7361
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38556
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Biologie synthétique
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Publications
7361 publication(s) trouvée(s)
Article scientifique
Computational Study of 16S rRNA of Microbe Cluster Implicated in Diarrhoeal: Phylogeny, Docking, and Dynamics
Article scientifique
Genomic and antigenic diversity of carried Klebsiella pneumoniae isolates mirrors that of invasive isolates in Blantyre, Malawi
Abstract Klebsiella pneumoniae is an antimicrobial resistance (AMR) associated pathogen of global importance, and polyvalent vaccines targeting K. pneumoniae O-antigens …
Article scientifique
Genomic analysis of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli colonising adults in Blantyre, Malawi reveals previously undescribed diversity
Abstract Escherichia coli is a ubiquitous bacterium and one of the most prevalent Gram-negative species associated with drug resistant infections. …
Article scientifique
Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues
BACKGROUND: Two series of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues were designed and synthesised as novel antimicrobial drugs through inhibition …
Article scientifique
TAGOPSIN: collating taxa-specific gene and protein functional and structural information
BACKGROUND: The wealth of biological information available nowadays in public databases has triggered an unprecedented rise in multi-database search and …
Article scientifique
Rooting Responses of Female and Male Cuttings of Leucadendron elimense E. Phillips subsp. elimense on the Type and Concentration of Auxin
Abstract Female and male plants of difficult-to-root species Leucadendron elimense subsp. elimense were investigated for rooting potential with three rooting …
Article scientifique
Effects of Nitrogenous Fertilization and some Insecticides on the Natural Enemies of Transgenic Bt Cotton Pests
Field assessment of integrated management of BT cotton pests was carried out in two consecutive seasons; 2016/2017 and 2017/2018 in …
Article scientifique
PlantPathMarks (PPMdb): an interactive hub for pathways-based markers in plant genomes
ABSTRACT: Over the past decade, the problem of finding an efficient gene-targeting marker set or signature for plant trait characterization …
Article scientifique
Systematic Review of Genomic Associations with Blood Pressure and Hypertension in Populations with African-Ancestry
Background: Despite hypertension being highly prevalent in individuals with African-ancestry, they are under-represented in large genome-wide association studies. Inclusion of …
Article scientifique
Apolipoprotein E Genetic Variation and Its Association With Cognitive Function in Rural-Dwelling Older South Africans
Apolipoprotein E (APOE) 𝜀4 allele carrier status is well known for its association with an increased likelihood of developing Alzheimer’s …
Article scientifique
Bioinformatics in Sudan: Status and challenges case study: The National University-Sudan
The ever increasing applications of bioinformatics in providing effective interpretation of large and complex biological data require expertise in the …
Article scientifique
GAS5 rs2067079 and miR-137 rs1625579 functional SNPs and risk of chronic hepatitis B virus infection among Egyptian patients
Hepatitis B virus (HBV) infection is a significant health issue worldwide.. We attempted to fulfill the molecular mechanisms of epigenetic …
Article scientifique
The Environmental Impact of Changes in Cow Productivity and Its Component Traits in South Africa's Landrace Beef Breeds
Any reduction in the carbon footprint of beef production will contribute to future sustainability. This study investigates the environmental impact …
Article scientifique
De Novo Hepatocellular Carcinoma in Hepatitis C-Related Cirrhosis: Are Advanced Glycation End Products a Key Driver?
Background and Purpose: The advanced glycation end products (AGEs) have been implicated in different diseases' pathogenesis, but their role in …
Article scientifique
Role of Maspin, CK17 and Ki-67 Immunophenotyping in Diagnosing of Pancreatic Ductal Adenocarcinoma in Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology
BACKGROUND AND STUDY AIM: One of the problems in diagnosing pancreatic ductal adenocarcinoma (PDAC) is differentiation between PDAC cells and …
Article scientifique
Carbon Monoxide in Pancreatic Islet Transplantation: A New Therapeutic Alternative to Patients With Severe Type 1 Diabetes Mellitus
Pancreatic islet transplantation is a minimally invasive procedure to replace β-cells in a subset of patients with autoimmune type 1 …
Article scientifique
Whole-exome analysis in Tunisian Imazighen and Arabs shows the impact of demography in functional variation
Human populations are genetically affected by their demographic history, which shapes the distribution of their functional genomic variation. However, the …
Article scientifique
Biosynthesis and Modulation of Terpenoid Indole Alkaloids in Catharanthus roseus: A Review of Targeting Genes and Secondary Metabolites
The medicinal plant C. roseus synthesizes biologically active alkaloids via the terpenoid indole alkaloid (TIAs) biosynthetic pathway. Most of these …
Article scientifique
Expanding the clinical phenotype associated with NIPAL4 mutation: Study of a Tunisian consanguineous family with erythrokeratodermia variabilis—Like Autosomal Recessive Congenital Ichthyosis
Erythrokeratodermia variabilis (EKV) is a rare disorder of cornification usually associated with dominant mutations in the GJB3 and GJB4 genes …
Article scientifique
Compositional variation of the human fecal microbiome in relation to azo-reducing activity: a pilot study
BACKGROUND: Through an arsenal of microbial enzymes, the gut microbiota considerably contributes to human metabolic processes, affecting nutrients, drugs, and …