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7361 publication(s) trouvée(s)
Article scientifique
KPNA3 Confers Sorafenib Resistance to Advanced Hepatocellular Carcinoma via TWIST Regulated Epithelial-Mesenchymal Transition
Sorafenib, a multikinase inhibitor, is a new standard treatment for patients with advanced hepatocellular carcinoma (HCC). However, resistance to this …
Article scientifique
Investigating the virulence genes and antibiotic susceptibility patterns of Vibrio cholerae O1 in environmental and clinical isolates in Accra, Ghana
Cholera has been endemic in Ghana since its detection in 1970. It has been shown that long-term survival of the …
Article scientifique
Fabrication of gold/graphene nanostructures modified ITO electrode as highly sensitive electrochemical detection of Aflatoxin B1
Aflatoxins (AFs) are a family of fungal toxins that produced in food and feed by two Aspergillus species (Aspergillus flavus …
Article scientifique
ISL1 predicts poor outcomes for patients with gastric cancer and drives tumor progression through binding to the ZEB1 promoter together with SETD7
ISL1, a LIM-homeodomain transcription factor, serves as a biomarker of metastasis in multiple tumors. However, the function and underlying mechanisms …
Article scientifique
Immunohistochemical Evaluation of Ki-67 and Comparison with Clinicopathologic Factors in Breast Carcinomas
Background: Patients primarily received tamoxifen based on their menopausal status due to the lack of immunohistochemistry. A recent study has …
Article scientifique
miR-1307-3p Stimulates Breast Cancer Development and Progression by Targeting SMYD4
Recent studies show that dysregulated miRNAs play an important role in breast cancer initiation and progression. Here, we identified upregulated …
Article scientifique
The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness
BACKGROUND: Disruptor of telomeric silencing 1-like (DOT1L) is a non-SET domain containing methyltransferase known to catalyze mono-, di-, and tri-methylation …
Article scientifique
Lightweight Convolutional Neural Network for Breast Cancer Classification Using RNA-Seq Gene Expression Data
Gene expressions are considered among the most used features in cancer classification. The available gene expression data has a small …
Article scientifique
Antimicrobial resistance genes in Salmonella and Escherichia coli isolates from chicken droppings in Nairobi, Kenya
Increase in antimicrobial resistance is a threat to health sector globally. Surveillance on the spread and emergence of antimicrobial resistance …
Article scientifique
Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization
BACKGROUND: The estrogen metabolite 2-methoxyestradiol (2ME2) and a number of synthesised derivatives have been shown to bind to microtubules thereby …
Article scientifique
CDCA5, Transcribed by E2F1, Promotes Oncogenesis by Enhancing Cell Proliferation and Inhibiting Apoptosis via the AKT Pathway in Hepatocellular Carcinoma
Cell division cycle associated 5 (CDCA5) is an important element for the interaction between cohesin and chromatin in interphase. It …
Article scientifique
Evaluation of antibiotic susceptibility test results: how guilty a laboratory could be?
The selection of an appropriate antimicrobial is a challenging task for clinicians. The Kirby-Bauer disk diffusion method is one of …
Article scientifique
Identification of potential miRNA–mRNA regulatory network contributing to pathogenesis of HBV-related HCC
BACKGROUND: Hepatitis B virus (HBV) is one of the major risk factors of hepatocellular carcinoma (HCC). Increasing evidence indicates that …
Article scientifique
Detection and Characterization of ESBL-Producing Escherichia coli From Humans and Poultry in Ghana
Introduction: The increasing incidence of infections caused by Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in sub-Saharan Africa is of serious concern. …
Erratum
Correction to: New cryptic species of Teratosphaeria on Eucalyptus in Australia
In Table 1 in the paper by Adjic et al. ( IMA Fungus 7 : 253–263, 2016), the location of …
Article scientifique
RISK FACTORS ASSOCIATED WITH ABORTION AND CALF PREWEANING MORTALITY IN A BEEF CATTLE SYSTEM IN SOUTHEASTERN MEXICO
Data from 2438 calvings born to 682 cows recorded from 2004 to 2015 in an extensive production system were used, …
Article scientifique
Prevalence of protective tetanus antibodies and immunological response following tetanus toxoid vaccination among men seeking medical circumcision services in Uganda
INTRODUCTION: Tetanus infection associated with men who had male circumcision has been reported in East Africa, suggesting a need for …
Article scientifique
Prognostic Value of BCL2 in Women Patients with Invasive Breast Cancer
Background: Breast cancers are heterogeneous, making it essential to recognize several biomarkers for cancer outcome predictions especially in young women …
Article scientifique
Integrated genome sizing (IGS) approach for the parallelization of whole genome analysis
BACKGROUND: The use of whole genome sequence has increased recently with rapid progression of next-generation sequencing (NGS) technologies. However, storing …
Article scientifique
Full-Length Envelope Analyzer (FLEA): A tool for longitudinal analysis of viral amplicons
Next generation sequencing of viral populations has advanced our understanding of viral population dynamics, the development of drug resistance, and …