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Publications
7361 publication(s) trouvée(s)
Article scientifique
Triptolide Modulates the Expression of Inflammation-Associated lncRNA-PACER and lincRNA-p21 in Mycobacterium tuberculosis–Infected Monocyte-Derived Macrophages
Triptolide is a diterpene triepoxide, which performs its biological activities via mechanisms including induction of apoptosis, targeting of pro-inflammatory cytokines, …
Article scientifique
Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)-producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial
BACKGROUND: Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization …
Article scientifique
Plasminogen Activator Inhibitor-1 in poorly controlled vs well controlled Type-2 Diabetes Mellitus patients: A case-control study in a district hospital in Ghana
BACKGROUND: Hypofibrinolysis resulting from the up-regulation of plasminogen activator inhibitor-1 (PAI-1) usually occurs in patients with type 2 diabetes mellitus …
Article scientifique
Antiangiogenic and Proapoptotic Activities of Atorvastatin and Ganoderma lucidum in Tumor Mouse Model via VEGF and Caspase-3 Pathways
BACKGROUND: The statin drug Atorvastatin (AT) used for cholesterol reduction and Ganoderma lucidum (Gl) mushroom extract exhibited satisfactory antitumor activities …
Article scientifique
Malawian mothers’ experiences of raising children living with albinism: A qualitative descriptive study
BACKGROUND: Albinism in humans is characterised by a reduced amount of pigment (melanin) present in the skin, hair follicles and …
Article scientifique
Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice
Abstract Background Arsenic poisoning affects millions of people. The inorganic forms of arsenic are more toxic. Treatment for arsenic poisoning …
Article scientifique
Cutaneous anthrax outbreak associated with handling dead animals, Rhino Camp sub-county: Arua District, Uganda, January–May 2018
BACKGROUND: On 18 January 2018 a 40 year old man presented with skin lesions at Rhino Camp Health Centre. A …
Article scientifique
Microbial Pathogenesis and Pathophysiology of Alzheimer's Disease: A Systematic Assessment of Microorganisms' Implications in the Neurodegenerative Disease
Microbial infections have been linked to the pathogenesis and pathophysiology of Alzheimer's disease (AD) and other neurodegenerative diseases. The present …
Article scientifique
High ELF4 expression in human cancers is associated with worse disease outcomes and increased resistance to anticancer drugs
The malignant phenotype of tumour cells is fuelled by changes in the expression of various transcription factors, including some of …
Article scientifique
Non-autoimmune diabetes mellitus and the risk of virus infections: a systematic review and meta-analysis of case-control and cohort studies
Abstract A significant number of studies invoked diabetes as a risk factor for virus infections, but the issue remains controversial. …
Article scientifique
Detection of AZF microdeletions and reproductive hormonal profile analysis of infertile sudanese men pursuing assisted reproductive approaches
BACKGROUND: Male factor is the major contributor in roughly half of infertility cases. Genetic factors account for 10-15% of male …
Article scientifique
Interrogating the Impact of Intestinal Parasite-Microbiome on Pathogenesis of COVID-19 in Sub-Saharan Africa
Intestinal parasitic infections affect more than 2 billion people throughout the world with disproportionately high prevalence rates in Low- and …
Article scientifique
On the biocontrol by Trichoderma afroharzianum against Fusarium culmorum responsible of fusarium head blight and crown rot of wheat in Algeria
Abstract Background Durum wheat (Triticum durum Desf.) is one of the most important cereals in the world. Unfortunately, the wheat …
Article scientifique
Multidrug resistance pattern of Acinetobacter species isolated from clinical specimens referred to the Ethiopian Public Health Institute: 2014 to 2018 trend anaylsis
BACKGROUND: Acinetobacter species have been a leading cause of nosocomial infections, causing significant morbidity and mortality over the entire world …
Article scientifique
Small extracellular vesicle-encapsulated miR-181b-5p, miR-222-3p and let-7a-5p: Next generation plasma biopsy-based diagnostic biomarkers for inflammatory breast cancer
Inflammatory breast cancer (IBC) is a rare, but aggressive entity of breast carcinoma with rapid dermal lymphatic invasion in young …
Article scientifique
‘The medicine is not for sale’: Practices of traditional healers in snakebite envenoming in Ghana
BACKGROUND: Snakebite envenoming is a medical emergency which is common in many tropical lower- and middle-income countries. Traditional healers are …
Article scientifique
Metallo-β-lactamase and AmpC genes in Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa isolates from abattoir and poultry origin in Nigeria
Abstract Background Gram-negative bacteria (GNB) including Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae represent the most relevant reservoir of resistance …
Article scientifique
Armillaria root rot fungi host single-stranded RNA viruses
Species of Armillaria are distributed globally and include some of the most important pathogens of forest and ornamental trees. Some …
Article scientifique
A Review of the Toxicity and Phytochemistry of Medicinal Plant Species Used by Herbalists in Treating People Living With HIV/AIDS in Uganda
Introduction: Despite concerns about toxicity, potentially harmful effects and herb-drug interactions, the use of herbal medicines remains widely practiced by …
Article scientifique
Genetic substructure and complex demographic history of South African Bantu speakers
South Eastern Bantu-speaking (SEB) groups constitute more than 80% of the population in South Africa. Despite clear linguistic and geographic …