urbanization …
Article scientifique
Modelling child anaemia and co-existing infections using log-linear models
Abstract Background Uganda grapples with a considerable anaemia-malaria-fever burden, reporting approximate prevalence rates as high as 33%, 34%, and 37% …
Article scientifique
Prevalence of malaria and associated factors among febrile cases attending in Soyama Health Centre, Burji Special Woreda, Southern Ethiopia: a retrospective and an institution-based cross-sectional study
BACKGROUND: Burji special Woreda is one of the malaria endemic areas in Southern Ethiopia. The objective of this study was …
Article scientifique
Where is the hard-to-reach population? Spatial analysis from a cross-sectional study on the access to bed net and malaria vaccine in the Lake Victoria Region, Kenya
BACKGROUND: Long-lasting insecticidal nets (LLIN) and vaccines are effective malaria control tools. However, inadequate uptake has been reported in countries …
Article scientifique
Acceptance and affordability of malaria vaccines: issues relating to hesitancy and willingness to pay amongst Nigerian parents of under-five children
BACKGROUND: With the recent approval of the malaria vaccine by the World Health Organization, it is expected that global acceptance …
Article scientifique
Plasmodium falciparum gametocyte burden in a Tanzanian heterogeneous transmission setting
BACKGROUND: Malaria transmission depends on the presence of gametocytes in the peripheral blood of infected human hosts. Understanding malaria infectious …
Article scientifique
Phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula Province, Mozambique
BACKGROUND: Seasonal malaria chemoprevention (SMC) is a highly effective intervention for malaria prevention in high burden areas with seasonal transmission, …
Article scientifique
Prevalence of malaria and associated factors among febrile children under 15 years at Bududa General Hospital, Eastern Uganda
BACKGROUND: A significant portion of malaria-related deaths occur in Africa, and Uganda is an endemic region where malaria remains a …
Article scientifique
Enhancing the uptake of intermittent preventive treatment for malaria in pregnancy: a scoping review of interventions and gender-informed approaches
BACKGROUND: Malaria infection in pregnancy is a critical determinant of maternal and neonatal health outcomes in endemic regions. Intermittent preventive …
Article scientifique
Spatiotemporal analysis of Plasmodium falciparum erythrocyte binding antigen-175 gene dimorphism in Ghana
Abstract Background Malaria remains a leading cause of death worldwide, claiming over 600,000 lives each year. Over 90% of these …
Article scientifique
Understanding malaria treatment patronage from informal healthcare providers in Nigerian urban settlements: insights from community members and providers
BACKGROUND: Informal Healthcare Providers (IHCPs), including Proprietary Patent Medicine Vendors (PPMVs), drug peddlers, traditional healers, and herbal drug sellers are …
Article scientifique
Predictors of insecticide-treated nets utilization among children under five years in refugee settlements in Uganda: analysis of the 2018–2019 Uganda Malaria Indicator Survey
BACKGROUND: Despite significant distribution of insecticide-treated net (ITNs) by the Government of Uganda to refugees, malaria is major cause of …
Article scientifique
Semi-field experiments reveal contrasted predation and movement patterns of aquatic macroinvertebrate predators of Anopheles gambiae larvae
BACKGROUND: Members of the Anopheles gambiae complex are major malaria vectors in sub-Saharan Africa. Their larval stages inhabit a variety …
Article scientifique
Genetic diversity of Plasmodium falciparum reticulocyte binding protein homologue-5, which is a potential malaria vaccine candidate: baseline data from areas of varying malaria endemicity in Mainland Tanzania
Abstract Background The limited efficacy of the two recently approved malaria vaccines, RTS,S/AS01 and R21/Matrix- M™, highlights the need for …
Article scientifique
Increasing the resolution of malaria early warning systems for use by local health actors
BACKGROUND: The increasing availability of electronic health system data and remotely-sensed environmental variables has led to the emergence of statistical …