219 publication(s) trouvée(s)
Article scientifique
Violence prevention accelerators for children and adolescents in South Africa: A path analysis using two pooled cohorts
BACKGROUND: The INSPIRE framework was developed by 10 global agencies as the first global package for preventing and responding to …
Article scientifique
Evaluation of an unconditional cash transfer program targeting children’s first-1,000–days linear growth in rural Togo: A cluster-randomized controlled trial
BACKGROUND: In 2014, the government of Togo implemented a pilot unconditional cash transfer (UCT) program in rural villages that aimed …
Article scientifique
The impact of continuous quality improvement on coverage of antenatal HIV care tests in rural South Africa: Results of a stepped-wedge cluster-randomised controlled implementation trial
BACKGROUND: Evidence for the effectiveness of continuous quality improvement (CQI) in resource-poor settings is very limited. We aimed to establish …
Article scientifique
Predictive value of pulse oximetry for mortality in infants and children presenting to primary care with clinical pneumonia in rural Malawi: A data linkage study
BACKGROUND: The mortality impact of pulse oximetry use during infant and childhood pneumonia management at the primary healthcare level in …
Article scientifique
The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis
BACKGROUND: Delay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria …
Article scientifique
Priorities in reducing child mortality: Azithromycin and other interventions
According to World Health Organization (WHO) estimates, the global under-5 mortality rate decreased by 59% between 1990 and 2018, from …
Article scientifique
Biannual azithromycin distribution and child mortality among malnourished children: A subgroup analysis of the MORDOR cluster-randomized trial in Niger
BACKGROUND: Biannual azithromycin distribution has been shown to reduce child mortality as well as increase antimicrobial resistance. Targeting distributions to …
Article scientifique
Providing TB and HIV outreach services to internally displaced populations in Northeast Nigeria: Results of a controlled intervention study
BACKGROUND: A decade of Boko Haram insurgency brought conflict, mass displacement, and the destruction of basic infrastructure to Northeast Nigeria. …
Article scientifique
A new approach to an old problem: Overview of the East African Community’s Medicines Regulatory Harmonization initiative
Substandard and/or falsified medical products may result in treatment failure and/or death.• The capacity to regulate medical products is key …
Article scientifique
An intimate partner violence prevention intervention for men, women, and couples in Ethiopia: Additional findings on substance use and depressive symptoms from a cluster-randomized controlled trial
BACKGROUND: Intimate partner violence (IPV) is linked to substance use by male perpetrators and is associated with an increased risk …
Article scientifique
Coming together to improve access to medicines: The genesis of the East African Community’s Medicines Regulatory Harmonization initiative
points• Independent, science-based regulation of medical products is a critical part of ensuring quality healthcare.When conducted in a transparent, science-based, …
Article scientifique
Optimizing the East African Community’s Medicines Regulatory Harmonization initiative in 2020–2022: A Roadmap for the Future
The East African Community (EAC)'s Medicines Regulatory Harmonization (MRH) initiative was created to improve access to quality, safe medicines in …
Article scientifique
A clinical algorithm for same-day HIV treatment initiation in settings with high TB symptom prevalence in South Africa: The SLATE II individually randomized clinical trial
BACKGROUND: Many countries encourage same-day initiation of antiretroviral therapy (ART), but evidence on eligibility for same-day initiation, how best to …
Article scientifique
Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: Secondary analysis of a household-randomised, placebo-controlled trial in Houndé District, Burkina Faso and Bougouni District, Mali
BACKGROUND: Seasonal malaria chemoprevention (SMC) is now widely deployed in the Sahel, including several countries that are major contributors to …
Article scientifique
Effectiveness of a culturally appropriate intervention to prevent intimate partner violence and HIV transmission among men, women, and couples in rural Ethiopia: Findings from a cluster-randomized controlled trial
BACKGROUND: Intimate partner violence (IPV) is associated with increased HIV risk and other adverse health and psychosocial outcomes. We assessed …
Article scientifique
A multiphase program for malaria elimination in southern Mozambique (the Magude project): A before-after study
BACKGROUND: Malaria eradication remains the long-term vision of the World Health Organization (WHO). However, whether malaria elimination is feasible in …
Erratum
Correction: National and regional prevalence of posttraumatic stress disorder in sub-Saharan Africa: A systematic review and meta-analysis
[This corrects the article DOI: 10.1371/journal.pmed.1003090.].
Article scientifique
The global burden of disease attributable to high body mass index in 195 countries and territories, 1990–2017: An analysis of the Global Burden of Disease Study
BACKGROUND: Obesity represents an urgent problem that needs to be properly addressed, especially among children. Public and global health policy- …
Article scientifique
Safety and continued use of the levonorgestrel intrauterine system as compared with the copper intrauterine device among women living with HIV in South Africa: A randomized controlled trial
BACKGROUND: Women living with HIV (WLHIV) have lower rates of contraceptive use than noninfected peers, yet concerns regarding contraceptive efficacy …
Article scientifique
Mortality estimates by age and sex among persons living with HIV after ART initiation in Zambia using electronic medical records supplemented with tracing a sample of lost patients: A cohort study
BACKGROUND: Men in sub-Saharan Africa have lower engagement and retention in HIV services compared to women, which may result in …