7342
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Biologie synthétique
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Publications
7342 publication(s) trouvée(s)
Article scientifique
Bioactivities of Garcinia kola enzymatic hydrolysates at different enzyme–substrate ratios
Abstract Natural products, such as enzymatic hydrolysates and bioactive peptides from dietary sources, are safe alternatives to synthetic compounds linked …
Article scientifique
Resourcefulness of propylprodigiosin isolated from Brevundimonas olei strain RUN-D1
Abstract A novel red-pigmented bacterium was isolated from a water sample collected at Osun River, Ede. Morphological and 16 S …
Article scientifique
Impact of Plasmodium falciparum infection on DNA methylation of circulating immune cells
The regulation of immune cell responses to infection is a complex process that involves various molecular mechanisms, including epigenetic regulation. …
Article scientifique
Prognostic Value of Plasma miR-29a Evaluation in Chronic Lymphocytic Leukemia Patients
OBJECTIVE: Dysregulation of microRNA expression could attenuate the course of chronic lymphocytic leukemia (CLL). Therefore, the aim of our study …
Article scientifique
Variation in herbivore space use: comparing two savanna ecosystems with different anthrax outbreak patterns in southern Africa
BACKGROUND: The distribution of resources can affect animal range sizes, which in turn may alter infectious disease dynamics in heterogenous …
Article scientifique
Anandamide modulates WNT-5A/BCL-2, IP3/NFATc1, and HMGB1/NF-κB trajectories to protect against mercuric chloride-induced acute kidney injury
Abstract Endocannabinoid anandamide (AEA) has a physiological role in regulating renal blood flow, whereas its analogs ameliorated renal ischemia/reperfusion injury. …
Article scientifique
Genetic characterization of Escherichia coli and Klebsiella spp. from humans and poultry in Nigeria
The emergence of antibiotic resistance in livestock, especially food-producing animals, is of major public health importance as a result of …
Article scientifique
Potential biomarkers for southern African hunter-gatherer arrow poisons applied to ethno-historical and archaeological samples
The detection of complex poison recipes applied to ancient hunting weapons has the potential to provide important insights into traditional …
Article scientifique
Propranolol restores susceptibility of XDR Gram-negative pathogens to meropenem and Meropenem combination has been evaluated with either tigecycline or amikacin
BACKGROUND: Infection with extensive-drug-resistant (XDR) carbapenem-resistant (CR) Gram-negative bacteria (GNB) are viewed as a serious threat to human health because …
Article scientifique
Community members and healthcare workers’ priorities for the control and prevention of snakebite envenoming in Ghana
INTRODUCTION: Snakebite is one of the most neglected tropical diseases. In Ghana, there has been a limited interest in snakebite …
Article scientifique
Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents
Abstract An optimization strategy was adopted for designing and synthesizing new series of 2-oxindole conjugates. Selected compounds were evaluated for …
Article scientifique
Molecular modeling study of micro and nanocurcumin with in vitro and in vivo antibacterial validation
Repurposing natural compounds as inhibitory targets to combat bacterial virulence is an important potential strategy to overcome resistance to traditional …
Article scientifique
RNA-seq research landscape in Africa: systematic review reveals disparities and opportunities
RNA sequencing has emerged as the standard method for transcriptome profiling of several human diseases. We performed a systematic review …
Article scientifique
Effect of chemical and biological additives on production of biogas from coffee pulp silage
Energy is the foundation of the global economy and is essential to human survival. Nevertheless, more than 60% of it …
Article scientifique
Isolation and genotypic characterization of extended-spectrum beta-lactamase-producing Escherichia coli O157:H7 and Aeromonas hydrophila from selected freshwater sources in Southwest Nigeria
Abstract The proliferation of antibiotic-resistant bacteria and antimicrobial resistance is a pressing public health challenge because of their possible transfer …
Article scientifique
Optimization of infectious bronchitis virus-like particle expression in Nicotiana benthamiana as potential poultry vaccines
Infectious bronchitis (IB) is a highly contagious, acute respiratory disease in chickens, with a severe economic impact on poultry production …
Article scientifique
The effect of single dose albendazole (400 mg) treatment on the human gut microbiome of hookworm-infected Ghanaian individuals
Microbes play a key role in human gut homeostasis, metabolic, immunologic and physiopathology of the body. A longitudinal study conducted …
Article scientifique
Araucaria heterophylla oleogum resin essential oil is a novel aldose reductase and butyryl choline esterase enzymes inhibitor: in vitro and in silico evidence
Abstract The essential oil isolated by hydrodistillation of the oleogum resin of Araucaria heterophylla has been analyzed by GC–MS. Twenty-four …
Article scientifique
Compendium of medically important snakes, venom activity and clinical presentations in Ghana
BACKGROUND: Snake bite envenoming (SBE) is one neglected tropical disease that has not received the needed attention. The sequelae of …
Article scientifique
Exploring the antibacterial potential of plant extracts and essential oils against Bacillus thermophilus in beet sugar for enhanced sucrose retention: a comparative assessment and implications
Sugar beet is one of the greatest sources for producing sugar worldwide. However, a group of bacteria grows on beets …