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Publications
7361 publication(s) trouvée(s)
Article scientifique
Ultrastructure of the fertilized egg envelopes in Hemigrammus erythrozonus, Characidae, Teleostei
We examined the morphology and ultrastructures of fertilized egg envelopes of glowlight tetra (Hemigrammus erythrozonus) belong to Characidae using light …
Article scientifique
Retrospective Study of the Effect of Statins on the Outcome of Lung Cancer Patients, University of Cincinnati Experience
Objectives: Numerous studies addressed the effect of statin on cancer patients. The aim of this study is to define the …
Article scientifique
Ectopic activation of WNT signaling in human embryonal carcinoma cells and its effects in short- and long-term in vitro culture
Abstract Human embryonal carcinoma (EC) cells comprise the pluripotent stem cells of malignant non-seminomatous germ cell tumors (GCTs) and represent …
Article scientifique
THK5351 and flortaucipir PET with pathological correlation in a Creutzfeldt-Jakob disease patient: a case report
THK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target bindings have been reported. …
Article scientifique
Clinical MetaData ontology: a simple classification scheme for data elements of clinical data based on semantics
BACKGROUND: The increasing use of common data elements (CDEs) in numerous research projects and clinical applications has made it imperative …
Article scientifique
NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors
BACKGROUND: Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant brain tumors with inactivation of the SMARCB1 gene, which play a critical …
Article scientifique
Fundamental differences in patterns of retinal ageing between primates and mice
Photoreceptors have high metabolic demands and age rapidly, undermining visual function. We base our understanding mainly on ageing mice where …
Article scientifique
TRAF2 Controls Death Receptor-Induced Caspase-8 Processing and Facilitates Proinflammatory Signaling
Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) knockout (KO) cells were generated to investigate the role of TRAF2 in …
Article scientifique
Genetic, clinical and biochemical characterization of a large cohort of patients with hyaline fibromatosis syndrome
BACKGROUND: Hyaline fibromatosis syndrome (HFS) is a rare clinical condition in which bi-allelic variants in ANTXR2 are associated with extracellular …
Article scientifique
Prognostic value of biomarkers EpCAM and αB-crystallin associated with lymphatic metastasis in breast cancer by iTRAQ analysis
BACKGROUND: Metastasis is responsible for the majority of deaths in a variety of cancer types, including breast cancer. Although several …
Article scientifique
Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells
Lipophagy degrades lipid droplets (LDs) through the lysosomal degradative pathway, thus plays important roles in regulating lipid metabolism in mammals. …
Article scientifique
Widespread antimicrobial resistance among bacterial infections in a Rwandan referral hospital
BACKGROUND: Resistance among bacterial infections is increasingly well-documented in high-income countries; however, relatively little is known about bacterial antimicrobial resistance …
Article scientifique
Behavioural compass: animal behaviour recognition using magnetometers
Animal-borne data loggers today often house several sensors recording simultaneously at high frequency. This offers opportunities to gain fine-scale insights …
Article scientifique
An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial
BACKGROUND: This study focuses on genetically stratified subgroups of Parkinson's disease patients (PD) with an enrichment of risk variants in …
Article scientifique
High snakebite underreporting rate in the Centre Region of Cameroon: an observational study
BACKGROUND: In Cameroon, since the first epidemiological week held in 2015, snakebites have been registered among Potential Epidemic Diseases (PED). …
Article scientifique
ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells
BACKGROUND: HER3/ErbB3 receptor deletion or blockade leads to tumor cell apoptosis, whereas its overexpression confers anti-cancer drug resistance through upregulation …
Article scientifique
RNA sequencing analysis of Cymbidium goeringii identifies floral scent biosynthesis related genes
BACKGROUND: Cymbidium goeringii belongs to the Orchidaceae, which is one of the most abundant angiosperm families. Cymbidium goeringii consist with …
Article scientifique
Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target
BACKGROUNDS: The role of sphere-forming culture in enriching subpopulations with stem-cell properties in hepatocellular carcinoma (HCC) is unclear. The present …
Article scientifique
Constraints to counting bioluminescence producing cells by a commonly used transgene promoter and its implications for experimental design
It is routine to genetically modify cells to express fluorescent or bioluminescent reporter proteins to enable tracking or quantification of …
Article scientifique
Methylation of Glutathione-S-Transferase P1 Promotor in Egyptian Females with Breast Cancer
Background: Breast cancer (BC) is the second most common cancer after the lung cancer worldwide and number one killing cancer …