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Publications
7352 publication(s) trouvée(s)
Article scientifique
Production and characterization of melanin pigment from black fungus Curvularia soli AS21 ON076460 assisted gamma rays for promising medical uses
Abstract Owing to the growing need for natural materials in different fields, studying melanin production from biological sources is imperative. …
Article scientifique
HIV-associated gut microbial alterations are dependent on host and geographic context
HIV-associated changes in intestinal microbiota are believed to be important drivers of disease progression. However, the majority of studies have …
Article scientifique
Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors
Abstract A receptor-based pharmacophore model describing the binding features required for the multi-kinase inhibition of the target kinases (VEGFR-2, FGFR-1, …
Article scientifique
Meat and meat products as potential sources of emerging MDR Bacillus cereus: groEL gene sequencing, toxigenic and antimicrobial resistance
BACKGROUND: Bacillus cereus is implicated in severe foodborne infection in humans. This study intended to assess the occurrence, groEL gene …
Article scientifique
Correlation between antimicrobial resistance, biofilm formation, and virulence determinants in uropathogenic Escherichia coli from Egyptian hospital
BACKGROUND: Uropathogenic Escherichia coli (UPEC) is the main etiological agent behind community-acquired and hospital-acquired urinary tract infections (UTIs), which are …
Article scientifique
Immunoinformatics, molecular docking and dynamics simulation approaches unveil a multi epitope-based potent peptide vaccine candidate against avian leukosis virus
Lymphoid leukosis is a poultry neoplastic disease caused by avian leukosis virus (ALV) and is characterized by high morbidity and …
Article scientifique
The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target
Cancer chemoresistance is a problematic dilemma that significantly restrains numerous cancer management protocols. It can promote cancer recurrence, spreading of …
Article scientifique
Gut microbiota-gonadal axis: the impact of gut microbiota on reproductive functions
The influence of gut microbiota on physiological processes is rapidly gaining attention globally. Despite being under-studied, there are available data …
Article scientifique
Fibroblast growth factor-21 and Visfatin as potential predictors for metabolic risk factors in obese children
Fibroblast growth factor-21 (FGF-21) and Visfatin are associated with obesity. However; reviewing the literature; no studies were found to assess …
Article scientifique
Community engagement in genetics and genomics research: a qualitative study of the perspectives of genetics and genomics researchers in Uganda
BACKGROUND: Generally, there is unanimity about the value of community engagement in health-related research. There is also a growing tendency …
Article scientifique
Characterization and biological applications of gonadal extract of Paracentrotus lividus collected along the Mediterranean coast of Alexandria, Egypt
Marine invertebrates represent a valuable reservoir of pharmaceutical bioactive compounds with potential relevance to various medical applications. These compounds exhibit …
Article scientifique
Genomic characterization of Listeria monocytogenes and Listeria innocua isolated from milk and dairy samples in Ethiopia
Listeriosis caused by Listeria monocytogenes often poses a significant threat to vulnerable populations. Dairy products have been implicated in outbreaks …
Article scientifique
Characterization, modeling, and anticancer activity of L.arginase production from marine Bacillus licheniformis OF2
BACKGROUND: L-arginase, is a powerful anticancer that hydrolyzes L-arginine to L-ornithine and urea. This enzyme is widely distributed and expressed …
Article scientifique
Dissemination of mcr-1 and β-lactamase genes among Pseudomonas aeruginosa: molecular characterization of MDR strains in broiler chicks and dead-in-shell chicks infections
OBJECTIVES: Pseudomonas aeruginosa (P. aeruginosa) is one of the most serious pathogens implicated in antimicrobial resistance, and it has been …
Article scientifique
Aspergillus-Penicillium co-culture: An investigation of bioagents for controlling Fusarium proliferatum-induced basal rot in onion
Fungal co-culture is a method that allows the detection of interactions between fungi, enabling the examination of bioactive novel metabolites …
Article scientifique
Influence of copper(I) nicotinate complex on the Notch1 signaling pathway in triple negative breast cancer cell lines
Abstract Triple negative breast cancer (TNBC) is a subtype of breast cancer which is characterized by its aggressiveness, poor and …
Article scientifique
Toxicological analyses of the venoms of Nigerian vipers Echis ocellatus and Bitis arietans
Abstract Background Among the medically important snakes in Nigeria, Echis ocellatus and Bitis arietans have the most lethal venom. These …
Article scientifique
Molecular characterization of an outbreak-involved Bacillus anthracis strain confirms the spillover of anthrax from West Africa
BACKGROUND: Anthrax, a zoonotic disease caused by the spore-forming bacterium Bacillus anthracis, remains a major global public health concern, especially …
Article scientifique
Melatonin enhances captopril mediated cardioprotective effects and improves mitochondrial dynamics in male Wistar rats with chronic heart failure
Mitochondrial dysfunction is a recent emerging research scope that proved to be involved in many cardiovascular diseases culminating in chronic …
Article scientifique
SIRT1 as a potential key regulator for mediating apoptosis in oropharyngeal cancer using cyclophosphamide and all-trans retinoic acid
Although cyclophosphamide (CTX) has been used for recurrent or metastatic head and neck cancers, resistance is usually expected. Thus, we …