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Publications
7342 publication(s) trouvée(s)
Article scientifique
Therapeutic potential of stem cells and acitretin on inflammatory signaling pathway-associated genes regulated by miRNAs 146a and 155 in AD-like rats
Alzheimer's disease (AD) is one of the most common causes of dementia. Several drugs are used to improve the symptoms, …
Article scientifique
High burden of diabetes and prediabetes among cancer patients at University of Gondar comprehensive specialized hospital, Northwest Ethiopia
Cancer and diabetes mellitus (DM) are diagnosed within the same individual more frequently and share common risk factors. Although diabetes …
Article scientifique
Chemical and Elemental Composition of Ammi visnaga L. and Calendula officinalis L. from Meknes, Morocco
The powders of Ammi visnaga L. and Calendula officinalis L. plants collected from Meknes region were subjected to three types …
Article scientifique
Whole strains vs MGEs in short and longterm transmission of ESBL genes between healthcare and community settings in Uganda
Abstract Multidrug-resistant ESBL-producing Escherichia coli are a leading cause of infections in hospital and community settings. Based on samples from …
Article scientifique
Metastatic breast cancer in Kenya: survival, prognosis and management at a tertiary referral centre
There has been an increase in breast cancer in Africa with up to 77% of patients diagnosed with advanced disease. …
Article scientifique
Allele distribution and phenotypic resistance to ciprofloxacin and gentamicin among extended-spectrum β-lactamase-producing Escherichia coli isolated from the urine, stool, animals, and environments of patients with presumptive urinary tract infection in Tanzania
Background Additional antimicrobial resistance to extended-spectrum β-lactamase (ESBL)-producing E. coli exhausts treatment options. We investigated allele distribution and resistance to …
Article scientifique
Diagnostic characteristics of the 20-minute whole blood clotting test in detecting venom-induced consumptive coagulopathy following carpet viper envenoming
INTRODUCTION: Envenoming by Echis spp. (carpet or saw-scaled vipers) causes haemorrhage and coagulopathy and represents a significant proportion of snakebites …
Article scientifique
Insights into the mechanisms governing P01 scorpion toxin effect against U87 glioblastoma cells oncogenesis
The emerging concept of small conductance Ca 2+ -activated potassium channels (SK Ca ) as pharmacological target for cancer treatment …
Article scientifique
Advancing oncology drug therapies for sub-Saharan Africa
Cancer incidence is rising across sub-Saharan Africa (SSA), and is often characterized by late-stage presentation, early age of onset and …
Article scientifique
Phenotypic Bacterial Isolates, Antimicrobial Susceptibility pattern and Associated factors among Septicemia Suspected Patients at a hospital, in Northwest Ethiopia: Prospective cross-sectional study
BACKGROUND: Septicemia is potentially fatal infection caused by pathogenic bacteria infiltrating the bloodstream, resulting in morbidity and mortality among Ethiopian …
Article scientifique
Cytotoxic flavone-C-glycosides from the leaves of Dypsis pembana (H.E.Moore) Beentje & J.Dransf., Arecaceae: in vitro and molecular docking studies
BACKGROUND: Cancer poses a health threat, with an increased incidence worldwide. Thus, it is essential to develop new natural anticancer …
Article scientifique
Human adenovirus DNA polymerase is evolutionarily and functionally associated with human telomerase reverse transcriptase based on in silico molecular characterization that implicate abacavir and zidovudine
Human adenoviruses (HAdVs) are non-enveloped, small double stranded DNA (dsDNA) viruses that cause asymptomatic infections, clinical syndromes and significant susceptibility …
Article scientifique
Source-tracking ESBL-producing bacteria at the maternity ward of Mulago hospital, Uganda
INTRODUCTION: Escherichia coli, Klebsiella pneumoniae and Enterobacter (EKE) are the leading cause of mortality and morbidity in neonates in Africa. …
Article scientifique
In vitro antiproliferative, anti-inflammatory effects and molecular docking studies of natural compounds isolated from Sarcocephalus pobeguinii (Hua ex Pobég)
Background:Sarcocephalus pobeguinii (Hua ex Pobég) is used in folk medicine to treat oxidative-stress related diseases, thereby warranting the investigation of …
Article scientifique
Cholera outbreak in Syria amid humanitarian crisis: the epidemic threat, future health implications, and response strategy – a review
The war in Syria, which started over 11 years ago, has devastated the country's water sources, healthcare system, and other …
Article scientifique
Multidrug-resistant and extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated from chicken droppings in poultry farms at Gondar City, Northwest Ethiopia
BACKGROUND: The poultry sector is one of the largest and fastest-growing agricultural sub-sector, especially in developing countries like Ethiopia. In …
Article scientifique
Succession and determinants of the early life nasopharyngeal microbiota in a South African birth cohort
BACKGROUND: Bacteria colonizing the nasopharynx play a key role as gatekeepers of respiratory health. Yet, dynamics of early life nasopharyngeal …
Article scientifique
Effect of silver nanoparticles on tropane alkaloid production of transgenic hairy root cultures of Hyoscyamus muticus L. and their antimicrobial activity
The utilization of nanotechnology and biotechnology for enhancing the synthesis of plant bioactive chemicals is becoming increasingly common. The hairy …
Article scientifique
High burden of ESBL and carbapenemase-producing gram-negative bacteria in bloodstream infection patients at a tertiary care hospital in Addis Ababa, Ethiopia
BACKGROUND: Bloodstream infection due to beta-lactamase and carbapenemase-producing gram-negative bacteria poses a substantial challenge to the effectiveness of antimicrobial treatments. …
Article scientifique
Diversity of Cladosporium (Cladosporiales, Cladosporiaceae) species in marine environments and report on five new species
Cladosporium species are cosmopolitan fungi, characterized by olivaceous or dark colonies with coronate conidiogenous loci and conidial hila with a …