7361
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Biologie synthétique
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Publications
7361 publication(s) trouvée(s)
Article scientifique
Assessment of the Diagnostic Potential of miR-29a-3p and miR-92a-3p as Circulatory Biomarkers in Acute Myeloid Leukemia
BACKGROUND: Acute myeloid leukemia (AML) is a set of Myeloproliferative neoplasms that are identified by excessive growth of myeloid blasts …
Article scientifique
Identifying sequence variants contributing to hereditary breast and ovarian cancer in BRCA1 and BRCA2 negative breast and ovarian cancer patients
Families with breast and ovarian cancer are often tested for disease associated sequence variants in BRCA1 and BRCA2. Pathogenic sequence …
Article scientifique
Virus-based pharmaceutical production in plants: an opportunity to reduce health problems in Africa
BACKGROUND: Developing African countries face health problems that they struggle to solve. The major causes of this situation are high …
Article scientifique
Investigation of potential pathogenicity of Willaertia magna by investigating the transfer of bacteria pathogenicity genes into its genome
Willaertia magna c2c maky is a thermophilic amoeba closely related to the genus Naegleria. This free-living amoeba has the ability …
Article scientifique
BayesMetab: treatment of missing values in metabolomic studies using a Bayesian modeling approach
BACKGROUND: With the rise of metabolomics, the development of methods to address analytical challenges in the analysis of metabolomics data …
Article scientifique
Microbial Diversity in Bushmeat Samples Recovered from the Serengeti Ecosystem in Tanzania
Bushmeat, the meat and organs derived from wildlife species, is a common source of animal protein in the diets of …
Article scientifique
vhcub: Virus-host codon usage co-adaptation analysis
Viruses show noticeable evolution to adapt and reproduce within their hosts. Theoretically, patterns and factors that affect the codon usage …
Article scientifique
The alternative cap-binding complex is required for antiviral defense in vivo
Cellular response to environmental challenges requires immediate and precise regulation of transcriptional programs. During viral infections, this includes the expression …
Article scientifique
PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells
BACKGROUND: Spermatogonial stem cells (SSCs) are the cornerstone of sperm production and thus perpetual male fertility. In clinics, transplantation of …
Article scientifique
Characterization of Holstein and Normande whole milk miRNomes highlights breed specificities
The concept of milk as a healthy food has opened the way for studies on milk components, from nutrients to …
Article scientifique
Phylogeography, genetic diversity, and population structure of Nile crocodile populations at the fringes of the southern African distribution
Nile crocodiles are apex predators widely distributed in sub-Saharan Africa that have been viewed and managed as a single species. …
Article scientifique
Glycated albumin as a diagnostic tool in diabetes: An alternative or an additional test?
INTRODUCTION: Studies have revealed that glycated albumin (GA) is a useful alternative to HbA1c under conditions wherein the latter does …
Article scientifique
Controlling invasive Argentine ants, Linepithema humile, in conservation areas using horizontal insecticide transfer
Invasive ants are major agricultural and urban pests and a significant concern in conservation areas. Despite long history of control …
Article scientifique
New Perspectives on Plant Adenylyl Cyclases
It is increasingly clear that plant genomes encode numerous complex multi-domain proteins that harbour functional adenylyl cyclase (AC) centres. These …
Article scientifique
Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion
Prion or PrPSc is the proteinaceous infectious agent causing prion diseases in various mammalian species. Despite decades of research, the …
Article scientifique
Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins
Many traits vary among isogenic individuals in homogeneous environments. In microbes, plants and animals, variation in the protein chaperone system …
Article scientifique
Optimizing sgRNA length to improve target specificity and efficiency for the GGTA1 gene using the CRISPR/Cas9 gene editing system
The CRISPR/Cas9 gene editing system has enhanced the development of genetically engineered animals for use in xenotransplantation. Potential limitations to …
Article scientifique
Genomic insights into Vibrio cholerae O1 responsible for cholera epidemics in Tanzania between 1993 and 2017
BACKGROUND: Tanzania is one of seven countries with the highest disease burden caused by cholera in Africa. We studied the …
Article scientifique
Cultivated Olive Diversification at Local and Regional Scales: Evidence From the Genetic Characterization of French Genetic Resources
Molecular characterization of crop genetic resources is a powerful approach to elucidate the origin of varieties and facilitate local cultivar …
Article scientifique
Improvement and use of CRISPR/Cas9 to engineer a sperm-marking strain for the invasive fruit pest Drosophila suzukii
BACKGROUND: The invasive fruit pest Drosophila suzukii was reported for the first time in Europe and the USA in 2008 …