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Publications
7352 publication(s) trouvée(s)
Article scientifique
Exploring genetic diversity and variation of Ovar-DRB1 gene in Sudan Desert Sheep using targeted next-generation sequencing
Abstract Introduction The Ovar-DRB1 gene, a crucial element of the Major Histocompatibility Complex (MHC) Class II region, initiates adaptive immunity …
Article scientifique
Molecular analysis of multidrug-resistant E. coli in pediatric UTIs: findings from a Nigerian Hospital
INTRODUCTION: This study aimed to isolate and characterize antibiotic-resistant Escherichia coli from urine samples of children at the Mother and …
Article scientifique
Trichuris trichiura infection is associated with changes in gut microbiome composition and function among women of reproductive age from Pemba, Tanzania
Large intestine-dwelling helminths affect microbiome composition. In sub-Saharan Africa, where helminth infections are endemic, the use of chemotherapeutic drugs is …
Article scientifique
Diversity of selected toll-like receptor genes in cheetahs (Acinonyx jubatus) and African leopards (Panthera pardus pardus)
The anthropogenic impact on wildlife is ever increasing. With shrinking habitats, wild populations are being pushed to co-exist in proximity …
Article scientifique
Machine learning and bioinformatic analyses link the cell surface receptor transcript levels to the drug response of breast cancer cells and drug off-target effects
Breast cancer responds variably to anticancer therapies, often leading to significant off-target effects. This study proposes that the variability in …
Article scientifique
Altered expression of serum lncRNA CASC2 and miRNA-21-5p in COVID-19 patients
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has a high incidence of …
Article scientifique
Non-toxigenic Corynebacterium diphtheriae endocarditis: A cluster of five cases
Background: Classical toxin-mediated respiratory diphtheria has become less common because of widespread effective vaccination globally but invasive disease as a …
Article scientifique
The neuroprotective potential of curcumin on T. Spiralis infected mice
BACKGROUND: Trichinella spiralis can affect the brain by inducing inflammatory and vascular changes. Drug management with the antiparasitic drug albendazole …
Article scientifique
Perceptions and beliefs of community gatekeepers about genomic risk information in African cleft research
BACKGROUND: A fundamental ethical issue in African genomics research is how socio-cultural factors impact perspectives, acceptance, and utility of genomic …
Article scientifique
Analyzing the Nutritional Awareness, Dietary Practices, Attitudes, and Performance of U-17 Football Players in Ethiopia
Background. Adequate nutrition knowledge is crucial for developing proper eating habits, especially among athletes, as it has a significant impact …
Article scientifique
Mapping pathogenic bacteria resistance against common antibiotics and their potential susceptibility to methylated white kidney bean protein
As antibiotics cannot inhibit multidrug-resistant bacteria (MDR), continuous research is mandatory to find other antibacterials from natural resources. Native legume …
Article scientifique
Epigenetic aging in older people living with HIV in Eswatini: a pilot study of HIV and lifestyle factors and epigenetic aging
Abstract Background People living with HIV (PLHIV) on effective antiretroviral therapy are living near-normal lives. Although they are less susceptible …
Article scientifique
Cytotoxic metabolites from Sinularia levi supported by network pharmacology
The in-vitro anti-proliferative evaluation of Sinularia levi total extract against three cell lines revealed its potent effect against Caco-2 cell …
Article scientifique
Detection and quantitative microbial risk assessment of pathogenic Vibrio cholerae in a river used for drinking, domestic, fresh produce irrigation and recreational purposes
Abstract Cholera infection results from the ingestion of water or food contaminated with toxigenic Vibrio cholerae. This study evaluated the …
Article scientifique
Effect of Radiotherapy on Activating the Pyroptotic Cell Death Pathway in Breast Cancer Patients: The Role of Serum GSDMD-CT, NLRP3 and IL-18
BACKGROUND: Breast cancer (BC) is the most common form of cancer among women and the second leading cause of cancer-related …
Article scientifique
Comparative analysis of breast cancer characteristics in young premenopausal and postmenopausal women in Ghana
Breast cancer is increasingly common among young women in Ghana. BCa is heterogeneous with unique traits that impact causes, prognostic, …
Article scientifique
Effect of pineapple waste biochar and compost application on the growth and yield of pineapple varieties in Ghana
Introduction Biochar is one of the commonly used soil amendments for sustainable agriculture. The effect of biochar on crop yields …
Article scientifique
Combatting anthrax outbreaks across Nigeria’s national land borders: need to optimize surveillance with epidemiological surveys
BACKGROUND: Anthrax is a non-contagious zoonotic disease caused by the Gram-positive, spore-forming bacterium Bacillus anthracis. Infection is common in livestock …
Article scientifique
Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniae
BACKGROUND: Carbapenems represent the first line treatment of serious infections caused by drug-resistant Klebsiella pneumoniae. Carbapenem-resistant K. pneumoniae (CRKP) is …
Article scientifique
Prevalence of phenotypic multi-drug resistant Klebsiella species recovered from different human specimens in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Multidrug-resistant (MDR) Klebsiella species are among public health important bacteria that cause infections difficult to treat with available antimicrobial …