219 publication(s) trouvée(s)
Article scientifique
Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: A meta-analysis of individual in- and outpatient data
BACKGROUND: Tuberculosis (TB) is the most common cause of death in people living with HIV (PLHIV), yet TB often goes …
Article scientifique
National and regional prevalence of posttraumatic stress disorder in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: People living in sub-Saharan Africa (SSA) are disproportionately exposed to trauma and may be at increased risk for posttraumatic …
Article scientifique
HIV testing and treatment coverage achieved after 4 years across 14 urban and peri-urban communities in Zambia and South Africa: An analysis of findings from the HPTN 071 (PopART) trial
BACKGROUND: In 2014, the Joint United Nations Programme on HIV/AIDS (UNAIDS) set the 90-90-90 targets: that 90% of people living …
Article scientifique
Effectiveness of the Common Elements Treatment Approach (CETA) in reducing intimate partner violence and hazardous alcohol use in Zambia (VATU): A randomized controlled trial
BACKGROUND: Both intimate partner violence (IPV) and alcohol misuse are highly prevalent, and partner alcohol misuse is a significant contributor …
Article scientifique
Migration and first-year maternal mortality among HIV-positive postpartum women: A population-based longitudinal study in rural South Africa
BACKGROUND: In South Africa, within-country migration is common. Mobility affects many of the factors in the pathway for entry to …
Article scientifique
Safety and immune responses after a 12-month booster in healthy HIV-uninfected adults in HVTN 100 in South Africa: A randomized double-blind placebo-controlled trial of ALVAC-HIV (vCP2438) and bivalent subtype C gp120/MF59 vaccines
BACKGROUND: HVTN 100 evaluated the safety and immunogenicity of an HIV subtype C pox-protein vaccine regimen, investigating a 12-month booster …
Article scientifique
Virological suppression and clinical management in response to viremia in South African HIV treatment program: A multicenter cohort study
BACKGROUND: Uptake of antiretroviral treatment (ART) is expanding rapidly in low- and middle-income countries (LMIC). Monitoring of virological suppression is …
Article scientifique
Variability in the use of pulse oximeters with children in Kenyan hospitals: A mixed-methods analysis
BACKGROUND: Pulse oximetry, a relatively inexpensive technology, has the potential to improve health outcomes by reducing incorrect diagnoses and supporting …
Article scientifique
The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials
Points• Adherence to prescribed treatment remains a critical component of clinical trials in tuberculosis (TB) treatment.Recent evidence indicates that adherence …
Article scientifique
Addressing the context and consequences of substance use, misuse, and dependence: A global imperative
Substance use, misuse, and dependence contribute immensely to the global burden of disease [1].Their harms extend far beyond their corrosive …
Article scientifique
Advances in clinical trial design for development of new TB treatments—Translating international tuberculosis treatment guidelines into national strategic plans: Experiences from Belarus, South Africa, and Vietnam
The World Health Organization (WHO) plays an important role in setting global norms and standards with a focus on public …
Article scientifique
High quality health systems in the SDG era: Country-specific priorities for improving quality of care
Long a concern in high-income countries, health system quality emerged as a truly global priority in 2018.Three major reports [1-3] …
Article scientifique
Text messaging for maternal and infant retention in prevention of mother-to-child HIV transmission services: A pragmatic stepped-wedge cluster-randomized trial in Kenya
BACKGROUND: Timely diagnosis of infant HIV infection is essential for antiretroviral therapy (ART) initiation. In a randomized controlled trial, we …
Article scientifique
Maternal exposure to intimate partner violence and breastfeeding practices in 51 low-income and middle-income countries: A population-based cross-sectional study
BACKGROUND: Intimate partner violence (IPV) against women is a major global health issue, particularly in low- and middle-income countries (LMICs), …
Article scientifique
Redesigning care for older people to preserve physical and mental capacity: WHO guidelines on community-level interventions in integrated care
points• Numerous underlying physiological changes occur with increasing age, and for older people, the risks of developing chronic diseases and …
Article scientifique
Progression to type 2 diabetes mellitus and associated risk factors after hyperglycemia first detected in pregnancy: A cross-sectional study in Cape Town, South Africa
BACKGROUND: Global data indicate that women with a history of hyperglycemia first detected in pregnancy (HFDP) are at up to …
Article scientifique
Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study)
BACKGROUND: The global transition to use of dolutegravir (DTG) in WHO-preferred regimens for HIV treatment is limited by lack of …
Article scientifique
Integrating preexposure prophylaxis delivery in routine family planning clinics: A feasibility programmatic evaluation in Kenya
BACKGROUND: Young women account for a disproportionate fraction of new HIV infections in Africa and are a priority population for …
Article scientifique
Nutrition for women and children—Are we doing the right things in the right way?
The recent 2019 report on the State of Food Security and Nutrition in the World paints a picture of some …
Article scientifique
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia
BACKGROUND: Infant DNA methylation profiles are associated with their mother's periconceptional nutritional status. DNA methylation relies on nutritional inputs for …