7361
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38556
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Biologie synthétique
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Publications
7361 publication(s) trouvée(s)
Article scientifique
The Apoptotic Effect of Trichinella spiralis Infection Against Experimentally Induced Hepatocellular Carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer. Prognosis of HCC remains unsatisfactory. Therefore, developing new …
Article scientifique
The effect of Aspalathus linearis (Burm.f.) R.Dahlgren and its compounds on tyrosinase and melanogenesis
Pigmentation, a process controlled by melanogenesis, plays a vital role in protecting the skin against harmful ultraviolet rays. The level …
Article scientifique
The overexpression of DNA repair genes in invasive ductal and lobular breast carcinomas: Insights on individual variations and precision medicine
In the era of precision medicine, analyzing the transcriptomic profile of patients is essential to tailor the appropriate therapy. In …
Article scientifique
The burden of hyaline membrane disease, mortality and its determinant factors among preterm neonates admitted at Debre Tabor General Hospital, North Central Ethiopia: A retrospective follow up study
BACKGROUND: Hyaline membrane disease (HMD) is a leading cause of morbidity and mortality in preterm newborn babies. Though, there are …
Article scientifique
Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria
Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many …
Article scientifique
Mining of two novel aldehyde dehydrogenases (DHY-SC-VUT5 and DHY-G-VUT7) from metagenome of hydrocarbon contaminated soils
Abstract Background Aldehyde dehydrogenases are vital for aerobic hydrocarbon degradation and is involved in the last step of catalysing the …
Article scientifique
Prioritization of candidate genes for a South African family with Parkinson’s disease using in-silico tools
Parkinson's disease (PD) is a neurodegenerative disorder exhibiting Mendelian inheritance in some families. Next-generation sequencing approaches, including whole exome sequencing …
Article scientifique
A survey of dimension reduction and classification methods for RNA-Seq data on malaria vector
Abstract Recently unique spans of genetic data are produced by researchers, there is a trend in genetic exploration using machine …
Article scientifique
Modeling the spatial distribution of anthrax in southern Kenya
BACKGROUND: Anthrax is an important zoonotic disease in Kenya associated with high animal and public health burden and widespread socio-economic …
Article scientifique
Intestinal protozoan infections shape fecal bacterial microbiota in children from Guinea-Bissau
Intestinal parasitic infections, caused by helminths and protozoa, are globally distributed and major causes of worldwide morbidity. The gut microbiota …
Article scientifique
A Metabolomics and Molecular Networking Approach to Elucidate the Structures of Secondary Metabolites Produced by Serratia marcescens Strains
An integrated approach that combines reverse-phase high-performance liquid chromatography (RP-HPLC), electrospray ionization mass spectrometry, untargeted ultra-performance liquid chromatography coupled to …
Article scientifique
Novel and recurrent BRCA1/BRCA2 germline mutations in patients with breast/ovarian cancer: a series from the south of Tunisia
BACKGROUND: The incidence of breast cancer (BC) and/or ovarian cancer (OC) is increasing in Tunisia especially in young women and …
Article scientifique
Multidrug resistance and extended-spectrum beta-lactamase producing Gram-negative bacteria from three Referral Hospitals of Amhara region, Ethiopia
BACKGROUND: Multidrug resistance (MDR), extended-spectrum beta-lactamase (ESBL) and carbapenemase-producing Gram-negative bacteria (GNB) has become a public health threat worldwide. This …
Article scientifique
Detection of harmful foodborne pathogens in food samples at the points of sale by MALDT-TOF MS in Egypt
OBJECTIVES: Microbes can contaminate foodstuffs resulting in foodborne illnesses. Investigating microbial hazards in foods at the point of sale with …
Article scientifique
Ugandan stakeholder hopes and concerns about gene drive mosquitoes for malaria control: new directions for gene drive risk governance
BACKGROUND: The African Union's High-Level Panel on Emerging Technologies identified gene drive mosquitoes as a priority technology for malaria elimination. …
Article scientifique
SARS-CoV-2 Antigens Expressed in Plants Detect Antibody Responses in COVID-19 Patients
Background : The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has swept the world and poses a significant global …
Article scientifique
Telocytes are major constituents of the angiogenic apparatus
The current study investigated role of telocytes (TCs) in angiogenesis during embryonic development of quail using immunohistochemistry (IHC), transmission electron …
Article scientifique
Developmental events and cellular changes occurred during esophageal development of quail embryos
The current study focused on the histogenesis of the esophagus in quail embryos. Formation of the gut tube occurred on …
Article scientifique
Vaccinomic approach for novel multi epitopes vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
BACKGROUND: The spread of a novel coronavirus termed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in China and other countries is …
Article scientifique
Prevalence of pathogenic Klebsiella pneumoniae based on PCR capsular typing harbouring carbapenemases encoding genes in Uganda tertiary hospitals
BACKGROUND: Klebsiella pneumoniae is an opportunistic pathogen that has been implicated as one of commonest cause of hospital and community …