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7361 publication(s) trouvée(s)
Article scientifique
The reporting of a Bacillus anthracis B-clade strain in South Africa after more than 20 years
OBJECTIVES: Anthrax is a disease with an age old history in Africa caused by the Gram-positive endospore forming soil bacterium …
Article scientifique
Homozygous deletion of both GSTM1 and GSTT1 genes is associated with higher CD4+ T cell counts in Ghanaian HIV patients
Glutathione S-transferase (GST) family of enzymes are involved in a two-stage detoxification process of a wide range of environmental toxins, …
Article scientifique
High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints
RNA not only translates the genetic code into proteins, but also carries out important cellular functions. Understanding such functions requires …
Article scientifique
Highly targeted cholera vaccination campaigns in urban setting are feasible: The experience in Kalemie, Democratic Republic of Congo
INTRODUCTION: Oral cholera vaccines are primarily recommended by the World Health Organization for cholera control in endemic countries. However, the …
Article scientifique
Delayed double reading of whole blood clotting test (WBCT) results at 20 and 30 minutes enhances diagnosis and treatment of viper envenomation
BACKGROUND: The whole blood clotting test (WBCT) is a simple test of coagulation that is often used in the assessment, …
Article scientifique
Differential modulation of host immune genes in the kidney and cranium of the rainbow trout (Oncorhynchus mykiss) in response to Tetracapsuloides bryosalmonae and Myxobolus cerebralis co-infections
BACKGROUND: Most of the studies on fish diseases focus on single infections, although in nature co-infections occur more often. The …
Article scientifique
PDXliver: a database of liver cancer patient derived xenograft mouse models
BACKGROUND: Liver cancer is the second leading cause of cancer-related deaths and characterized by heterogeneity and drug resistance. Patient-derived xenograft …
Article scientifique
Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish
Impaired mitochondrial fatty acid β-oxidation has been correlated with many metabolic syndromes, and the metabolic characteristics of the mammalian models …
Article scientifique
Discovery of chitin in skeletons of non-verongiid Red Sea demosponges
Marine demosponges (Porifera: Demospongiae) are recognized as first metazoans which have developed over millions of years of evolution effective survival …
Article scientifique
Genetic Diversity of Seven Cattle Breeds Inferred Using Copy Number Variations
Copy number variations (CNVs) comprise deletions, duplications and insertions found within the genome larger than 50bp in size. CNVs are …
Article scientifique
Faecal colonization of E. coli and Klebsiella spp. producing extended-spectrum beta-lactamases and plasmid-mediated AmpC in Mozambican university students
BACKGROUND: In recent years, the world has seen a surge in Enterobacteriaceae resistant to broad-spectrum beta-lactam antibiotics due to the …
Article scientifique
Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S
Endoglycosidase S (EndoS) is a bacterial endo-β-N-acetylglucosaminidase that specifically catalyzes the hydrolysis of the β-1,4 linkage between the first two …
Article scientifique
Epidemiology and diagnosis of feline panleukopenia virus in Egypt: Clinical and molecular diagnosis in cats
AIM: This work aimed to study epidemiology and diagnosis of feline panleukopenia virus (FPV) using clinical examination, direct ELISA, RNA …
Article scientifique
Curcumin-Artesunate Based Polymeric Nanoparticle; Antiplasmodial and Toxicological Evaluation in Murine Model
Mainstay chemotherapy for malaria is often faced with the problem of instability and poor bio-distribution thus resulting in impaired pharmacokinetics. …
Article scientifique
Distinct domains of Escherichia coli IgaA connect envelope stress sensing and down-regulation of the Rcs phosphorelay across subcellular compartments
In enterobacteria, the Rcs system (Regulator of capsule synthesis) monitors envelope integrity and induces a stress response when damages occur …
Article scientifique
Using genetic markers to unravel the origin of birds converging towards pre-migratory sites
Identifying patterns of individual movements in spatial and temporal scales can provide valuable insight into the structure of populations and …
Article scientifique
A novel oral camptothecin analog, gimatecan, exhibits superior antitumor efficacy than irinotecan toward esophageal squamous cell carcinoma in vitro and in vivo
Abstract Esophageal squamous cell carcinoma (ESCC) is a frequently diagnosed and deadly malignancy with few standard therapeutic options. Camptothecins are …
Article scientifique
Antimicrobial and antioxidant activities of triterpenoid and phenolic derivatives from two Cameroonian Melastomataceae plants: Dissotis senegambiensis and Amphiblemma monticola
BACKGROUND: Antimicrobial resistance is a serious threat against humankind and the search for new therapeutics is needed. This study aims …
Article scientifique
Evaluation of anaesthetic protocols for laboratory adult zebrafish (Danio rerio)
In the last decades, the use of zebrafish (Danio rerio) in biomedical research has increased. Anaesthesia is daily used in …
Article scientifique
The Presence or Absence of Intestinal Microbiota Affects Lipid Deposition and Related Genes Expression in Zebrafish (Danio rerio)
Understanding how intestinal microbiota alters energy homeostasis and lipid metabolism is a critical process in energy balance and health. However, …