7348
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Biologie synthétique
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Publications
7348 publication(s) trouvée(s)
Article scientifique
Experimental and hypothetical appraisal on inhibition of glucose-induced glycation of bovine serum albumin by quercetin
BACKGROUND: The specificity of protein functions depends on its folding ability into a functional structure. Protein folding is an essential …
Article scientifique
First records of Clubiona hitchinsi Saaristo, 2002 on Ascension Island (Araneae, Clubionidae)
Clubiona hitchinsi Saaristo, 2002, previously known from the Seychelles and French Polynesia, is newly recorded from Ascension Island, based on …
Article scientifique
Molecular Detection of Key Virulence-associated Genes and Phenotypic Analysis of Virulence Traits of Klebsiella pneumoniae Clinical Isolates from Kenya
Klebsiella pneumoniae is an opportunistic pathogen and a major cause of nosocomial infections. Phenotypic analysis of virulence and molecular typing …
Article scientifique
Socioecological systems analysis of potential factors for cholera outbreaks and assessment of health system’s readiness to detect and respond in Ilemela and Nkasi districts, Tanzania
BACKGROUND: Cholera outbreaks are a recurrent issue in Tanzania, with Ilemela and Nkasi districts being particulary affected. The objective of …
Article scientifique
Tazemetostat decreases β-catenin and CD13 protein expression in HEPG-2 and Hepatitis B virus-transfected HEPG-2 with decreased cell viability
Hepatocellular carcinoma (HCC) is one of the global health concerns. Hepatitis B virus (HBV) is one of the major causes …
Article scientifique
Immunohistochemistry-derived subtypes of breast cancer distribution in four regions of Ethiopia
Purpose: Different biological characteristics, therapeutic responses, and disease-specific outcomes are associated with different molecular subtypes of breast cancer (BC). Although …
Article scientifique
Anti-proliferative activity of RIHMS-Qi-23 against MCF-7 breast cancer cell line is through inhibition of cell proliferation and senescence but not inhibition of targeted kinases
BACKGROUND: Breast cancer is the most common malignancy globally, and is considered a major cause of cancer-related death. Tremendous effort …
Article scientifique
In silico SNP prediction of selected protein orthologues in insect models for Alzheimer's, Parkinson's, and Huntington’s diseases
Alzheimer's, Parkinson's, and Huntington's are the most common neurodegenerative diseases that are incurable and affect the elderly population. Discovery of …
Article scientifique
Albendazole-induced genotoxicity in the larvae of fall armyworm as a safe environmental tool
Abstract Anthelmintic drugs are considered a new alternative strategy to control insect pests. Spodoptera frugiperda, fall armyworm (FAW), is one …
Article scientifique
Immune activation and inflammation in lactating women on combination antiretroviral therapy: role of gut dysfunction and gut microbiota imbalance
Introduction Combination antiretroviral therapy (cART) effectively controls HIV; however, chronic low-level viremia and gut microbiota dysbiosis remain significant drivers of …
Article scientifique
Colistin Resistance among Enterobacterales Isolates: Underlying Mechanisms and Alternative Treatment Options
Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving …
Article scientifique
Small heat shock proteins as modulators of cell death in Plasmodium falciparum parasites and its human host
Plasmodium falciparum, the predominant cause of severe malaria, thrives within both poikilotherm mosquitoes and homeotherm humans, navigating challenging temperature shifts …
Article scientifique
Genome-wide association studies on coronary artery disease: A systematic review and implications for populations of different ancestries
BACKGROUND: Cardiovascular diseases are some of the leading causes of death worldwide, with coronary artery disease leading as one of …
Article scientifique
Non-fermenter Gram-negative bacilli at a tertiary hospital, South Africa
Background: Non-fermenting Gram-negative bacilli (NFGNB) are a significant cause of healthcare-associated infections and are often implicated in nosocomial outbreaks. Non- …
Article scientifique
Pregnancy and diabetic ketoacidosis: fetal jeopardy and windows of opportunity
Background: Diabetic ketoacidosis (DKA) during pregnancy poses significant risks to both the mother and fetus, with an increased risk of …
Article scientifique
Unmasking the invaders: NLR-mal function in plant defense
gene clusters have recently gained momentum owing to their robustness and malleability in adapting to recognize pathogens. The modular domain …
Article scientifique
The human genome as the common heritage of humanity
While debate on the international regulation of human genomic research remains unsettled, the Universal Declaration on the Human Genome and …
Article scientifique
Risk factors for diarrheagenic Escherichia coli infection in children aged 6–24 months in peri-urban community, Nairobi, Kenya
Escherichia coli commonly inhabits the gut of humans and animals as part of their microbiota. Though mostly innocuous, some strains …
Article scientifique
“I sold my towel and shoes to pay the traditional healer”: Care-seeking costs and productivity losses among snakebite victims in Eastern Province, Rwanda
Snakebite envenomation (SBE) is endemic to sub-Saharan Africa and generally over-represented in rural, remote, and impoverished agricultural communities. While poverty …
Article scientifique
Perceptions of Nigerian medical students regarding their preparedness for precision medicine: a cross-sectional survey in Lagos, Nigeria
Abstract Background Advances in precision medicine in Nigeria suggest improving genomics education and competency among healthcare practitioners to facilitate clinical …