30 publication(s) trouvée(s)
Article scientifique
MVA-BN monkeypox vaccine safety in a clinical trial in the Democratic Republic of the Congo
The MVA-BN vaccine is considered safe and effective and has been widely deployed to prevent monkeypox. However, safety and tolerability …
Article scientifique
Rural-urban differences in oral typhoid vaccine responses in Uganda: contribution of Schistosoma mansoni
Vaccine immunogenicity varies across populations, yet drivers remain unclear. We compared systemic (plasma) and mucosal (coprological) antibody responses to the …
Article scientifique
Pooled analysis of PCV13 efficacy from controlled human infection trials in Malawi and the UK
We conducted the first pooled analysis of two randomised controlled vaccine trials on experimental pneumococcal serotype 6B carriage, registered in …
Article scientifique
Plasmablast, memory B cell and T follicular helper cell responses after human papillomavirus vaccination: effect of dose number and age
Multiple doses of HPV vaccines induce durable, antibody-mediated protection against HPV infections and HPV-associated diseases. Although actual protection against disease …
Article scientifique
Field vaccination against CCHFV and Hyalomma tick infestation reduces multiple tick-borne infections in sheep
Tick-borne pathogens (TBPs) are expanding globally, with their impact on public health expected to rise due to climate change. Immunizing …
Article scientifique
Immunogenicity of one and two doses of Gardasil®9 in Tanzanian girls in the DoRIS Trial
Tanzanian girls received one to three doses of Gardasil®9 in the DoRIS randomised trial. Blood samples from one and two-dose …
Article scientifique
A system to rapidly develop a bunyavirus pseudotyped virus neutralisation assay for pandemic preparedness
Several Bunyavirales families have been listed as being of high pandemic or epidemic risk by the WHO R&D Blueprint. To …
Article scientifique
An antigen panel to assess the regional relevance of foot and mouth disease vaccines
Despite widespread use of inactivated vaccines to control foot-and-mouth disease (FMD), there is no systematic approach to demonstrate the regional …
Article scientifique
PfRH5 vaccine; from the bench to the vial
The search for potent malaria vaccine candidate has seen several twists and turns. Here, we provide a perspective on the …
Article scientifique
Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity against Burkholderia cenocepacia infection in mice
Burkholderia cenocepacia causes life-threatening infections in immunocompromised patients. Treatment is challenging due to intrinsic antibiotic multiresistance, so vaccination provides an …
Article scientifique
The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E
Abstract The recently deployed RTS,S/AS01 E malaria vaccine induces a strong antibody response to the circumsporozoite protein (CSP) on the …
Article scientifique
Impact of rotavirus vaccination in Malawi from 2012 to 2022 compared to model predictions
Rotarix® vaccine was introduced into the Malawi national immunization program in October 2012. We analyzed data on children <5 years …
Article scientifique
Interventions for the control of Crimean-Congo hemorrhagic fever and tick vectors
Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic disease associated with its principal tick vector, Hyalomma spp. with increasing fatal incidence …
Article scientifique
Realising the potential of correlates of protection for vaccine development, licensure and use: short summary
Vaccines have had a significant impact on global morbidity and mortality over the last century, with estimates indicating that millions …
Article scientifique
Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials
Ebola virus disease (EVD) is a filoviral infection caused by virus species of the Ebolavirus genus including Zaire ebolavirus (EBOV) …
Article scientifique
Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells
Neutralizing antibodies strongly correlate with protection for COVID-19 vaccines, but the corresponding memory B cells that form to protect against …
Article scientifique
Systematic review and meta-analysis of myocarditis and pericarditis in adolescents following COVID-19 BNT162b2 vaccination
Myocarditis and pericarditis are frequent complications of COVID-19, but have also been reported following vaccination against COVID-19 in adolescents. To …
Article scientifique
Feasibility of novel adult tuberculosis vaccination in South Africa: a cost-effectiveness and budget impact analysis
Abstract Early trials of novel vaccines against tuberculosis (TB) in adults have suggested substantial protection against TB. However, little is …
Article scientifique
Yellow fever resurgence: An avoidable crisis?
Yellow fever (YF), an acute viral hemorrhagic disease transmitted by infected mosquitoes, has the potential to spread rapidly and cause …
Article scientifique
Author Correction: Antibody responses to the RTS,S/AS01E vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique
In the original version of this Article, the Data Availability statement was missing the link to the datasets generated during …
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