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Publications
7361 publication(s) trouvée(s)
Article scientifique
A continent-wide high genetic load in African buffalo revealed by clines in the frequency of deleterious alleles, genetic hitchhiking and linkage disequilibrium
A high genetic load can negatively affect population viability and increase susceptibility to diseases and other environmental stressors. Prior microsatellite …
Article scientifique
The computational analyses, molecular dynamics of fatty-acid transport mechanism to the CD36 receptor
The transmembrane glycoprotein CD36, which is responsible of the metabolic disorders, and the elevated intake of fat induces lipid buildup, …
Article scientifique
Transcriptome Analysis of Eucalyptus grandis Implicates Brassinosteroid Signaling in Defense Against Myrtle Rust (Austropuccinia psidii)
Eucalyptus grandis, in its native Australian range, varies in resistance to Austropuccinia psidii (syn. Puccinia psidii). The biotrophic rust fungus, …
Article scientifique
Prognostic Significance of Long Non Coding RNA ANRIL and SNHG14 in Acute Myeloid Leukemia
BACKGROUND: Long non-coding RNAs (lnRNAs) play a pivotal role in various malignancies including AML. Therefore, we decided to study both …
Article scientifique
Ten simple rules for developing bioinformatics capacity at an academic institution
Bioinformatics is an applied interdisciplinary field whose primary purpose is to develop and deploy computational techniques to store, organize, and …
Article scientifique
Molecular characterization of enterotoxigenic Escherichia coli toxins and colonization factors in children under five years with acute diarrhea attending Kisii Teaching and Referral Hospital, Kenya
BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is one of the leading causes of infectious diarrhea in children. There are no licensed …
Article scientifique
Overexpression of chalcone isomerase A gene in Astragalus trigonus for stimulating apigenin
Abstract Apigenin is one of the most studied flavonoids and is widely distributed in the plant kingdom. Apigenin exerts important …
Article scientifique
The spread of cholera in western Democratic Republic of the Congo is not unidirectional from East–West: a spatiotemporal analysis, 1973–2018
BACKGROUND: Cholera outbreaks in western Democratic Republic of the Congo (DRC) are thought to be primarily the result of westward …
Article scientifique
Sputum microbiota profiles of treatment-naïve TB patients in Uganda before and during first-line therapy
Information on microbiota dynamics in pulmonary tuberculosis (TB) in Africa is scarce. Here, we sequenced sputa from 120 treatment-naïve TB …
Article scientifique
Whole-Genome Sequencing-Based Antimicrobial Resistance Characterization and Phylogenomic Investigation of 19 Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-Positive Escherichia coli Strains Collected From Hospital Patients in Benin in 2019
The increasing worldwide prevalence of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli constitutes a serious threat to global public health. Surgical …
Article scientifique
Therapeutic effect of biosynthetic gold nanoparticles on multidrug-resistant Escherichia coli and Salmonella species isolated from ruminants
Background and Aim: Multidrug-resistant (MDR) pathogenic microorganisms have become a global problem in ruminants as a result of the intensive …
Article scientifique
Unraveling Admixture, Inbreeding, and Recent Selection Signatures in West African Indigenous Cattle Populations in Benin
The Dwarf Lagune and the Savannah Somba cattle in Benin are typical representatives of the endangered West African indigenous Shorthorn …
Article scientifique
Deciphering DNA Methylation in HIV Infection
With approximately 38 million people living with HIV/AIDS globally, and a further 1.5 million new global infections per year, it …
Article scientifique
Antituberculosis Therapy and Gut Microbiota: Review of Potential Host Microbiota Directed-Therapies
Tuberculosis (TB) remains a major public health concern with millions of deaths every year. The overlap with HIV infections, long …
Article scientifique
Phenotypic characterization of carbapenem non-susceptible gram-negative bacilli isolated from clinical specimens
BACKGROUND: Multidrug resistant, extremely drug-resistant, pan-drug resistant, carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings …
Article scientifique
Cholera outbreak caused by drinking unprotected well water contaminated with faeces from an open storm water drainage: Kampala City, Uganda, January 2019
Abstract Background Kampala city slums, with one million dwellers living in poor sanitary conditions, frequently experience cholera outbreaks. On 6 …
Article scientifique
Male-biased migration from East Africa introduced pastoralism into southern Africa
BACKGROUND: Hunter-gatherer lifestyles dominated the southern African landscape up to ~ 2000 years ago, when herding and farming groups started …
Article scientifique
Whole-Genome Sequencing of Gram-Negative Bacteria Isolated From Bovine Mastitis and Raw Milk: The First Emergence of Colistin mcr-10 and Fosfomycin fosA5 Resistance Genes in Klebsiella pneumoniae in Middle East
Antimicrobial resistance is a major concern in the dairy industry. This study investigated the prevalence, antimicrobial resistance phenotypes, and genome …
Article scientifique
Human microbiota research in Africa: a systematic review reveals gaps and priorities for future research
BACKGROUND: The role of the human microbiome in health and disease is an emerging and important area of research; however, …
Article scientifique
Gut microbiome composition, not alpha diversity, is associated with survival in a natural vertebrate population
BACKGROUND: The vertebrate gut microbiome (GM) can vary substantially across individuals within the same natural population. Although there is evidence …