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7361 publication(s) trouvée(s)
Article scientifique
Application of transposon systems in the transgenesis of bovine somatic and germ cells
BACKGROUND: Several DNA transposons including PiggyBac (PB), Sleeping Beauty (SB), and Tol2 have been applied as effective means for of …
Article scientifique
Determination of extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolated from horses with respiratory manifestation
Background and Aim: The World Health Organization considers multidrug-resistant (MDR) Klebsiella pneumoniae a major global threat. Horses harbor commensal isolates …
Article scientifique
Gene profiling of SEC13, SMAD7, GHRL, long non-coding RNA GHRLOS, HIF-1α in gastric cancer patients
Even with considerable progress in cancer researches, gastric cancer is still one of the global health problems. Recognition of the …
Article scientifique
Fusarium species isolated from post-hatchling loggerhead sea turtles (Caretta caretta) in South Africa
Species in the Fusarium solani species complex are fast growing, environmental saprophytic fungi. Members of this genus are filamentous fungi …
Article scientifique
The characteristics and perioperative outcomes of children with orofacial clefts managed at an academic hospital in Johannesburg, South Africa
BACKGROUND: Orofacial clefts (OFCs) are the commonest congenital anomalies of the head and neck. Their aetiology is multifactorial, and prevalence …
Article scientifique
Immunoinformatics approach of epitope prediction for SARS-CoV-2
BACKGROUND: The novel coronavirus (SARS-CoV-2) caused lethal infections worldwide during an unprecedented pandemic. Identification of the candidate viral epitopes is …
Article scientifique
Microbiomics: The Next Pillar of Precision Medicine and Its Role in African Healthcare
Limited access to technologies that support early monitoring of disease risk and a poor understanding of the geographically unique biological …
Article scientifique
Coupling genetic structure analysis and ecological-niche modeling in Kersting’s groundnut in West Africa
Orphan legume crops play an important role in smallholder farmers' food systems. Though less documented, they have the potential to …
Article scientifique
A local Talaromyces atroroseus TRP-NRC isolate: isolation, genetic improvement, and biotechnological approach combined with LC/HRESI-MS characterization, skin safety, and wool fabric dyeing ability of the produced red pigment mixture
BACKGROUND: During the last decade, enormous research efforts have been directed at identifying potent microorganisms as sustainable green cell factories …
Article scientifique
Climate change will disproportionally affect the most genetically diverse lineages of a widespread African tree species
Global climate change is proceeding at an alarming rate with major ecological and genetic consequences for biodiversity, particularly in drylands. …
Article scientifique
Characterization, in-silico, and in-vitro study of a new steroid derivative from Ophiocoma dentata as a potential treatment for COVID-19
Abstract The medicinal potential of marine invertebrates' bioactive components that may act as anti-COVID-19 demonstrated promising results. Ophiocoma dentata, which …
Article scientifique
The African Female Breast Cancer Epidemiology Study Protocol
Breast cancer is now the commonest cancer in most sub-Saharan African countries. Few studies of the epidemiology and genomics of …
Article scientifique
(GTG)5-PCR fingerprinting of multi-drug resistant Escherichia coli bacteria isolates from hospital in Ouagadougou, Burkina Faso
Abstract Background Escherichia coli (E. coli) is the most common bacterial species implicated in various types of infections including septicemia, …
Article scientifique
Clinico-Epidemiological Characteristics of Patients With Inflammatory Bowel Disease in Egypt: A Nationwide Multicenter Study
Background and Aims Ulcerative colitis (UC) and Crohn's disease (CD) are the most common types of Inflammatory bowel disease (IBD), …
Article scientifique
PRObiotics and SYNbiotics to improve gut health and growth in infants in western Kenya (PROSYNK Trial): study protocol for a 4-arm, open-label, randomised, controlled trial
BACKGROUND: Malnutrition amongst under-fives remains common in resource-poor countries and is resistant to current interventions. New opportunities have emerged to …
Article scientifique
Genome-wide investigations reveal the population structure and selection signatures of Nigerian cattle adaptation in the sub-Saharan tropics
BACKGROUND: Cattle are considered to be the most desirable livestock by small scale farmers. In Africa, although comprehensive genomic studies …
Article scientifique
How does handwashing behaviour change in response to a cholera outbreak? A qualitative case study in the Democratic Republic of the Congo
BACKGROUND: Handwashing with soap has the potential to curb cholera transmission. This research explores how populations experienced and responded to …
Article scientifique
The predictive potential of different molecular markers linked to amikacin susceptibility phenotypes in Pseudomonas aeruginosa
Informed antibiotic prescription offers a practical solution to antibiotic resistance problem. With the increasing affordability of different sequencing technologies, molecular-based …
Article scientifique
Assessment of risk factors and molecular biomarkers in children with supernumerary teeth: a single-center study
BACKGROUND: Supernumerary teeth are considered one of the commonly observed dental anomalies in children. Several theories have been proposed to …
Article scientifique
RETRACTED: The regulation of HBP1, SIRT1, and SREBP-1c genes and the related microRNAs in non-alcoholic fatty liver rats: The association with the folic acid anti-steatosis
Folic acid is one of the vital micronutrients that contribute to the genetic stability and other biological activities. In addition, …