210 publication(s) trouvée(s)
Article scientifique
Surveillance of respiratory viruses among children attending a primary school in rural coastal Kenya
Background: Respiratory viruses are primary agents of respiratory tract diseases. Knowledge on the types and frequency of respiratory viruses affecting …
Article scientifique
Effectiveness of Rotarix® vaccine in Africa in the first decade of progressive introduction, 2009-2019: systematic review and meta-analysis
Background: Randomized controlled trials of licensed oral rotavirus group A (RVA) vaccines, indicated lower efficacy in developing countries compared to …
Article scientifique
Role of a regulatory and governance framework in human biological materials and data sharing in National Biobanks: Case studies from Biobank Integrating Platform, Taiwan and the National Biorepository, Uganda
Background: In the last decade, Low- and Middle-Income Countries (LMICs) have set up Biobanks to collect human biological materials and …
Article scientifique
Acceptability and feasibility of genital self-sampling for the diagnosis of female genital schistosomiasis: a cross-sectional study in Zambia
Background : Female genital schistosomiasis (FGS) is a neglected and disabling gynaecological disorder that is difficult to diagnose and is …
Article scientifique
Fitness cost of insecticide resistance on the life-traits of a Anopheles coluzzii population from the city of Yaoundé, Cameroon
Background: Pyrethroid resistance is rapidly expanding in An. gambiae s.l. populations across Sub-Saharan Africa. Yet there is still not enough …
Article scientifique
Impact of Plasmodium falciparum small-sized extracellular vesicles on host peripheral blood mononuclear cells
Background: Exagerated immune activation has a key role in the pathogenesis of malaria . During blood-stage infection, Plasmodium falciparum can …
Article scientifique
Entomological indicators of malaria transmission and insecticide resistance profile of Anopheles gambiae at the early phase of irrigated rice farming in the forest area of central Cameroon
Background: Cameroonian authorities have recently established irrigated rice projects across the country. The assessment of the impact of such projects …
Article scientifique
Contrasting impact of rural, versus urban, living on glucose metabolism and blood pressure in Uganda
Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been …
Article scientifique
High dose oral rifampicin to improve survival from adult tuberculous meningitis: A randomised placebo-controlled double-blinded phase III trial (the HARVEST study)
Background: Tuberculous meningitis (TBM), the most severe form of tuberculosis (TB), results in death or neurological disability in >50%, despite …
Article scientifique
Accuracy of diagnostic tests for respiratory syncytial virus infection within a paediatric hospital population in Kilifi County, Kenya
Background: Respiratory syncytial virus (RSV)-induced lower respiratory tract disease is a prominent cause of hospitalisation among children aged <5 years …
Article scientifique
Characterising demographics, knowledge, practices and clinical care among patients attending sickle cell disease clinics in Eastern Uganda
Background : In Uganda to date, there are neither established registries nor descriptions of facility-based sickle cell disease (SCD) patient …
Article scientifique
Estimating the burden of antimicrobial resistance in Malawi: protocol for a prospective observational study of the morbidity, mortality and economic cost of third-generation cephalosporin resistant bloodstream infection
Introduction: Antimicrobial resistance (AMR) is a global public health concern, but the problems are context specific, with each county or …
Article scientifique
Effects of vitamin D deficiency on neurobehavioural outcomes in children: a systematic review
Introduction: Vitamin D plays an important role in brain development in experimental studies; however, the effect of vitamin D deficiency …
Article scientifique
Elevated Plasmodium sporozoite infection and multiple insecticide resistance in the principal malaria vectors Anopheles funestus and Anopheles gambiae in a forested locality close to the Yaoundé airport, Cameroon
Background: Reducing the burden of malaria requires better understanding of vector populations, particularly in forested regions where the incidence remains …
Article scientifique
Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes
Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely to monitor endemic …
Article scientifique
A pneumococcal controlled human infection model in Malawi: Transfer of an established pneumococcal carriage model from Liverpool, UK to Blantyre, Malawi – A feasibility study
Streptococcus pneumoniae is the leading cause of morbidity and mortality due to community acquired pneumonia, bacterial meningitis and bacteraemia worldwide. …
Article scientifique
Patterns of neurobehavioral functioning in school-aged survivors of neonatal jaundice and hypoxic-ischemic encephalopathy in Kilifi, Kenya: A cross-sectional study
Background: Studies in high-income countries have reported that school-aged children who survive neonatal jaundice (NNJ) and hypoxic-ischemic encephalopathy (HIE) develop …
Article scientifique
Case Report: Furuncular Myiasis in Malawi
Furuncular myiasis results when the larva penetrates healthy skin to cause a furuncle like nodule which may mimic common dermatoses …
Article scientifique
Cost-effectiveness of reflex laboratory-based cryptococcal antigen screening for the prevention and treatment of cryptococcal meningitis in Botswana
Background: Cryptococcal antigen (CrAg) screening for antiretroviral therapy (ART)-naïve adults with advanced HIV/AIDS can reduce the incidence of cryptococcal meningitis …
Article scientifique
A protocol for an observational cohort study of heat strain and its effect on fetal wellbeing in pregnant farmers in The Gambia
Introduction: Climate change predictions indicate that global temperatures are likely to exceed those seen in the last 200,000 years, rising …